Ruchi Patel
@_ruchipatel
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Graduated but still working on my thesis project… • NCSU ‘17 • JHU ‘19 • UPenn ‘24
Philadelphia, PA
Joined February 2020
RT @PatriziaPorazzi: Exciting news: EZH1/EZH2 inhibition enhances adoptive T cell immunotherapy against multiple cancer models @Cancer_Cell….
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RT @ngaboreden: Excited to share our latest work on bioRxiv! Using cell-cycle dynamics and NIPBL depletion, we show that long-range enhance….
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RT @ngaboreden: Our paper is now online @MolecularCell. Architectural protein LDB1 drives enhancer connectivity in….
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RT @PuneethGuru_: Wild experience to have seen our story shared at the #ASH24 Plenary in San Diego by my wonderful co-lead @Shan_Liu_ ! Loo….
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RT @AlbertoCarturan: Grateful to #ASH2024 for the chance to present our work on overcoming the absence of CD2:CD58 co-stimulation using an….
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RT @PennMedicine: Learn more about the exciting advances in blood cancer and benign hematology research that Penn Medicine and @PennCancer….
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RT @PennMedicine: A simple dietary supplement may provide a new approach to boost #CART cell function – hear more in the #ASH24 Plenary Ses….
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Looking forward to discussing our latest work on CD5 next week! Register here to join:
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RT @KartikPatel___: Very excited to share this work that could not have been done without the help of @RaisBahrami and @arnabguonc ! Big th….
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RT @ngaboreden: Happy to share my thesis work, now online at bioRxiv. We show that LDB1 organizes Enhancer-Promoter interaction networks an….
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RT @PennCancer: The effectiveness of #CARTCellTherapy against a variety of cancers, including solid tumors, could be boosted greatly by usi….
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RT @PennMedCSO: In a study published in @SciImmunology, @PennMedicine researchers identify #CD5 as an immune checkpoint protein & potential….
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RT @parkerici: @UCLA @UCSF @cityofhope @DanaFarber A discovery from PICI Investigators @Penn has revealed that deleting the CD5 gene in CAR….
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RT @ACIR_org: Patel et al. used the CRISPR-Cas9 system to ablate expression of the TCR-associated T cell inhibitory receptor CD5 from CAR T….
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Looking forward to joining @pillar_vc Frequency Bio's Cohort 10 next week! Excited to learn more about the biotech startup community.
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RT @SciImmunology: Genetic deletion of #CD5 in CAR T cells given to mice led to enhanced expansion, persistence, and anti-tumor effects aga….
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RT @BLLPHD: NEW -CD5 deletion enhances the antitumor activity of adoptive T cell therapies in vivo (liquid & solid cancer models) by enhanc….
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RT @PennMedicine: A @PennCancer research team led by @MarcoRuella has found that CD5 knockout boosts #CARTcell anti-tumor efficacy, in a pr….
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Our paper is out in Science Immunology! As you can see from the author list, this was truly a team effort and I am so grateful for everyone’s support, especially @MarcoRuella for his mentorship. Next stop: continuing my thesis work into clinical translation at Vittoria Bio 🙂.
According to a new Science #Immunology study in mice, the #CD5 receptor limits CAR T cell activation and may contribute to poor outcomes from adoptive #Tcell #immunotherapies. 📄:
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