SerpellLab
@SerpellLab
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Research groupworking on molecular basis of Neurodegeneration and Alzheimer's disease. Dementia research group. Supported by Alzheimer's society and ARUK
Joined May 2016
We were really excited to write this short article for @alzheimerssoc about AlphaFold2. Lovely work @KarenEMarshall
alzheimers.org.uk
Artificial intelligence technology could be a game-changer for people affected by dementia. Find out why Alzheimer’s Society is supporting research in this area.
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RT @ChurchillHannah: Thank you to @SerpellLab for their @alzheimerssociety guest blog discussing what the Alphafold artificial intelligence….
alzheimers.org.uk
Artificial intelligence technology could be a game-changer for people affected by dementia. Find out why Alzheimer’s Society is supporting research in this area.
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Generate videos in just a few seconds. Try Grok Imagine, free for a limited time.
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RT @TauRx: #Tau is a protein associated with many #brain diseases, including #Alzheimer's. @TauRx believe #education is essential in spread….
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Delighted with this newly submitted paper!.
Read our new work from @SerpellLab using PHF-core Tau fragment, showing that oxidative stress conditions that induce dityrosine crosslinking lead to the trapping of Tau intermediates, preventing them from transforming into fibrils.
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Sharing our two articles from @alzheimerssoc DTC APOE research and Protein misfolding with @TauRx @SussexUni @SussexNeuro @BrainEnergyLab @OGSteele
healthawareness.co.uk
New research is helping to identify why certain genes show increased likelihood of developing dementia. Alzheimer’s disease (AD) is one of many diseases collectively known as dementia. The majority...
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Lovely paper from generated from a chance meeting at a conference! Well done Guna and @mahmoudbukar
pubmed.ncbi.nlm.nih.gov
An N-terminal hepta-peptide sequence of yeast prion protein Sup35 with the sequence GNNQQNY is widely used as a model system for amyloid fibril formation. In this study, we used a reproducible...
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RT @SerpellLab: Frontiers | MIRRAGGE – Minimum Information Required for Reproducible AGGregation Experiments | Frontiers in Molecular Neuro….
frontiersin.org
Reports on phase separation and amyloid formation for multiple proteins and aggregation-prone peptides are recurrently used to explore the molecular mechanis...
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Frontiers | MIRRAGGE – Minimum Information Required for Reproducible AGGregation Experiments | Frontiers in Molecular Neuroscience
frontiersin.org
Reports on phase separation and amyloid formation for multiple proteins and aggregation-prone peptides are recurrently used to explore the molecular mechanis...
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RT @sylvia_schroed: I’m looking for a Phd student to join my lab at @SussexNeuro @SussexLifeSci in September 2021, to study the modulation….
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RT @FEBS_Letters: 👏Highlighted in our new issue: #AmyloidBeta 1-42 internalisation and toxicity are influenced by conformation and assembly….
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RT @BrainEnergyLab: Read @cathnaledi ‘s latest blog all about our #mrc funded research project investigating blood flow and #Alzheimers ! 🧠.
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We loved working with you!.
This work, during my undergrad @SussexUni in the wonderful @SerpellLab, was what made me pursue a career in research! I contributed a very small amount to this paper but it was a very significant part of my baby science career 🤩 #neuroscience.
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Latest work from Devkee Vadukul with @KarenEMarshall and @mahmoudbukar Plus 2 ug project students!! @neuroblonde and Astrid!. Internalisation and toxicity of amyloid‐β 1‐42 are influenced by its conformation and assembly state.
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RT @alzheimerssoc: We're excited to announce this year's virtual Carols at Christmas concert (Thursday 17 Dec) will include a performance b….
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RT @wfxue_lab: Our latest paper investigating the structural polymorphism of #amyloid fibrils is now published with @SpringerNature in @Com….
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RT @LabStahlberg: PostDoc position in Cryo-EM of Neurodegeneration in our group at the EPFL, Lausanne, Switzerland. We offer excellent work….
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RT @wfxue_lab: Can we distinguish seeding through templated elongation, where the specific conformation encoded by amyloid fibrils is propa….
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RT @neuroluci: We have two open possitions in the lab. A permanent Senior Lab Research Scientist (a mix of a permanent postdoc and lab mana….
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RT @RocqueSamantha: Crazy to think I can call myself an author! It's finally out . Thank you so much to @Eddi34165….
onlinelibrary.wiley.com
The pathological spread of tau in Alzheimer's disease and other tauopathies follows a stereotypical pattern in the brain, proposed to occur via a prion-like trans-synaptic transfer. However, the...
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