Wai-Leung Ng
@Tufts_NgLab
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Quorum sensing, phage defense, and interbacterial interactions. @tuftsnglab.bsky.social
Boston, MA
Joined August 2015
RT @ashIeyluo: Learn more about BDBS and PREP at the @TuftsGSBS booth (1536) today at 2:30-7pm!. BDBS: PREP: https….
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RT @ashIeyluo: 🧪‼️ UNDERGRADS WANTING RESEARCH EXPERIENCE‼️🧬. The NIH-funded 10-week BDBS Program at Tufts provides a research intensive ex….
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RT @bioetry: Only two weeks left for registration to Vibrio 2024! . Deadline for abstract submission will also close on August 15th so uplo….
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RT @realKarlKlose: Vibriophiles! There’s still time to submit your abstracts to be considered for oral presentations for Vibrio2024 in Lima….
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RT @yisak_w: Excited to share our recent pre-print! The Vibrio cholerae encoded Nezha anti-phage system (SIR2-HerA) restricts virulent vibr….
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RT @bioetry: Registration for Vibrio2024 is now open! . Please kindly spread the word to those that might be interested ♻️. .
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RT @realKarlKlose: MEETING ALERT: Vibrio2024 in Lima Peru Oct 20-23,2024. This is going to be an exciting conference, check out website f….
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RT @TuftsIRACDA: WE ARE HIRING! Currently recruiting for our next cycle beginning 9/1/24 for postdoctoral scholar training positions! Appli….
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RT @erin_r_green: My lab at @UChicago_Micro is hiring! We are looking for a research tech to work with us studying mechanisms of bacterial….
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This is amazing and will be a very useful resource!.
Story time: when I started my postdoc with @WatersLabMSU in August last year, we aimed to use V. cholerae to understand how genetic interactions, including epistasis and pleiotropy, influences its pathogenesis and evolution. 1/18.
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RT @KarinaXavierLab: Please RT! Junior POSTDOC fellowship on Bacterial Quorum Sensing in gut Microbiota funded available in @KarinaXavierLa….
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RT @WatersLabMSU: Proud of work led by @GeoffreySeverin with @Tufts_NgLab and team. Also includes @CinnamonAHHH @hsueh_brian Chris Rhoades….
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Other than @KarinaXavierLab and @Biolluminator many Basslerites (@papenfortlab @Sampriti_M @NinaMolinHK @WatersLabMSU, Jing Yan, Brian Hammer), and many QS experts have contributed to this issue. Personal favorite is from @FuquaClay. Go check it out!.
Summer reading: in this editorial together with @Biolluminator Julia Van Kessel and @Tufts_NgLab Wai-Leung we wrote our thoughts about Bonnie’s @Qsense career and our amazing journal through her lab
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RT @IsbergRalph: Don't miss it! @MartinJLercher and @ItaiYanai interview Bonnie Bassler on NightScience podcast!.
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Like CBASS, Ddm could defend against phage attack with an abortive infection mechanism (see by @MBlokesch's Lab). It makes perfect sense that QS is used to foster an altruistic behavior to achieve population-wide protection (2/2).
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This is again a wonderful collaboration with @WatersLabMSU and @GeoffreySeverin and many others! Not only quorum sensing regulates CBASS, @Hydroxide_ion shows that QS also transcriptionally activates another anti-phage system Ddm in V. cholerae: (1/2).
We just posted a new @biorxivpreprint led by @GeoffreySeverin that shows the CBASS anti-phage defense system of V. cholerae is activated by both quorum sensing and folate depletion! 1/.
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I totally enjoy my mentoring experience in this excellent postdoc training program with @SandraMicrogirl. The application deadline for positions beginning in the fall of 2023 is February 1, 2023. Feel free to also contact me for questions!.
#HIRING! Providing postdocs the skills to succeed in an academic career! Apps due Feb 1 for fall '23 start! - - #science #research #training #teaching #pedagogy #grantwriting #boston #tufts @TuftsUniversity #postdoc #skills #academic #career #succeed
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This is very interesting! In our previous study on VSP islands, @Hydroxide_ion isolated a Ddm-resistant phage with a slightly different DNAP. What could be the role of this polymerase variant in bypassing Ddm?.
Type II Lamassu defense system (also called DdmABC in V. cholerae) is triggered by DNA stem-loop hairpin structures. Structures are suggested to form during phage and plasmid replication from single-stranded or damaged DNA. Interesting preprint from the Mekalanos lab!
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