Tim Brown, MD MSCE
@TimothyJBrownMD
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Asst Prof, GI Med Onc, APD @UTSWcancer via @PennCancer @UPennDBEI @NIH_LRP @UTSWIMchief . Lucas’ dad forever. Views own. ASCO FCOI
UT Southwestern
Joined June 2015
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Pinned Tweet
Immune checkpoint inhibitors are used to treat many types of cancer, but talking with patients about immunotherapy can be confusing.
@Ron_cology
@erin_bange
and I developed a
@JAMAOnc
Patient Page to help clinicians and patients with this conversation.
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Ladies if he:
- is condescending about your methods and results
- Identified a spelling error on page 3 paragraph 2 line 4
- Takes a month to return his reviews
- Requests you cite his most recent paper
He’s not your man, he’s reviewer 2.
Cc
@YourPaperSucks
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394
So excited to announce I’ll be returning to
@UTSWNews
@UTSWHemeOnc
@utswcancer
this July where I’ll be seeing patients with GI cancers, conducting research, and assisting with the fellowship program.
41
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At what point does “next generation sequencing” become “this generation sequencing”?
25
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16 years after starting college and I’m now board certified in medical oncology. Grateful for the numerous mentors along the way
11
2
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It’s been a hell of a year, but getting that email reaffirming my match to
@PennCancer
was what I needed today. I’m still going to be an oncologist 🦀💉
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1
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Hi, I’m an oncologist now!
Penn Heme Onc Fellows grad dinner. Quaker meeting style to honor and thank this amazing class.Residents at the start of COVID & fellowship so disrupted by COVID.
@dhjutsw1
@PennMedicine
@DukeCancer
Univ of MINN
@PennCancer
lucky to recruit from this class.
@TimothyJBrownMD
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7
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After 5 years (3 for residency, 1 as
@UTSWIMchief
, 1 as faculty) my chapter
@UTSWNews
is coming to an end for now. Tomorrow, I’ll wake up and start my next journey in hematology & oncology
@PennMedicine
@PennCancer
. Good vibes appreciated. Let’s Rock
12
0
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Excited to present our poster evaluating the efficacy and safety of the addition of SBRT to atezolizumab and bevacizumab in advanced HCC at
#GI24
. Thanks to
@Salthecancerguy
for the 📸
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10
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Went back and forth on writing anything for a few days. Would rather be on the right side than silent.
1) the trainees are watching/following
2) most of us won’t say anything, for the same reasons the victims didn’t
3) Indiv and inst-level response & culture change needed
#CL
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11
84
Fortunate to receive a
@ConquerCancerFd
Merit Award for some of our work on etiology of HCC and outcomes with first line atezo/bev
#GI23
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3
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Great friend/mentor/colleague
@guptaarjun90
does it again in
@JCO_ASCO
!
Everything comes with a cost, sometimes those costs are hidden. Transparency is 🔑 to patient-centered care.
“The Time Toxicity of Cancer Treatment”
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20
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Out now- my first first-author paper in
@BloodJournal
with
@BabushokLab
@PennCancer
– “Non-steroidal anti-inflammatory drugs as a targeted therapy for bone marrow failure in Ghosal Hematodiaphyseal Dysplasia” 🧵 (1/13)
6
12
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Great news to wake up to! I found out my
@NIH_LRP
was funded through
@theNCI
. Grateful to my mentors Drs Yang, Karasic, Gimotty, and
@Ron_cology
and support from
@PennCancer
and Penn CCEB. Time to get to work investigating factors affecting HCC outcomes
8
2
69
First talk as faculty down! Thankful for those who helped me bounce ideas regarding fellowship research pearls
@Deebacca
@Mat_Angelos
@BenManningMDPhD
@littlejonesmd
7
2
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Instead of debates between republicans and democrats, we should have debates between those who believe contrast-induced nephropathy is real and those who know it isn’t.
#truthy
#truthism
#GodSaveTheBeans
@NephrodisiacMD
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6
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The “gas tank” or resilience of the medical workforce has never really been questioned before. Sure, individual cases of burnout certainly exist. But what we are about to witness is a profession-wide wave of burnout and its effects may last years or decades if unmitigated.
We cannot begin to describe the feeling of leaving a hospital ward full of patients gasping for breath, only to be told that we are making it up.
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🎉 Announcing the
#GI23
Featured Voices! Follow along for expert insights & join the discussion leading up to and during the Symposium. ⬇️
@TimothyJBrownMD
@CathyEngMD
@pashtoonkasi
@PamelaKunzMD
@realbowtiedoc
@mpalta1098
@FlavioRochaMD
@ARosen380
@rachnatshroff
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120
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Started the process of packing to move from Dallas to philadelphia. As excited as I am, this one’s going to hurt
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Excited to give grand rounds for
@UTSWGI
today on Purposefully Designing a Meaningful Research Experience in Fellowship. Thanks for the opportunity
@BenElsberndMD
@ArielAday
@ezraburstein
1
6
49
So happy to have run into this legendary Chair of Medicine today,
@dhjutsw1
. Your mentorship and support is something I will cherish for the remainder of my career. Thank you for all you’ve done (and showing us how to do it the right way). Looking forward to the future!
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1
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Excited to be back for a second year as a Featured Voice for
#GI24
and looking forward to connecting with friends & colleagues. Follow along for my takes on the latest GI Onc research and stick around after the meeting for periodic
#chicken
content and other musings
Announcing the
#GI24
Featured Voices! Follow along for a range of expert insights & join the discussion using the official hashtag:
#GI24
⤵️
@TimothyJBrownMD
@manjuggm
@sepideh_gholami
@OncBrothers
@realbowtiedoc
@ARosen380
@NiuSanford
@rachnatshroff
@helops79
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3
6
47
End of the
#GI24
conference for me. It’s always been the people in this community that make this the best conference. See y’all next year (or sooner)!
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Highlights of the day: seeing old friends
@guptaarjun90
@ShaalanBeg
@timilpatel
, watching mentor crush the stage
@KReissMD
, catching up with
@MadhuEluri
, meeting
@HeumannThatcher
@doctorC369
(and many others!)
#GI23
4
2
47
No place in the world like Parkland. A phenomenal place to train and serve.
I miss Parkland.
I miss her sunrises from the 17th floor, the fireworks from the helipad.
I miss rushing a patient to her theatre. The staff opening instruments while we wheel.
I miss laughing with friends in her hidden chambers, call night family dinners between cases.
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5
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0
2
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Surgical mask was causing discomfort and breakdown behind my ears, making adherence a problem. Solution- wife sewed some buttons on a headband. So much better.
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1
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Last thought from a junior standpoint- if speaking up/out about this story hurts career opps in the future, maybe it’s not something I should be chasing anyways. Values matter
4
3
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How about that! Rucaparib is now in the
@NCCN
guidelines for pancreas cancer as a result of
@KReissMD
phase 2 trial showing potential benefit in pts with BRCA/PALB2 mutations.
@mmwatt02
@PennCancer
@BasserBRCA
3
10
43
Advancements in Systemic Therapy for Pancreatic Cancer - our review out now in
@ASCO
Educational Book with
@MarkOHaraMD
and
@KReissMD
1
13
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2021-2022
@doximity
residency rankings are out. Thrilled to see
@UTSWInternalMed
@UTSWIMchief
ranked
#7
among all programs and
#1
with public hospitals. A testament to the clinical environment and leadership from
@DinoKazi
. Cc
@dhjutsw1
@guptaarjun90
1
8
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On the heels of important work from our
@UTSWNews
colleagues recently published in JCO
@ASCO_Pubs
regarding cancer trial accrual, we are proud to present our work on activating clinical trials at
@UTSWCancer
now out in JCO OP
4
12
41
Good read this morning as recommended by the
@ASCO
@AACR
workshop formerly known as Vail "Tips for Success As an Academic Clinical Investigator"
@StephanieLeeMD
#MCCR
0
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40
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2
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Had a little get-together to catch up and reminisce with
@UTSWIMchief
c/o 2019! So good to see everyone again
@DinoKazi
@KondamudiNitin
@saroja_bangaru
@heatherwolfe
@chc_yek
2
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People with cancer often spend a significant amount of time receiving healthcare. Here we (
@erin_bange
@Ron_cology
@kerrycoughlin
& TIME team
@PC3Innovation
) sought to determine if a text-message based tool could be used to identify those experiencing toxicity of treatment
The use of a text-message based tool to assess for symptoms of immunotherapy toxicity had 100% sensitivity.
@Erin_Bange
@PennCancer
@PC3Innovation
#ResearchLetter
1
6
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2
9
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The clinical trial I have been developing over the last year
@PennCancer
is now listed and live on . Check it out here:
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4
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Out now in The Cancer Journal: The Journal of Principles & Practice of Oncology- my first (and hopefully not last) paper with the wonderful
@KReissMD
@PennCancer
. Our review “PARP Inhibitors in Pancreatic Cancer”
3
6
40
First month of chief fellow down, full of great learning opportunities, the rewarding experience of onboarding new fellows, and curriculum development. Grateful for an awesome co chief, supportive leadership, and amazing faculty
#OncologyFellowship
#impostorsyndrome
3
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Excited to share this
@JAMAOnc
#patientPage
on
#PallitiveCare
It’s open access and free to print and share as a patient resource! Please RT/share
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Just submitted my first grant proposal as faculty. S/O
@Deebacca
@ShaalanBeg
@SyedKazmiMD
for reviewing drafts and improving the proposal.
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There is no rational argument for not paying housestaff at least $100k. ESP not while NP/PA with a fraction of the education/debt/responsibility make more than that straight out of school
Residents should make a 6 figure salary
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First year heme/onc fellowship tip: the only way to get the right dose of hydroxyurea is to say it with confidence.
@DrAndyMatthews
@guptaarjun90
@ShaalanBeg
@kansagraMD
5
0
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It took a whole year but our entire fellowship class was finally able to get together…. Without any phone coverage or pandemic worries!
#TeamYeehaw
@PennCancer
3
1
37
COSMIC-312 has now reported out in
@TheLancetOncol
, comparing cabo/atezo to sorafenib in HCC. Cabo/atezo failed to improve OS compared to sorafenib, which had a median OS of 15.5 months, whatttttt? (short 🧵)
2
10
36
For new followers for
@ASCO
#GI23
, welcome! A little on my background:
-originally from ☀️FL
- UG
@virginia_tech
🦃
- MD
@PennStHershey
🍫
- res/CMR/faculty
@UTSWIMchief
@UTSWInternalMed
🤠
- fellow/fmr chief fellow
@PennCancer
🦀
-MSCE
@UPennDBEI
📈🧑💻
Joined 🐦 2015
2
1
35
Today is my last day on solid oncology consults as a fellow at
@PennCancer
. It’s wild that this is coming to an end. Let’s gooooooo
3
0
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Some people hate the Valley of Despair when writing. That period of time when you question everything and can’t stand to look at the paper. Keep pushing, greatness lies ahead. Let’s freakin crush it today.
3
4
35
Every time I sit down to write a brand new paper it feels like I’ve never written a word in my entire life
0
5
34
Out now (eh a few days ago) in JCRCO – part of my thesis
@UPennDBEI
@PennCancer
@PC3Innovation
@Ron_cology
Karasic, Gimotty, and Yang “Outcomes of hepatocellular carcinoma by etiology with first‑line atezolizumab and bevacizumab: a real‑world analysis” 🧵
2
9
34
The wisest presentation at the
#ecancerchoosingwisely
has just been made by the youngest man here
@guptaarjun90
. Watch out world, this young oncologist is going to be a superstar of oncology very soon. Proud of him! 👏👏👏
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0
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An impromptu former and current
@UTSWIMchief
gathering!
@dhjutsw1
@DinoKazi
@KondamudiNitin
@NeilKeshvani
3
0
33
Welcome to headband 2.0. Several upgrades: second button to keep mask earloop completely off ear, darker blue to match scrubs, brighter buttons so purpose is more obvious to pts. Swoosh is only for looks though
1
2
33
Gettin kinda chiefy up in here boys let’s do one for the bird app.
@UTSWIMchief
@NeilKeshvani
@KondamudiNitin
@dhjutsw1
@DinoKazi
0
0
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Flights and hotel booked,
@ASCO
#GI23
bound soon!
#GIOncTwitter
- what are you most excited about with this meeting?
@KReissMD
@MarkYarchoan
@marklewismd
@ShaalanBeg
@guptaarjun90
3
4
33
Great memory today from my iPhone. I believe this was the last day of
@dhjutsw1
legendary leadership as Chair at
@UTSWInternalMed
. Admittedly….I might have let the beard get out of control
0
1
33
Day 1 of
#ASCO21
- check out the results of our phase 1 study in colorectal cancer patients evaluating the combination of regorafenib, hydroxychloroquine, and entinostat.
1
2
33
Shocking report from
@theNCI
that out of pocket costs for patients seeking cancer care were an astounding $16 billion in 2019!! This is not sustainable.
@dhjutsw1
@guptaarjun90
@ravi_b_parikh
@Ron_cology
@erin_bange
h/t
@PC3Innovation
1
18
32
Really don’t know why 2000 of y’all follow me but I’m glad you’re here to read my ramblings on oncology, raising chickens, lifting weights, and the cybertruck (worst truck of all time)
#ImpostorSyndrome
3
0
32
It’s
#ASCO18
week! If that doesn’t excite you, you may need to check if you still have a pulse
0
12
32
I had plans to go to the gym today. Slept in and ate pizza instead. No regrets.
#NightShift
#Wellness
4
0
31
Had the opportunity to do a little professoring today with the fellows. Bad day for gastric cancer
1
1
32
Am I up early because it’s west coast time or am I up early because I’m excited for liver, pancreas, and biliary day at
#GI23
?
@ASCO
#GI23
day ✌️let’s do this!!
@CathyEngMD
@pashtoonkasi
@PamelaKunzMD
@realbowtiedoc
@mpalta1098
@FlavioRochaMD
@ARosen380
@rachnatshroff
@KReissMD
0
5
31
The
@UTSWInternalMed
residency is up to
#7
. Truly speaks to leadership under
@DinoKazi
and
@dhjutsw1
for creating a supportive yet academically rigorous program.
@UTSWIMchief
@UTSWNews
.
#SWIMstrong
The
@doximity
2019 rankings are out and
@UTSWInternalMed
just continues to rise! Number 7 in the US! All thanks to our incredible leadership 💪🏼🙌🏼
@UTSWNews
@UTSWIMchief
@dhjutsw1
@DinoKazi
1
12
43
0
6
30
Happy to share the recent publication of my first clinical trial! Out now in
@OncJournal
featuring
@KReissMD
,
@RyanCMassa
and led by non-twittering Drs Karasic and O’Dwyer
🧵
6
1
31
Dr Cox has me ready to run through a wall with this speech. Congrats
@UTSWSurgeryLife
Last night, our amazing chiefs graduated from
@UTSW_Surgery
via
@zoom_us
. It’s hard to imagine what is normally a 200 person celebration condensed down to a virtual, more isolating experience. Thankfully,
@JohnCMcGinley
brought us joy, humor, and some
#scrubs
wisdom.
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2
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Excited to be a part of this outstanding group. Grateful for support from
@ASCO
@ConquerCancerFd
and to
@KReissMD
& the GI onc group
@PennCancer
for the mentorship.
@dhjutsw1
@erin_aakhus
@lynn_schuchter
@ShaalanBeg
@DinoKazi
This year, we’re pleased to recognize 151
#oncology
professionals with Merit Awards for advancements in
#cancerresearch
, including Justin Barnes, MD, MS (pictured) of
@WUSTLmed
.
0
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0
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Not me furiously refreshing my email awaiting
@ASCO
abstract decisions.
#ASCO22
@KReissMD
@ShaalanBeg
@erin_bange
@dhjutsw1
1
1
31
New paper out today in
@JCO_ASCO
Precision Oncology. “Next-Generation Sequencing Directs Therapy and Delineates a Clonal Relationship in Mast Cell Sarcoma and Acute Myeloid Leukemia”
#leukemia
#cancer
#PrecisionMedicine
2
8
30
This is probably the most misleading a story title could be without being a lie. Story is about midazolam for patients on ventilators. It could certainly be worded better than this
@NBCDFW
3
2
29
Hard to believe
@AliAlqahtaniMD
is a fellow after that masterful presentation on HER2 expression and the tumor immune micro environment!
#GI23
1
6
30
The Torrey Pines sunset was fine but I’m glad to be back in Texas
1
1
30
Fell on the ice outside my house today. That moment of self-reflection that occurs while you’re laying on the ice after a fall re-evaluating your life choices is unmatched.
2
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On the consult service this week, but first we spend time with the Iron
7
0
29
Our latest in AJCO. Nothing new here, but just solidifying years of data that neutropenia diets don’t accomplish what they’re supposed to accomplish. Stop doing them.
2
12
26
Looking forward to sharing our work further describing post-progression therapies and outcomes for BRCA-related pancreas cancer. Great work
@BaqirJafryMD
#ASCO24
@ASCO
@Salthecancerguy
@KReissMD
@SyedKazmiMD
Humbled to share my research on post-progression therapies for BRCA-related pancreatic cancer got accepted for presentation at
#ASCO24
! Immense gratitude to my mentors
@SyedKazmiMD
@TimothyJBrownMD
@Salthecancerguy
@KReissMD
for their unwavering support!
@utswcancer
@AKUGlobal
5
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1
3
26
EA 2192 is officially open
@utswcancer
! Enrolling patients with resected pancreatic cancer and a pathogenic BRCA1, BRCA2, or PALB2 mutation. See more below
@Salthecancerguy
@SuzanneColeMD
@SyedKazmiMD
@littlejonesmd
@ShaalanBeg
@aguilera_md
@eaonc
2
12
28
The most interesting thing about this map is how closely it resembles the distribution of wealth in Dallas county - see next tweet
@dhjutsw1
@UTSWIMchief
@Drjulietmd
@Pranavi_MD
@sandeepdasmd
@Sandi_L_Pruitt
4
2
26
Happy
@ASCO
Annual Meeting abstract submission deadline day everyone! May your abstracts come in at just under 2600 characters, not including spaces
0
5
28
Durvalumab and tremelimumab now approved by
@FDAOncology
@US_FDA
for management of unresectable HCC. Great to have another first line option available for these patients who previously had few treatments available
2
11
27
@esinghimd
@JackWestMD
@DrJNaidoo
@jillfeldman4
@OncBrothers
@AnaVManana
@ADesaiMD
@FawziAbuRous
@drRTee
@jrheum
We made a patient page to help with the conversation that I print and give to patients while discussing
@erin_bange
@Ron_cology
1
6
27
The red used to hurt. Now I welcome the red. If there’s no red, I question if it was read.
@guptaarjun90
@ShaalanBeg
@KReissMD
@dhjutsw1
A mentor’s love for their trainees can be measured in tracked changes
272
2K
14K
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0
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Looks like
@UTSWNews
next move will be south Dallas. Brilliant example of meeting people where they are.
@dhjutsw1
@UTSWIMchief
1
7
27
On the outside we may be cool, but on the inside we have had a years-long blood feud regarding the cybertruck and its place in society.
@ShaalanBeg
3
1
27
So excited to announce that I’ll be training
@PennCancer
for heme/onc fellowship. Beyond grateful for the opportunities I’ve had and wonderful mentors I’ve met at both
@UTSWNews
and
@PennStHershey
! Too many to name but esp
@DinoKazi
and
@dhjutsw1
!!
3
0
27
Have to love the direction of the
@UTSWInternalMed
residency program under
@DinoKazi
. Unparalleled training environment and a program that values you as a person.
@thomasjwang1
@dhjutsw1
The perfect epilogue to an incredible week -
@DinoKazi
's weekly update takes on high-value residency training: "Value = Outcomes that Matter to Residents/Costs Borne by the Resident....the triple aim of such residency training:
1
1
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1
1
26
Squeezed in a little
@PennMedicine
Department of Medicine research symposium in between clinic patients
@PennCancer
@PC3Innovation
@KReissMD
@MarkOHaraMD
0
1
26
Who’s going to do the hip hop references while
@rachnatshroff
presenting the SWOG1815 data??
@CathyEngMD
@pashtoonkasi
@PamelaKunzMD
@realbowtiedoc
@mpalta1098
@FlavioRochaMD
@ARosen380
@KReissMD
#GI23
5
2
25
Just read the faculty email from
@thomasjwang1
. UTSW is truly a special place to have leaders such as
@DinoKazi
@paulk_mi
@rosie6146
@KerryDunbarMD
@DoctorDaleMD
@Scielzo
invested in social justice and health equity.
@UTSWIMchief
@dhjutsw1
1
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