Tacke Lab
@Tacke_lab
Followers
681
Following
58
Media
29
Statuses
126
Research group studying liver immunology and gut-liver interactions, acute and chronic liver diseases. #liver #immunology #immunooncology #inflammation
Charite Berlin, CVK
Joined September 2019
🙌 This review summarizes recent findings deciphering the relevance of liver macrophage spatial localization as a phenotypical marker and functional contributor to liver diseases. via https://t.co/h0GDWVFVdP
@bmj_company @Tacke_lab @FrontGastro @FrankTacke
0
3
5
A review paper by Prof Frank Tacke & Dr Adrien Guillot entitled ‘Spatial dimension of macrophage heterogeneity in liver diseases’ via https://t.co/UzIWeigwnc
0
4
12
Now in the latest Hepatology issue! Thanks to all contributors and collaborators! https://t.co/AKvyob1l8n Multiplex immunostaining revealed that accumulation of IBA1+ CD16lo CD163lo macrophages near ductular cells is a hallmark of advanced liver disease (incl. NAFLD, PSC).
1
9
38
What are the mechanisms of fibrosis across organs and disease etiologies? 💡Our latest review examines the underlying processes and resulting therapeutic opportunities. @ILurje
https://t.co/2YGF6uGIsA
0
4
12
Ever wondered why CXCR6+ cells in the liver are important? Check out our latest article showing that loss of CXCR6 exacerbates inflammatory IL17 responses in liver! Hepatic C-X-C chemokine receptor type 6–expressing innate... : Hepatology Communications
journals.lww.com
eloid cells are early drivers of liver inflammation. However, the role of the abundant population of liver-resident innate lymphocytes, which commonly express the chemokine receptor CXCR6, is...
0
1
22
Check-out two recent reviews from our department and collaborators on the diverse roles of immune cells in primary liver cancers! Big-up to #MarleneKohlhepp
@Branden_HY_Liu @YeniAit #FouadLafdil #AdrienGuillot @Tacke_lab 📌 https://t.co/3q6jDtgDmW 📌
0
0
6
Happy #WomenInScience Day! So greatful for this team of powerhouse woman scientists that slay every single day. Let's keep this going @ILurje @JohannaKusnick and the whole twitter-less bunch @Tacke_lab
0
3
11
Congrats to our PI #AdrienGuillot advocating for science and research! Hooray for the Franco-German friendship! #GenerationEU @ofaj_dfjw @AllemagneDiplo @EmmanuelMacron @Bundeskanzler
0
1
15
We are thrilled to announce that the members of our lab Adrien Guillot and @ilurje together with Prof. Fouad Lafdil will edit the Special Issue "Tumor-Associated Macrophages in Primary Liver Cancers and in Premalignant Liver Diseases". We look forward to your submissions!
0
3
7
Just some of our rising stars (@JohannaKusnick AlixBruneau) having fun presenting their data at the annual meeting of @Ferroptosis2306 #ferroptosis #immunogeniccelldeath #curinglivercancer
0
1
11
Happy and proud to fond our name here again this year #HighlyCited2022
https://t.co/3jJFMOZEYf this is a team effort!!
clarivate.com
The Highly Cited Researchers 2025 list identifies and celebrates individuals who have demonstrated significant and broad influence in their fields of research. Through rigorous selection criteria and...
Congrats to all #HighlyCited2021 Researchers at #CharitéBerlin! Proud and happy to find our name on this list 🤗
1
1
6
Congratulations @CorneliusEngel7 !
🆕Article in press❕ Combination of G-CSF and a #TLR4 inhibitor reduce inflammation and promote regeneration in a mouse model of #ACLF Read it here👉 https://t.co/ZG9wQwr1Mn
@CorneliusEngel7
#LiverTwitter
1
0
9
#Cover: Distinct histopathological phenotypes of severe alcoholic hepatitis: https://t.co/JRMKhYi6Qp Image: multiplex immunofluorescence staining of liver tissue with SAH, revealing a large number of inflammatory cells surrounding hepatocytes @NIAAAnews
#Gastroenterology
0
0
5
Our collaboration with Bin Gao’s lab just released in JCI: two distinct histopathological phenotypes based on liver immune phenotyping observed in severe alcoholic hepatitis patients Our multiplex IHC is on the cover @Tacke_lab #AdrienGuillot @NIAAAnews
https://t.co/EgBv7ZY2LD
1
0
10
Delighted to see our review on immune cell heterogeneity in #NAFLD in the era of multi-omics in press at @JHepatology! Thanks to invaluable contributions from @CancerInflam, @RobSchwabe, @Kubes_Lab, Jochen Hampe and of course @Tacke_lab! #LiverTwitter
🆕Review❕ Immune mechanisms linking metabolic injury to inflammation and #fibrosis in #fattyliverdisease – novel insights into cellular communication circuits By @moritzpeiseler & colleagues Read it here👉 https://t.co/MCEm5Vbdb6
#LiverTwitter
1
8
27
Read now in „Liver Cancer“: ❗️single-nucleotide polymorphism of CXCR1 is associated with oncological and overall outcome in surgical CCA patients❗️ https://t.co/9QGplQuk8b
@glurje @ZoltanCzigany @Tacke_lab @ChariteBerlin @KargerPublisher
karger.com
Abstract. Background: Perihilar cholangiocarcinoma (pCCA) is a rare primary liver malignancy. Even in patients amenable to surgery, outcomes are often dismal. Here, we aimed to identify prognostic...
1
2
10
Our master's student just won a speed lecture award talking about her research studying #ferroptosis in #livercancer. So proud!! Congrats @JohannaKusnick @Tacke_lab @Ferroptosis2306 #BIONNALE #fireuptheliver
Starker Auftritt, sagt #vfabio: Johanna Kusnick @ChariteBerlin gewinnt den #BIONNALE #SpeedLectureAward 2022, gesponsert von @HealthCapitalBB und #vfabio @vfapharma.
2
3
25