Luke Selth
@LukeSelth
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PS – speaking of bipolar androgen therapy, you should also check out this recent review!
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This research couldn’t happen without funding and support from @MovemberAUS @nhmrc @CancerCouncilSA @hosp_research @CancerAustralia @FlindersFound @cancerFCIC @FlindersHMRI @CCNewSouthWales and others.
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This was a really enjoyable collaboration with (X-less) Mitch Lawrence and his team, plus many other wonderful colleagues.
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Check out our new work exploring AR biology in advanced prostate cancer: We found that tumours expressing a specific AR variant (ARv567es) have a distinct transcriptomic profile and are resistant to androgen deprivation and bipolar androgen therapy.
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RT @LukeIsbel: Exciting Masters/PhD opportunities in Adelaide Australia, balancing creativity, excellence and inclusion!! Please join if yo….
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RT @EpiCSA01: Don't miss the EpiCSA 9th Annual Research Meeting! Dive into groundbreaking research and network with top experts in the fiel….
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RT @miczemic: A great opportunity for talented graduates looking for a challenge. Oesophageal cancer is a disease with poor prognosis, here….
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RT @aachinger: Please RT! 🧬🧬.I am looking for a #postdoc fellow to lead a new project in 3D chromatin organisation and transcriptional regu….
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Do you want to do a PhD in cancer research in the world’s most beautiful city .Thanks to the generosity of donors and @FlindersFound, I have a fully-funded PhD position in my lab starting 2025. For more info, check out and/or DM me.
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Super short version: FOXA2 promotes transcriptional reprogramming – in collaboration with LSD1 and AP-1 – to enable prostate cancer lineage plasticity. But there is SO MUCH MORE….give it a read if chromatin/transcription/plasticity/etc float your boat.
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It was a huge pleasure to be involved in this exciting new study from @ChangmengC and @ZifengWang_ZZD just published in @NatureComms @UMassBoston @FlindersHMRI.
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And of course, this research couldn’t happen without funding and support from @MovemberAUS @nhmrc @CancerCouncilSA @hosp_research @CancerAustralia @FlindersFound @cancerFCIC @FlindersHMRI @Flinders.
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We are grateful for the wonderful collaborations that made this work possible @LisaButler5 @zeiadnassar @SwinnenJohan @HoyLipidLab @MattWattUnimelb and many other colleagues/friends.
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These AR-regulated enzymes don’t muck around: in addition to promoting tumour growth and metabolism of medium chain fatty acids, they also suppress ferroptosis and drive resistance to AR-targeted therapies. New therapeutic targets?.
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Excited to share our latest work! Adeptly led by @RajShrestha1302, we forayed into the world of prostate cancer lipid metabolism and identified ACSM1 and ACSM3 as key players in this common cancer
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Also, congrats to the other recipients (SA knocking it out of the park btw!).
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We are very grateful for support from @CancerAustralia to pursue this important research @cancerFCIC @FlindersHMRI. Big thanks to our consumer advocates and co-investigators @ReneaTaylor1 @AminaZoubeidi @parkerlabPMCC @ChrisSweens1 @dralexswarbrick @AnthonyMJoshua.
The Minister for Health and Aged Care @Mark_Butler_MP has today announced over $5.7m in funding through Cancer Australia’s Priority-driven Collaborative Cancer Research Scheme! Learn more about the successful 2023 #PdCCRS Ideas grant recipients:
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Ok I'm a little biased but I reckon this is going to be a brilliant meeting. @DrKristinBrown is one of many outstanding speakers on the program. Join us in Adelaide in May!.
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RT @acmm202446519: Prof Marcia Haigis @HaigisLab from Harvard Medical School is presenting at ACMM 2024! Prof Haigis examines mitochondrial….
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