Christian Zierhut
@ZierLab
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Scientist at the Institute of Cancer Research, London | Genome Stability and Innate Immunity Lab | CRUK Career Development Fellow https://t.co/dStQ0Hdnub
Joined June 2014
The lab’s first pre-print is out! ‘A microscopy reporter for cGAMP reveals rare cGAS activation following DNA damage, and a lack of correlation with micronuclear cGAS enrichment’
biorxiv.org
Cyclic GMP-AMP (cGAMP) synthase (cGAS) is the primary intracellular responder to pathogen DNA. Upon DNA-binding, cGAS generates cGAMP, which binds to STING, ultimately driving inflammatory signalli...
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If you have just finished your PhD (2023 or 2024) and are looking for a postdoc position in Spain, we are inviting researchers to apply for the "Juan de la Cierva Fellowship program". We have cool ongoing projects in the lab. Please get in touch! https://t.co/UKTcVkOxm3
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If you're looking for a postdoc position, consider this one! Highly recommended!
JOB ALERT!🚨 The @MansfeldLab is #hiring a Postdoc to characterise how protein oxidation regulates cell cycle proteins involved in #DNAReplication, #DNADamage, or #Ubiquitylation. Don’t miss out, apply!
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Professor Kevin Harrington and Dr @alison_tree share how @CR_UK's 'RadNet' funding will enable the ICR and @royalmarsdenNHS to make #Radiotherapy treatments more targeted and gentler, benefitting patients for years to come. https://t.co/m5PaPjGIk8
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Interested in innate immunity and genome instability? Consider joining our lab! Only a couple of days left to apply for a fully-funded postdoc position. More information here:
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Couldn't have asked for a better end to the amazing #NAIS2024 meeting, with @vvnlebrec being awarded one of the poster awards! Thank you to all the organisers, and also to all the lab's contributors to Vivianne's project!
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We have a project available to join the CRUK City of London MBPhD Programme at QMUL starting in 2025. Check out project details here https://t.co/WxGPjENCuw and CRUK CoL training opportunities and eligibility requirements here https://t.co/zhpGy9msh6
https://t.co/mTZ3GmvFG2
colcc.ac.uk
CRUK CoL Centre MBPhD studentships The CRUK CoL Centre is able to fund 3-year MBPhD studentships as part of the UCL and Queen Mary University of London (QMUL) MBPhD programmes starting in September...
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If you like this kind of work we have a funded PhD place in the lab starting in Oct 2025 to explore antiviral innate immune responses across species. See here for details of how to apply or ask me for more info:
New preprint from the lab describing how most poxviruses, including avipoxviruses, antagonise DNA-PK to block cGAS/STING-dependent interferon production during infection. Is this a stalemate in the molecular host/pathogen arms race? https://t.co/jEMIz9mxdI
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I am looking for a highly motivated PhD student to join my lab @ICR_London , please help to spread the message:
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Virtual Cell Cycle Club meeting, Tuesday, October 15. PROGRAMME 3 short talks: @dnatarheel, @MansfeldLab & the @Alexis_Barr labs 6 breakout sessions talks (t.b.c)!! 1 Keynote: @BettencourtDias Don't miss out! Register (for free!) using the link below: https://t.co/WlI4UZoygs
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Hugely well-deserved award for a hugely important discovery!
Congratulations to Zhijian “James” Chen, 2024 #LaskerAward winner! – “for the discovery of the cGAS enzyme that senses foreign and self DNA, solving the mystery of how DNA stimulates immune and inflammatory responses.” https://t.co/hGFSdFMq7E
#Lasker2024 #LaskerLaureate
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New from @HironoriFunabi1's lab: CDCA7, whose mutations alter DNA methylation pattern and cause immunodeficiency, is a novel sensor for a special class of methylated DNA. #RockefellerScience
rockefeller.edu
CDCA7, whose mutations alter DNA methylation pattern and cause immunodeficiency, is a novel sensor for a special class of methylated DNA.
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Come and join our team @ICR_London! We have a well-funded Higher Scientific Officer position available, ideal for a Biochemist / Structural Biologist. The role is research-focussed with some lab management mixed in. https://t.co/lQIzDWdU0m
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Do you want to do a PhD in cancer research in the world’s most beautiful city https://t.co/JMnjYJKsFQ? Thanks to the generosity of donors and @FlindersFound, I have a fully-funded PhD position in my lab starting 2025. For more info, check out https://t.co/RcPcgNWvou and/or DM me
flinders.edu.au
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OPEN CALLS 📢📢 Are you a structural biologist looking for a drug discovery project? Join us on a collaborative project with focus on structure-based drug design! For any Q feel free to contact Marina Mapelli Deadline: August 20, 2024 https://t.co/5xyW2dOoof
research.ieo.it
The Department of Experimental Oncology (DEO) offers many different job opportunities, starting from scientists at any level (undergraduates students, PhD students, postdoc, senior scientists and...
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Super-creative and supportive PI, great lab members, fun environment, excellent projects! Could not recommend this more!
Have you ever wondered what H2O2 does in your cells? We are looking a highly motivated #Postdoc to investigate #Redox regulation of #DNAReplication and #DNADamage repair. Our lab is based at the ICR in Chelsea, London, UK. Please apply here: https://t.co/P0k77EgMWD
#mansfeldlab
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Have you ever wondered what H2O2 does in your cells? We are looking a highly motivated #Postdoc to investigate #Redox regulation of #DNAReplication and #DNADamage repair. Our lab is based at the ICR in Chelsea, London, UK. Please apply here: https://t.co/P0k77EgMWD
#mansfeldlab
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1/2 We have just advertised a post-doc position, looking for someone to investigate how DNA replication and repair -dependent processes influence haematopoietic stem cell longevity & plasticity, & counteract DNA damage-dependent clonal haematopoiesis: https://t.co/md9sGq3cx0
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A postdoc or higher scientific officer position is available in my lab from 1st September. If interested, please message me directly. Official advert to follow shortly.
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We are hiring! 📢📢 We have two open analyst positions in the IEO Mass Spectrometry Unit in Milan @IEOufficiale. Come and join us! Links to apply below
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Fun and thought-provoking times with @SteSantaguida!
Truly enjoyed visiting @EdinburghUni and the @ICR_London and presenting our work. It was great seeing old friends and discussing science!! Thanks @dynamicMT and @ZierLab for having me, I had a blast!!
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