Simone Immler
@SimoneImmler
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Professor of Genetics and Reproduction @biouea Founder and Scientific Director of Virilitas Labs Ltd https://t.co/PjwMR9e6Hu
University of East Anglia, UK
Joined August 2014
We had a great end to 2024 publishing: . The Zebrafish Sperm Proteome.. We described >5400 sperm proteins generating a great atlas for future work!. Spearheaded by PhD student @JaymeCohenBIO with great collaborators at @biouea and @JohnInnesCentre.
analyticalsciencejournals.onlinelibrary.wiley.com
One of the key processes that forms the basis of fertilisation is the tight interaction between sperm and egg. Both sperm and egg proteomes are known to evolve and diverge rapidly even between...
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This is a simple parsimonious model to explain the evolution of lifespan extension by dietary restriction and other forms of stress that suppress fertility. Happy to be part of this exciting study!.
1/8 . Why does eating less extend lifespan? 🧬. We often think about saving energy or recycling waste - but we show how evolution acting on mutation load can generate longer life on low food 🧵. and preprint below:. 🔗
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RT @AliceGodden: 🚨Our new paper @SimoneImmler .FishPi: a #bioinformatic prediction tool to link #piRNA and #transposable elements .Read no….
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RT @SimoneImmler: We had a great end to 2024 publishing: . The Zebrafish Sperm Proteome.. We described >5400 sperm….
analyticalsciencejournals.onlinelibrary.wiley.com
One of the key processes that forms the basis of fertilisation is the tight interaction between sperm and egg. Both sperm and egg proteomes are known to evolve and diverge rapidly even between...
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RT @AliceGodden: 🚨 Happy to share my latest preprint on #polarbear #transposon activity in response to diverging climates in #Greenland #TE….
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RT @AliceGodden: 🚨Pleased to share our latest preprint on #zebrafish #geneexpression and #transposons in #sperm & #embryos exposed to socia….
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I finally caved and am now on bluesky - help me finding you and follow me there @immler.bsky.social and send me starter packs!. Thank you!.
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RT @AlexeiMaklakov: We have PhD position advertised in evolution of ageing with Tracey Chapman and @SimoneImmler:. Please contact me if you….
aries-dtp.ac.uk
Professor Alexei Maklakov, Biological Sciences, University of East Anglia – contact me Professor Tracey Chapman, UEA BIO Professor Simone Immler, UEA BIO Why do organisms age?
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RT @jennyperry: Why is there so much diversity in male seminal fluid proteins?.Funded PhD position available with Tracey Chapman @biouea .R….
biodtp.norwichresearchpark.ac.uk
CHAPMAN_U25DTP2
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RT @SimoneImmler: I am also incredibly proud of this preprint:. Gum Arabic (Acacia senegal) enhances reproduction and modulates the microbi….
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RT @DrDanielMarcu: Incredibly excited to share our preprint ( from.@SimoneImmler’s Lab 🥳!. By harnessing genomics,….
biorxiv.org
Males produce millions of sperm in a single ejaculate, but only a single sperm fertilises the egg. Fertilisation is the perfect opportunity for natural selection where sperm of poor quality are...
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RT @SimoneImmler: I am incredibly proud of this paper in preprint: . Within-ejaculate haploid selection reduces disease biomarkers in human….
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I am also incredibly proud of this preprint:. Gum Arabic (Acacia senegal) enhances reproduction and modulates the microbiota-gut-brain axis. Again a massive team effort by @Ko0L_J_ @asdfjohnny @AliceGodden @JaymeCohenBIO et al!
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Selection within the ejaculate of men results in genetic changes in key genes involved in neurodevelopment, cell signalling and cell proliferation and that the 'fitter' sperm in an ejaculate exhibit reduced expression of biomarkers for neurodevelopmental disorders and cancers.
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I am incredibly proud of this paper in preprint: . Within-ejaculate haploid selection reduces disease biomarkers in human sperm . It has been long in the making and has been a true team effort! . @danielmarcu @JaymeCohenBIO @AliceGodden @GAlavioon et al!
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RT @AlexeiMaklakov: Germline removal benefits males more than females - led by @martin_i_lind in @AgingCell : (see….
pubmed.ncbi.nlm.nih.gov
Classical evolutionary theories propose tradeoffs among reproduction, damage repair and lifespan. However, the specific role of the germline in shaping vertebrate aging remains largely unknown. In...
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RT @AlexeiMaklakov: Reduced insulin/IGF-1 signalling upregulates two anti-viral immune pathways, decreases viral load and increases surviva….
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RT @SimoneImmler: I am very happy to announce the recent publication of a beautiful theory paper with @mscott0106 and Karl Mackintosh (not….
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RT @OmarRawi89: Merger of NYRA @YoungAndrology with @EAAndrology is highlighted in this society news article published in Andrology 🤩. http….
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I am very happy to announce the recent publication of a beautiful theory paper with @mscott0106 and Karl Mackintosh (not on X) on the interactions between mating system evolution and haploid gametic selection in @PLOSGenetics .
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