An exciting PhD project opportunity in my lab @EdinUni_IGC @mrc_hgu. Informal enquiries welcome.

Congratulations to Tom Deegan who is part of the new cohort of 28 @EMBO Young Investigators! Read more 👉 https://t.co/8BmhoyuRB7 @TDDeego

Applications close this Friday!

Exciting opportunity to join us as a PhD student and kickstart cryo-EM studies in our group 🔬🧬. Includes world class training opportunities @EdinUni_IGC @MDC_Berlin. See below for more details and please get in touch if you're interested. https://t.co/le0N4BkGKY

4-year PhD studentship available in my lab to study helper helicase function in eukaryotic DNA replication. Happy to receive any enquiries directly to me. Come join us and add your figure to the lab lego collection! https://t.co/rfy8mH8okn

Great first day of EMBL DNA replication meeting in beautiful Heidelberg, including a hike to the Schloss with @Yeeles_Lab

What a fantastic few days at UK DNA replication 2024 - thanks @BiochemSoc for organising such a great meeting. Hope to see you all in Edinburgh in two years time 🏴󠁧󠁢󠁳󠁣󠁴󠁿

Excellent summary of Tavi and Cristian's recent work. Thanks @JamesMDewar!

CMG helicase disassembly is essential and driven by two pathways in budding yeast Karim Labib and colleagues show that Pif1-family helicases mediate an ancestral pathway for ‘old’ #replisome disassembly during the subsequent S-phase https://t.co/pCwkNuzxgB

Brilliant to see our talented postdoc, Cristian, publish his work on CMG disassembly in @embojournal. The culmination of his PhD work in the Labib lab at @dundeeuni. @TDDeego https://t.co/vRMG6CmLso..

Thanks @mrc_hgu for all the support!

And finally … was also a pleasure to be involved in Cristian and Karim’s work @mrcppu, describing, amongst other things, a new replisome disassembly pathway driven by Rrm3, also out today in @embojournal https://t.co/Baxk3wxHUs

Special well done to our lab’s first ever PhD student Tavi, as well as @simopelliciari and Emma - a real team effort - and @embojournal for an excellent publishing process

Interestingly, the Rrm3 recruitment mechanism we uncovered is largely conserved with the metazoan helicase RTEL1, consistent with the previously suggested functional analogy between Rrm3 and RTEL1

New paper from my group, in which we use the combined power of AlphaFold and biochemical reconstitution to determine how the Rrm3 helicase is targetted to the eukaryotic replisome https://t.co/r6cdK9VvkD

Abstract and early bird deadline for the 2024 UK DNA Replication Meeting is this week. Don't miss out - its going to be a fantastic meeting!

Hope, at last🌹

Today, the country goes to the polls. The nation decides its future. This is our chance to vote for change. We’ve had 14 years of Tory government, 5 Prime Ministers, but the result is the same - decline and chaos. Don’t waste this opportunity. Vote Labour. 🌹

Please RT: The Walter lab at Harvard seeks computational biologists to extend our work using AlphaFold to find new protein-protein interactions. Contact johannes_walter@hms.harvard.edu https://t.co/I5QFibpBbZ https://t.co/4qopg4hSXk

Don’t forget about our UK DNA replication meeting! Only chairs of the sessions invited - rest of the talks are for grabs from the abstracts. Come and share your work with us! #UKDNAreplication