Debabrata Laha
@TheLahaLab
Followers
765
Following
1K
Media
5
Statuses
579
Assistant Professor, Dept. of Biochemistry, Indian Institute of Science @iiscbangalore. Cell Signaling, Inositol Phosphates. Former @MRC_LMCB, @ZMBP_Tuebingen.
Bangalore, India
Joined December 2021
Really delighted and humbled to see that we made it into the cover of Nature Chemical Biology @nchembio! This is first time for us. Kudos to @Priyans73221614 ,@_Riya_Ghosh and Paulami for preparing the cover art. Please see details in PMID: 40745478. @iiscbangalore , @BICS_IISc
Our November issue is live! https://t.co/dU6JE66vS0 The cover depicts a SEM image of a dorsal surface of liverwort M. polymorpha female thallus. Liverwort were found to have a noncanonical pathway for the regulation of master growth repressor DELLA.
20
7
94
Please see coverage of our work by the Kernel @iiscbangalore that we recently published in @PLOSGenetics ! @BICS_IISc @iiscbangalore @DBTIndia @EduMinOfIndia
IISc researchers, in collaboration with the University of Freiburg, found that a tiny molecule, 4/6-InsP7, helps switch on plant “heat-protection” genes. This mechanism, conserved across land plants, could lead to more resilient crops. @TheLahaLab Read: https://t.co/ZfHjhQ1sGU
0
0
13
Two incredible cover stories in one week from my amazing colleagues at our department! One featured in EMBO Journal, and the other in Nature Chemical Biology. Such inspiring science and remarkable teamwork! #Proud #Inspiring #Science Congrats @syncellbiolab and team
Thrilled to be on the cover of @embojournal Odin rises from the Odinarchaeota yellowstonii genome, holding FtsZ1 and FtsZ2 the ancestral twins of tubulin highlighting their evolutionary divergence in Asgard archaea. 👉 https://t.co/kJZwSt8YA1
#archaea #evolution #cytoskeleton
4
3
31
Congratulations to DL Lab on making it to the cover image.👏😃 For details, see below. To read the paper, click: https://t.co/GvI1fSwSsR
@Priyans73221614, @_Riya_Ghosh, @paulami_koley @ @TheLahaLab
2
4
25
Thank you so much Ajay for being great host! It was really wonderful meeting with all of you after long time. I learned a lot during the interactions. Great to see an enthusiastic team.
Wonderful to have @TheLahaLab @iiscbangalore at @NABI_India ! We had fantastic presentation by him followed by great discussion with lab people.
0
0
13
Happy to see highlights of our work, recently published in @PLOSGenetics, nicely covered by @NatureInd! Thank you @NatureInd. @BICS_IISc @iiscbangalore @DBTIndia
🌿 A study by @iiscbangalore and University of Freiburg reveals an ancient molecular pathway — powered by inositol polyphosphate kinases — that helps plants sense and survive heat stress. 🔗 Find out more: https://t.co/FvvTHYG88c
#NatureIndia
1
2
28
We invite you all to attend today's colloquium by Ms. Jyothi. For details, see below:
0
1
8
This year, BICS organised a fun-filled trip to a resort🥳🌿🪴🌴 A day packed with fun games, good food, and sweet tunes🎶. Thanks to everyone who joined and the BICS team for successful planning. Grateful for the memories and laughter we shared together! #BICStrip #GoodVibesOnly
0
3
15
Another study from the lab,🥳☀️ read here, shows how the small molecules inositol pyrophosphates regulate heat stress acclimation in plants by integrating into complex signalling networks🍀🌿. Fabulously executed by my senior @Ranjana84142377. Many congratulations.👏😃
Our work on identification of non-archetypal activity of IPK2 in generating inositol pyrophosphate 4/6-IP7 and regulating heat stress acclimation conserved in land plants, now out in @PLOSGenetics, spearheaded by very talented Ranjana @Ranjana84142377
https://t.co/wNK55RsIz8
0
2
10
Today, we welcome Prof. Ramesh V. Sonti, Director @ICGEBNewDelhi, for the Dr. NUGGEHALLI NARAYANA MEMORIAL LECTURE in the Department of Biochemistry. Please join us as he delivers his talk on "A bacterial effector bridging plant and bacterial signaling" For details, see below:
0
2
17
Many thanks to Priyanshi and Jyothi for their important contributions, and whole lab for the support. We are grateful to the editor and reviewers for their critical and constructive feedback! @iiscbangalore, @DBTIndia , @ANRFIndia,@BICS_IISc for funding and support!
0
0
2
We are grateful to Guizhen Liu, Danye Qiu and Henning J. Jessen @UniFreiburg for the excellent CE-MS analyses and wonderful collaborative efforts!
1
0
3
Our work on identification of non-archetypal activity of IPK2 in generating inositol pyrophosphate 4/6-IP7 and regulating heat stress acclimation conserved in land plants, now out in @PLOSGenetics, spearheaded by very talented Ranjana @Ranjana84142377
https://t.co/wNK55RsIz8
journals.plos.org
Author summary Inositol pyrophosphates (PP-InsPs) are eukaryote-specific cellular messengers that control a plethora of critical physiological processes, ranging from cellular metabolism to cellular...
20
10
59
5 years of pipetting, countless experiments, plenty of caffeine with one amazing lab family, Cheers to science. Happy foundation to my dear Lab. 😃🥳👏🍀☀️✨💫
2
1
119
A detailed protocol to monitor inositol phosphate profile in Marchantia and other land plants from our lab. Wonderful efforts by Priyanshi and Riya!
Happy to have contributed to a newly published protocol as a part of the book series in Methods in Molecular Biology (MiMB). #Marchantia #HPLC #InositolPhosphates Thank you @TheLahaLab and @Priyans73221614. Read here: https://t.co/qnbapUMBG8
1
1
16
"Jana Gana Mana" is the national anthem of India, originally composed in Bengali by poet Rabindranath Tagore, who was awarded the Nobel Prize in Literature in 1913. Pictured: An English translation of Jana Gana Mana by Tagore
191
3K
18K
🎉🍾Excited to share our #Asgardarchaea #odin #cytoskeleton study published in @embojournal Dual FtsZ proteins in Odinarchaeon form distinct filaments—shedding light on tubulin/FtsZ evolution. Brilliantly led by @Jayantikri23
https://t.co/nhj4xfNM1A
Thrilled to share our lab's first evolutionary cytoskeleton study! We uncover two distinct FtsZ paralogs in Odinarchaeota—OdinFtsZ1 forms curved filaments, while OdinFtsZ2 assembles into spiral rings. A glimpse into tubulin evolution! #Eukaryogenesis #AsgardArchaea #cytoskeleton
38
20
119
A snapshot of the mechanics shaping organs: what plants and animals can teach each other. Thank you @MabelMathew_M @Stanford and @Dash_Ankita @IISERPune for putting this together. @DBTIndia , @serbonline
1
14
35
Do we know whether non-human mammals enable the human adaptation of 2.3.4.4b #H5N1 to establish human infections? Excited to share our study, published now, addressing this question. #AvianInfluenza
@iiscbangalore @RanjanaNataraj @avinashkarkada
https://t.co/biqi2uTmM7
journals.asm.org
The 2.3.4.4b clade H5N1 virus emerged as a panzootic strain, leading to the unprecedented deaths of domestic and wild birds and diverse non-human mammalian species. Intriguingly, the 2.3.4.4b H5N1...
21
8
56
Great work by Srimonta and entire team! Many congratulations
Published now @genomeresearch how Xist upstream elements regulate gene expression. Excellent work by @SudeshnaMajum18 Thanks @iiscbangalore @ANRFIndia @DBTIndia @EMBO_YIP for support. https://t.co/CFkuOi57wx
1
1
4