
Amanda Sierra
@SierraLabAch
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Sierra Lab: Neurobiologists. Microglial lovers. Science communicators. Personal stuff: @AmandaSSaavedra Now at [email protected]
Joined December 2018
Happy to share our Perspective on #microglia #pruning and help to answer the questions of whether they are hunters or gatherers of brain #synapses .
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RT @MicrogliaSeries: ⬇️This is happening today⬇️.And it is not going to be recorded, so see you all there!.
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The intriguing FIRE mice, hmmmm!.
📢 New webinar coming soon 📢 .Clare Pridans from Institute for Regeneration and Repair, University of Edinburgh @MedEdin will be our next speaker on June 3rd. Check all the information in the flyer and add it to your calendar!
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RT @COSCEorg: La Confederación de Sociedades Científicas de España (COSCE), en colaboración con la @FundacionAreces, otorgará el Premio COS….
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Don't miss it! Superb imaging and cool data on microglia-matrix interaction!.We are sorry we had a last minute cancellation from the scheduled speaker.
📢 New webinar coming soon 📢 .There has been a schedule change for tomorrow: Federico Soria @SoriaFN, expert in matrix-microglia interactions, will be our next speaker on May 6th (tomorrow!). Check all the information in the flyer and add it to your calendar! @AchucarroGlia
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RT @MicrogliaSeries: 📢 New webinar coming soon 📢 .Prof. Steffen Jung from @WeizmannScience will be our next speaker on April 1st. Check all….
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RT @COSCEorg: COSCE apoya las reivindicaciones de los investigadores en IA sobre la convocatoria anulada. “Imagina si lo comparamos con una….
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RT @maxplanckpress: More than 40 percent of #postdocs leave academia. Those who landed a coveted faculty position were more likely to have….
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Any #SpatialTranscriptomics people out there interested in studying #microglial development?.We need a collaborator based in the Americas or Asia to apply for a #HSPF grant.
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RT @NatureNeuro: A Perspective from @SierraLabAch on #microglia as hunters or gatherers of brain synapses.
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RT @COSCEorg: Ante la cancelación por parte del @CienciaGob de la convocatoria de ayudas a la IA, COSCE ha hecho público el siguiente comun….
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RT @Cunningham_Colm: Extended deadline to Jan 31 (now with broken link replaced!) .We're looking for a talented & motivated Neuroimmunology….
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I think the field needs to start reconsidering #microglia as The single most important mediator of #SynapticPruning, a widespread concept. We offered our Perspective on whether microglia are hunters or gatherers of brain synapses here.
Mice lacking microglia (Csf1r∆FIRE/∆FIRE) have normal.-synapse number and maturation.-seizure susceptibility and hippocampal-prefrontal cortex coherence.-segregation of inputs into the lateral geniculate nucleus.-neuronal and astrocytic gene expression.
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More evidence in favour of microglia as synapse gatherers, not hunters, as we discuss here.
Typical development of synaptic and neuronal properties can proceed without microglia in the cortex and thalamus @NatureNeuro .
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RT @MatthewZipple: Excited to share our article, out today in @ScienceMagazine showing that competition amplifies the role of early life lu….
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Great lab for a PhD project!.
WE ARE HIRING!!.Looking for a PhD project? Neuroscience lovers, this is your place! Apply now!!! Deadline is 28/12/2024 👌.@InstitutoCajal @SENC_ @CSIC @CSICdivulga @FENSorg.@PilarQuijada3.@DNeuro_UPO @ucc_complutense .@master_uc3m @UAM_Madrid @UABBarcelona
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