Will Coath
@WillCoath
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PhD student @drcionucl characterising presymptomatic Alzheimer’s disease
London, England
Joined February 2019
Hi #AAIC24 Swing by poster no.4 today (Sunday) to explore age at amyloid onset in the 1946 British birth cohort (Insight 46). Then, find out about estimated time between amyloid and tau PET onset in the cohort on Tuesday 16:15 Ballroom A (3-29-FRS-C). @drcionucl
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Couldn’t have asked for better supervisors and examiners!
Congratulations to @WillCoath on passing his PhD viva exploring amyloid and tau PET in the Insight 1946 birth cohort! Many thanks to examiners Prof @Hammers_Alexand and @PareshMalhotra and fellow supervisors @_michael_scholl and @jmschott
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New preprint out: using data from DIAN, we estimate what sample sizes would be needed for various biomarker outcomes in clinical trials of autosomal dominant Alzheimer's disease
medrxiv.org
INTRODUCTION Alzheimer disease (AD)-modifying therapies are approved for treatment of early-symptomatic AD. Autosomal dominant AD (ADAD) provides a unique opportunity to test therapies in presympto...
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Excited to share the REAL AD design paper, now out in @alzdemjournals The study has been live for 5 months, and we are elated and grateful that 5000 participants have already enrolled! Stay turned for first results! https://t.co/prYcHFeXpT
alz-journals.onlinelibrary.wiley.com
Early diagnosis is crucial to treatment success. This is especially relevant for Alzheimer's disease (AD), with its protracted preclinical phase. Most health care systems do not have the resources...
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EU-MIND Conference is Approaching! ⚠️Don’t Forget to Print Your Ticket! 📩 If you can't find your ticket in your e-mails, please contact us. Thanks!
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This really fascinating new paper by @davecash75 @dave_mri @jmschott et al shows that brain 🧠 regions affected by Alzheimer's disease are also vulnerable to deterioration due to vascular burden independent of amyloid status in cognitively normal elderly. https://t.co/syTJfJQvOH
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🚨Check out our new paper out in Neurology (@GreenJournal): Sex-Dependent Effects of Cardiometabolic Health and APOE4 on Brain Age: A Longitudinal Cohort Study https://t.co/4sjb9FY2gK Summary below👇🏾
neurology.org
Background and ObjectivesThe aging population is growing faster than all other demographic strata. With older age comes a greater risk of health conditions such as obesity and high blood pressure...
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This is going to be an excellent conference - there are still some places available so sign up to hear the latest in European neuroimaging for neurodegenerative disease!
#AAIC24 is over… 🔜 next stop @eumind_congress ‼️ Don’t miss the 1st edition of #EUMIND (EUropean Meeting on Imaging of Neurodegenerative Diseases) All details/info at https://t.co/LK1GLIGaGN We hope to see you in #Caen (Normandy, France) in September (25-27)
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Fantastic talk by @joshkingrobson exploring the effects of midlife shift work on brain pathology 40 years later in the @MRCLHA 1946 birth cohort. Spoiler alert — shift workers have more vascular risk factors, smaller brains but *less* amyloid. More to follow! #AAIC24
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Great talk by @WillCoath using the @MRCLHA 1946 cohort to explore the timing pf and relationship between amyloid and tau positivity with age #AAIC24
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Hello #AAIC2024 attendees. Today I am presenting my work on the association between tau PET and fluid biomarkers in the cognitively unimpaired individuals in the early AD continuum at booth 468. Looking forward to hearing your thoughts. #BarcelonaBeta #ENDALZ
We're halfway through #AAIC24! 👩💼 Come visit us at the poster presentations we have today: 266 - Luis Felipe Hernández 393 - @pati_genius6 409 - @kassinopoulos 468 - @MehrnazShekari 486 - @natvilortejedor 770 - Núria Tort
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I’m over at my #AAIC24 poster 782 this afternoon, which looks at sample sizes for reduction of AD pathology in autosomal dominant AD using PET and CSF as potential outcome measures.
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If you attended @NeuroimagingPIA AIC, please could you 👉🏻 Go to https://t.co/LQ8R9PLO6S 👉🏻 Enter the code #AAIC24 👉🏻 Select the AIC room 👉🏻 Fill out the survey. All feedback appreciated! We all bemoan small sample sizes, so improve ours by telling us what you thought of AIC!
slido.com
Slido is an easy to use Q&A and polling platform. Increase engagement at your meetings, events, and conferences.
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📣 Registrations for the Educational Workshop “Getting Started with Neuroimaging Analysis” are now OPEN AIM: Provide new/early-career researchers #research-ready skills to process #neuroimaging & interpret findings in the context of #aging & #dementia 📅Sept 25, 2024 📌Caen🇫🇷
As part of the EU-MIND congress, we are organizing a pre-conference workshop entitled"Getting Started with Neuroimaging Analysis". The workshop will be held on September 25, 2024 in Caen, France, prior to the start of the conference. Get your tickets:
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📺Watch 'The Jennings vs Alzheimer's' on @BBCTwo tonight at 9pm 📺 Find out how experts, inc. Prof Sir John Hardy, Prof Nick Fox, and Dr @cathmummery @drcionucl have shed light on #AlzheimersDisease, its causes and potential cures, for #DementiaActionWeek
https://t.co/Nwn6E4EX9Q
ucl.ac.uk
A new BBC documentary, The Jennings vs Alzheimer’s, explores the discoveries made by researchers at UCL and UCLH that have given hope for Alzheimer’s disease over the past four decades, and the very
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*Update* — we are now hiring for a study coordinator AND a biomarker research assistant to work on the UCL blood biomarker challenge ADAPT study. Please apply/spread the word. https://t.co/AgEt6THlkg…
https://t.co/AgEt6THlkg…
Great to announce that teams @UCLIoN and @DementiasUK have both been awarded the Blood Biomarker Challenge. The @ucl team will test the diagnostic utility of ptau217 for Alzheimer’s in @NHS memory clinics @alzheimerssoc @AlzResearchUK @NIHRresearch @BBCr4today @UKDRI
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📣 Our course “Biomarkers for neurodegenerative diseases” is now open for registration, and may I say, it gets better every time! It will take place May 20-24 in Gothenburg, completely free of charge. Make sure to secure one of the 50 available places: https://t.co/VSo9wKm44j
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Cortical thinning in regions typically associated with Alzheimer’s may relate to vascular disease! Our latest from @MRCLHA Insight 46 study *open access* in @JNNP_BMJ
https://t.co/aT9XBbmRQE
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We are looking for a highly motivated #postdoc to join our team for an exciting collaborative project on #AI image analysis. The position entails working closely with academic and industry partners in Sweden, the US, the UK and Germany. Please share! https://t.co/C0e0VvUgat
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