Matthew R. Vogt
@VogtVirusLab
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A student of humans and viruses. And sometimes mice. Asst. Prof. of Pediatrics and Microbiology & Immunology @UNC_SOM. Peds ID doc. Tweets are mine.
Chapel Hill, NC
Joined June 2019
This mAb is one we first made @VUMC_Vaccines . For more details, here is the original manuscript describing it (and many others). Glad to see this important step!.
science.org
A human monoclonal antibody shows potential to prevent or treat acute flaccid myelitis associated with enterovirus D68 infection.
NIAID-sponsored trial will assess new #EVD68 therapeutic for polio-like #AFM. Antibody developed from recovering patients. Learn more:
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RT @CCTSI: Our @CCTSI director of Resources and Services, @kmess44 of @COpedsID, led a newly published study with @VogtVirusLab showing how….
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RT @COpedsID: A Commentary by @SCauchemez highlights the importance of population level serologic surveillance, demonstrated by the PREMISE….
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Couldn’t agree more with @kmess44 here. This work is cool in like four different ways. Learning about EV-D68, yes, but also so many more viruses. Strengthening prediction abilities for viruses. And feeding into mAb and vaccine prep. I love it all ❤️.
Leading this PREMISE project w @Peds_Hai_D & @VogtVirusLab has been one of the highlights of my career. So many amazing ppl worked together to generate this novel data from a unique immunoepidemiologic approach to infectious disease surveillance. Excited to share our 1st paper!👇.
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I’m pumped to see this work in print! Congrats to the @hdtbio crew on a very cool EV-D68 vaccine. This was a fantastic way to debut our #AFM mouse model. Glad you brought us on and congrats on getting the cover, to boot!.
🧵 New in @ScienceTM and on the cover! After developing RNA vaccines for several different enveloped viruses, we realized that no one had done so for nonenveloped viruses. In this paper, we sought to do just that, with a focus on a prototype picornavirus.
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RT @NIAIDNews: NIAID-sponsored trial will assess new #EVD68 therapeutic for polio-like #AFM. Antibody developed from recovering patients. L….
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Since they don't link to it in the press release, this is the manuscript describing the mAb if you are interested in a deeper dive:
science.org
A human monoclonal antibody shows potential to prevent or treat acute flaccid myelitis associated with enterovirus D68 infection.
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A long time coming and very exciting: one of our anti-EV-D68 mAbs is entering clinical trials! . NIH-Sponsored Trial of Enterovirus D68 Therapeutic Begins | NIAID: National Institute of Allergy and Infectious Diseases
niaid.nih.gov
The National Institutes of Health (NIH) is sponsoring a clinical trial to evaluate the safety of an investigational monoclonal antibody to treat enterovirus D68 (EV-D68), which can cause severe...
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RT @kmess44: NIAID: NIH-Sponsored Trial of Enterovirus D68 Therapeutic Begins. Years of work by @VogtVirusLab & others have led to the deve….
niaid.nih.gov
The National Institutes of Health (NIH) is sponsoring a clinical trial to evaluate the safety of an investigational monoclonal antibody to treat enterovirus D68 (EV-D68), which can cause severe...
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RT @COpedsID: Ars Technica: The mystery behind the uncoupling of enterovirus D68 #EVD68 and acute flaccid myelitis in the US in 2022, featu….
arstechnica.com
Researchers braced for a surge in 2022 that never came—and no one knows why.
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We are seeking a research tech to help with our human monoclonal antibody discovery efforts, with opportunity for further independent work. Basic science with translational outcomes. Please send the below link to anyone who might be interested. Thanks!.
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RT @_peermentor: Check out this column piece by PMN Co-founder, Taylor Tibbs. She discusses how having a peer network can be a powerful for….
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RT @tayloredsci: In 2020, I created the Peer Mentor Network (PMN) beside other driven grad students/postdocs. @_peermentor @JennyLoome @Jil….
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RT @mbiojournal: @GannaMetzger, @wtjackson, et al. report surprising pH sensitivity findings in the EV-D68 lifecycle, different from poliov….
journals.asm.org
Picornaviruses are responsible for nearly half of all acute respiratory illness (ARI) cases caused by viral pathogens (1). Enterovirus D68 (EV-D68), an emerging respiratory picornavirus, manifests...
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RT @Billicillin: We making plans, y’all!! The IDSA’s LGBTQIA+ interest group #ProudlyID’s leadership getting together to finalize plans for….
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RT @Billicillin: So excited for #IDWeek2023 in Boston!! . Stay tuned for updates on @IDSAInfo’s newly minted LGBTQIA+ Interest Group, #Prou….
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💯.But also get the Global Entry ($100). Well worth it. Your time, not to mention sanity, has value. I don’t know how to properly assign that value, but it’s definitely worth this.
Just a friendly reminder to all my postdoc friends "on the market" get your TSA Pre-check now. its good for 5 years and only 80$ (so like its basically free right?).
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Quick reminder to be kind to your ID pharmacists as these exciting, groundbreaking new therapies come online and we figure out how to best get them implemented. Also, Bill, my daughter is due in November, so I have a quick question about nirsevimab….
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Since not everyone can be interested in viruses (crazy, I know), I also fully endorse the @IPishchany lab! We are thrilled she joined the team at @UNC_SOM Peds ID. Cool science, and a great person to work with, to boot. Do yourself a favor and see what she’s up to.
With the anaerobic chamber installed and my name on the door, it’s officially time to announce the launch of the Hood-Pishchany Lab at UNC Chapel Hill! Follow along if you’re into microbial ecology, vaginal microbiome, sexual and reproductive health! #CarolinaVaginaLab #ShEcology.
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RT @IPishchany: With the anaerobic chamber installed and my name on the door, it’s officially time to announce the launch of the Hood-Pishc….
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