André Dias
@_andre_Dias_
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Developmental biologist at @AMA_lab @UPFbiomed. Moving to @dias-andre.bsky.social
Joined May 2017
Here we explore the role of #Wnt and #Nodal signalling during mammalian gastrulation using #gastruloids. Building on the work of many labs, we propose that antagonistic signalling-dependent #modularity in the PS establishes the early mammalian body plan.
biorxiv.org
Nodal and Wnt signalling play an important role in the emergence of the mammalian body plan, primarily by orchestrating gastrulation and primitive streak formation. While the literature suggests that...
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Catch up on Development presents… July webinar on early embryogenesis Featuring talks from @Lakshmib02, @_andre_Dias_ and Nikhil Mishra 🎥 https://t.co/FPPno0zqTF
@Dev_journal
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Tune in tomorrow if you are interested in understanding how stem cells can be coaxed to make different parts of our body
Sign up to attend our next Development presents... webinar on early #embryogenesis, featuring talks from @Lakshmib02, @_andre_Dias_ and Nikhil Mishra. 📅Wed 9 July 15:00BST (UTC+1) Register here: https://t.co/uKJOAB9LO3
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In which we discuss the homologies between amphibian and mammalian #organizers from the perspective of #gastruloids with special relevance to recently described A and C gastruloids as containing Spemann/Mangold and Trunk/Tail organizers https://t.co/AX9dWdUDEZ
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We've just updated our manuscript to a more 'publishable' version! https://t.co/wT8ma3mWqQ New details about the role of Wnt in suppressing neural differentiation and fostering a posterior epiblast state, and the temporal effect of Nodal signalling in driving mesendodermal fates
Here we explore the role of #Wnt and #Nodal signalling during mammalian gastrulation using #gastruloids. Building on the work of many labs, we propose that antagonistic signalling-dependent #modularity in the PS establishes the early mammalian body plan.
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Opposing Nodal and Wnt signalling activities govern the emergence of the mammalian body plan
biorxiv.org
Nodal and Wnt signalling play an important role in the emergence of the mammalian body plan, primarily by orchestrating gastrulation. While the literature suggests they cooperate to build the...
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Great work from Alexandra and Sebastian et al showing how gastrulation is governed downstream of Wnt and Nodal. Two competing transcriptional modules, two opposing signalling activities, orchestrate the emergence of the mammalian body plan. moving forward, together
Two transcriptional modules that control mammalian #gastrulation that are functionally linked through their GRNs https://t.co/FFTw6o4nWJ and paced by interactions between Wnt and Nodal signalling @realArnoldLab #gastruloids
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Just published a new edition of “Principles of Development’ from “Wolpert’s Principles of Development’ to honour his memory and the origin of this textbooks that aims at distilling the, sometimes elusive, principles underlying animal and plant development https://t.co/eNCTuQAHtj
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Being able to bring together part of the #gastruloid community in this special meeting was incredible. Thank you all for participating in this event, and keep up the great science!
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Fun collaboration! All the nitty-gritty about N2B27 and gastruloids. Kudos to all the authors, particularly Tina Balayo (¡que va de primero!)
New Gastruloid preprint just landed... nice collaboration between our lab, @_andre_Dias_ and @AMartinezArias
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Please repost - some places available for students who desire to learn all about stem cells, and then some, in a great environment with leading experts in the respective fields.
Time flies! ⏳ Throwback to the 6th edition (2017-2018) of our #Stem #Cells & #Organoids Course at @institutpasteur. 🚀 Apply now — spots are limited & reviewed on a rolling basis! Next edition: June 23–July 4, 2025 🔗 https://t.co/KEtt1fpn7p
#ScientificTraining #ASCBcourse
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For some time now we’ve been aware that Chiron #gastruloids, while representing well axial elongation, exhibit a shortage of anterior fates. Here https://t.co/VyvomYxTJT led by @_andre_Dias_ we uncover the reason
biorxiv.org
Nodal and Wnt signalling play an important role in the emergence of the mammalian body plan, primarily by orchestrating gastrulation and primitive streak formation. While the literature suggests that...
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Acknowledgements to Pau, Gabriel, @h4rrymcnamara , Alexandra, @realArnoldLab, @AMartinezArias and the @AMA_lab ! This work was carried out @UPFbiomed and mostly funded by @EMBO and @ERC_Research. Watch out for Alexandra’s complementary work. (more soon to come!)
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Nodal builds the anterior part in a concentration/time-dependent manner, regulating mesendodermal differentiation. Wnt paces gastrulation by controlling the state transition leading to the caudal epiblast emergence (#NMPs). CHIR and Activin gastruloids mimic these two modules.
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📣 DO NOT MISS NEXT NIMSBinar!!!📣 🗓️ Date: November 26th ⏰ Time: 1 pm CET 💻 Where: Online 🎟️ Register here: https://t.co/ZGrCTxVDLk Registration is free but mandatory! To learn more about our virtual seminars visit our website: https://t.co/NnvQU4qi4O
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Reminder that pre-registration for the 2025 Gastruloid Meeting ends November 30th! About 55 participants have already booked their seat at the meeting, we still have about 45 spots available. Pre-register now 👇
🚨You've been waiting for it, here it is! The Gastruloid Meeting will take place in Barcelona, Spain on March 20-21st 2025. Registration will be free but mandatory. Please let us know already if you plan on attending, using this link: https://t.co/4TXMbTwaYO Spread the word!
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Registration is open for a Symposium on “Cells and Embryos: #NotInTheGenes” in La Pedrera, Barcelona. 18/19 of September 2025. Attendance is free but you need to register https://t.co/3fO7kUlLcu Stembryo lab @UPFbiomed @ERC_Research
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🚨You've been waiting for it, here it is! The Gastruloid Meeting will take place in Barcelona, Spain on March 20-21st 2025. Registration will be free but mandatory. Please let us know already if you plan on attending, using this link: https://t.co/4TXMbTwaYO Spread the word!
docs.google.com
Dear all, The lab of Alfonso Martinez Arias is organizing a gastruloid meeting at the Barcelona Biomedical Research Park (PRBB), in Barcelona (Spain), on March 20th-21st, 2025 (Thursday afternoon and...
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Ready for the next VGZT episode?? 🌟 Mark your calendar and join us for two fascinating talks on signalling and morphogenesis with @_andre_Dias_ 🐭 and @Mattia__Serra 🐥 🗓️ Oct 24, 12:30 EST / 18:30 CET / 16:30 UTC 🕥
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We're hiring! Are you an outstanding scholar in developmental biology looking for a tenure-track faculty position? Our cutting-edge research program is searching for brilliant minds to make groundbreaking discoveries. Apply Now https://t.co/iaLYCj2R4M
#FacultyPosition
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