Shahnawaz Amdani
@ShaanAmdani
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Section Head,Pediatric Heart Function/Tx @ClevelandClinic. This is my calling, not my job. Be kind, help & love all humans. Learning never stops. Tweets my own.
Cleveland, OH
Joined March 2013
We studied heart transplant outcomes for 1352 patients with Fontan circulation and what did we find? Key takeaways 🧵: @JCardFail @HFSA @robmentz @dranulala @ShashankSinhaMD @CleClinicHVTI @PHTSociety @EstelaAzeka
https://t.co/FkmO38XBPJ
onlinejcf.com
Pediatric patients with Fontan circulation represent a growing, high-risk cohort of heart transplant (HT) candidates. However, contemporary multi-institutional data on their waitlist and post-trans...
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7. Risk factors for mortality among Fontan patients: Waitlist : being in-hospital, mechanical ventilation, ECMO, renal dysfunction , urgent listing Post-HT: ECMO, Black race , older donor, renal dysfunction.
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6. Patients with a Fontan circulation with elevated PRA (>10%) are at higher risk of experiencing rejection.
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5. Patients with Fontan circulation are also more likely than cardiomyopathy patients to experience infection and malignancy.
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4. Post-HT survival for Fontan patients has improved overall, they continue to experience increased mortality compared to patients with CMP. Patients with a Fontan circulation undergoing HT are 2x as likely to die compared to CMP patients.
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3. Waitlist survival for patients with a Fontan circulation has improved and is currently ∼90%. No different than those with non-Fontan CHD or cardiomyopathy.
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2. Fontan patients are 6 times less likely than cardiomyopathy patients to undergo VAD implant! However, VAD supported Fontan patients have outcomes similar to non-VAD supported patients and significantly higher than those supported on ECMO.
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1. There has been a rise in the number of patients with Fontan circulation listed for HT and they represent the most common cohort of CHD currently listed for HT.
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Throwback Thursday: @PHTSociety analysis of Waitlist and post-transplant outcomes for children with myocarditis listed for heart transplantation over 3 decades by Drs. Amdani S, Asante Korang A, Law Y et al.
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Waitlist and Post-Heart Transplant Outcomes for Fontan patients? Largest analysis of Fontan patients - over 1300 patients! Risk factors for mortality? VAD outcomes? Check out our @PHTSociety. Thank you @JCardFail @CleClinicHVTI @FontanOutcomes
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Learning from #Pediatriccardiology experts @TEDTalks style -“Innovations in Pediatric Cardiovascular Science” come over at 4pm CST @AHAScience @angie_lorts @ACTION4HF #BruceGelb #JackieKreutzer #KeilaLopez #ArashSalavitabar #AHA25 @CleClinicHVTI
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🎉The ACTION VAD Registry has surpassed 2,000 patients enrolled! A huge thank-you to the centers and teams contributing data and driving progress in pediatric VAD care. Your collaboration is making a real difference for kids and families. #PedsVAD #PedsHF #Collaboration
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Congrats to Dr. Madeleine Townsend from @ClevelandClinic! Her ACTION abstract was accepted as a moderated poster at the AHA Scientific Sessions this week! Learn more: https://t.co/R7Tmbbq2xt
#AHA25 #PedsVAD #Collaboration
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Want to learn tips and tricks for writing an @AHAScience Statement? See you all on 11/7 bright and early at 8 am - New Orleans Theater A #AHA25 @CleClinicHVTI
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Thank you to @PHTSociety and the amazing investigators. Also thanks to @JACCJournals for publishing !
Throwback Thursday: @PHTSociety analysis of Prevalence and Impact of Recurrent Rejection on Pediatric Heart Transplant Recipients: A PHTS Multi-Institutional Analysis by Drs. Amdani S, Kirklin JK, Cantor R, et al.
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Thriving Beyond Survival: Confronting the Cardio-Kidney-Metabolic Threat to Long-Term Heart Transplant Outcomes https://t.co/350jYl8Iqv 🙏 to @JACCJournals for inviting me and @NutritionHF for an editorial to the⭐️ work: https://t.co/Kj96Zz6Mgk
@BiykemB @CleClinicHVTI
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After Lisa listened to her daughter’s donor heart beating strongly inside 8-year-old Mireya’s chest, Mireya felt like she needed to give Lisa a hug. It was a long embrace that solidified an unbreakable bond. #DonateLife Mireya’s heart transplant story: https://t.co/H0IikRMxFQ
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Rethinking Heart Failure Therapy in the Fontan Circulation : https://t.co/346WGIGnIR Thank you @JCF @robmentz @dranulala for highlighting this work : https://t.co/Wy5v3Pu0i0
@CleClinicHVTI @CleClinicNews @AlsaiedTarek
onlinejcf.com
Fontan palliation has prolonged survival for patients with univentricular heart defects, yet heart failure (HF) remains a leading cause of morbidity and mortality in this population.1,2 Unlike...
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