Scientists with Drs. @LukeSelth and Jianling Xie identify the protein disulfide isomerases PDIA1 and PDIA5, which play a critical role in folding of client proteins in the ER, as important regulators of #ProstateCancer growth and response to therapy. 💊 https://t.co/DXaBouBHHz

PS – speaking of bipolar androgen therapy, you should also check out this recent review!

This research couldn’t happen without funding and support from @MovemberAUS @nhmrc @CancerCouncilSA @hosp_research @CancerAustralia @FlindersFound @cancerFCIC @FlindersHMRI @CCNewSouthWales and others

This was a really enjoyable collaboration with (X-less) Mitch Lawrence and his team, plus many other wonderful colleagues

Check out our new work exploring AR biology in advanced prostate cancer: https://t.co/SqZKXZ8kcR. We found that tumours expressing a specific AR variant (ARv567es) have a distinct transcriptomic profile and are resistant to androgen deprivation and bipolar androgen therapy

Exciting Masters/PhD opportunities in Adelaide Australia, balancing creativity, excellence and inclusion!! Please join if your interested in Genomics and making a difference through research!! Please share with your networks!!!

Don't miss the EpiCSA 9th Annual Research Meeting! Dive into groundbreaking research and network with top experts in the field. Register via the links in our poster!

A great opportunity for talented graduates looking for a challenge. Oesophageal cancer is a disease with poor prognosis, here is your chance to make a difference. https://t.co/24MbyoU8Yl

Please RT! 🧬🧬 I am looking for a #postdoc fellow to lead a new project in 3D chromatin organisation and transcriptional regulation in cancer (experimental and/or computational) at @SAiGENCI in Adelaide. Apply below: https://t.co/Uxeq1G9iI6

@FlindersHMRI @Flinders @cancerFCIC

Do you want to do a PhD in cancer research in the world’s most beautiful city https://t.co/JMnjYJKsFQ? Thanks to the generosity of donors and @FlindersFound, I have a fully-funded PhD position in my lab starting 2025. For more info, check out https://t.co/RcPcgNWvou and/or DM me

Super short version: FOXA2 promotes transcriptional reprogramming – in collaboration with LSD1 and AP-1 – to enable prostate cancer lineage plasticity. But there is SO MUCH MORE….give it a read if chromatin/transcription/plasticity/etc float your boat

It was a huge pleasure to be involved in this exciting new study from @ChangmengC and @ZifengWang_ZZD just published in @NatureComms https://t.co/gPO8Qu4KPX @UMassBoston @FlindersHMRI

And of course, this research couldn’t happen without funding and support from @MovemberAUS @nhmrc @CancerCouncilSA @hosp_research @CancerAustralia @FlindersFound @cancerFCIC @FlindersHMRI @Flinders

We are grateful for the wonderful collaborations that made this work possible @LisaButler5 @zeiadnassar @SwinnenJohan @HoyLipidLab @MattWattUnimelb and many other colleagues/friends

These AR-regulated enzymes don’t muck around: in addition to promoting tumour growth and metabolism of medium chain fatty acids, they also suppress ferroptosis and drive resistance to AR-targeted therapies. New therapeutic targets?

Excited to share our latest work! Adeptly led by @RajShrestha1302, we forayed into the world of prostate cancer lipid metabolism and identified ACSM1 and ACSM3 as key players in this common cancer https://t.co/nV7QjQBLJt

Also, congrats to the other recipients (SA knocking it out of the park btw!)

We are very grateful for support from @CancerAustralia to pursue this important research @cancerFCIC @FlindersHMRI. Big thanks to our consumer advocates and co-investigators @ReneaTaylor1 @AminaZoubeidi @parkerlabPMCC @ChrisSweens1 @dralexswarbrick @AnthonyMJoshua.

Ok I'm a little biased but I reckon this is going to be a brilliant meeting. @DrKristinBrown is one of many outstanding speakers on the program. Join us in Adelaide in May!