Yeeles Lab
@Yeeles_Lab
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We’re a lab based at @MRC_LMB in Cambridge using biochemistry and structural biology to understand how DNA replication works 🧬
MRC LMB
Joined July 2022
RT @TDDeego: Great first day of EMBL DNA replication meeting in beautiful Heidelberg, including a hike to the Schloss with @Yeeles_Lab http….
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Amazing talk from @JohannJRoske at the #LMB lab talks! Thanks to @this_clockwork for bringing the replisome to life 🧬🧬🧬
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RT @MurugarrenNerea: #DNAReplication Community 🧬🚨. I will be attending the 2nd UK DNA replication Meeting (10-12 Sept 2024, Cambridge), org….
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RT @HarryOrrin: Excited for the first day of the UK DNA Replication Meeting 2024! First up: all things initiation. @BiochemSoc #BiochemEve….
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🚨📣 Excited to share our latest work investigating how the replisome responds to topoisomerase-DNA crosslinks 🧬🔬. Fantastic work from @rosewesthorpe and @JohannJRoske 🍄🍄🍄🍄.
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We are excited to share new mechanistic insights into DNA replication fidelity! How does human DNA Polymerase Epsilon recognise and proofread errors made during synthesis? 🧬.Read @NatureSMB
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RT @this_clockwork: Here's a render of a full eukaryotic replisome carrying out DNA replication. This was built using real .pdb data from @….
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RT @TDDeego: New paper from my group, in which we use the combined power of AlphaFold and biochemical reconstitution to determine how the….
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Brilliant to see our talented postdoc, Cristian, publish his work on CMG disassembly in @embojournal. The culmination of his PhD work in the Labib lab at @dundeeuni. @TDDeego . .
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RT @TDDeego: Join us next year for the 2nd edition of the UK DNA replication meeting in Cambridge. The first meeting was fantastic so be su….
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So excited to have arrived at @cshlmeetings Eukaryotic DNA Replication and Genome Maintenance!! Can’t wait to hear all of the amazing science and catch up with old and new friends 🧬 #cshl
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RT @DiffleyLab: Hi all. Two fully funded four year postdoc positions to study DNA replication initiation using human proteins. Please check….
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RT @MolecularCell: Online Now: How Pol α-primase is targeted to replisomes to prime eukaryotic DNA replication
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Very happy and excited to share our latest work on Pol α-primase recruitment to the eukaryotic replisome! 🧬 ⬇️ #dnareplication #cryoEM #biochemistry.
🔬📚 Very excited to share our new paper titled "How Pol α-primase is targeted to replisomes to prime eukaryotic DNA replication"! 🧬 A #tweetorial below ⬇️ @MolecularCell @Yeeles_lab.#ScienceTwitter #cryoEM #replication #DNA #polymerase #primase #MolecularBiology #replisome.
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RT @rosewesthorpe: Yes, I did take my science Barbie on our @Yeeles_Lab trip to see the Barbie movie yesterday 🍿🩷 #Barbie .
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RT @patrycja_kozik: Our work on perforin-2, a pore-forming protein expressed by #DendriticCells to deliver antigens into the cytosol during….
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