SCKao
@SCK64778810
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PDRA University of Oxford Rice Chem PhD
Joined April 2022
We expanded our Bismuth LMCT methodology towards the direct decarboxylative C-N coupling of carboxylic acids with sulfonamides - great work by Elina and Dominik now out in @ChemEurJ
https://t.co/leKTufklTC
chemistry-europe.onlinelibrary.wiley.com
Radical processes involving bismuth hold great potential, but innovative strategies are required to control the reactivity of bismuth intermediates. Herein, we report a direct photochemical decarbo...
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I'm excited to share that my newest paper on radical polarity is out now in @J_A_C_S
https://t.co/d4ZgRcTbDM I'm grateful to all the Radical Rockstars in the @nagiblab for the discussions we've had about polarity - and hope this work sparks many more about this kinetic factor!
pubs.acs.org
The polarity of a radical intermediate profoundly impacts its reactivity and selectivity. To quantify this influence and predict its effects, the electrophilicity/nucleophilicity of >500 radicals has...
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Photodriven Ammonia Synthesis from Manganese Nitrides: Photophysics and Mechanistic Investigations | Journal of the American Chemical Society @BrookhavenLab @Princeton @PrincetonChem @pchirik #Photodriven #Ammonia #Synthesis #MnN #Mechanism #Photophysics
pubs.acs.org
Ammonia synthesis from N,N,O,O-supported manganese(V) nitrides and 9,10-dihydroacridine using proton-coupled electron transfer and visible light irradiation in the absence of precious metal photoca...
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Check out our most recent work in @J_A_C_S. Carboxylated amine-borane serves are boryl radical precursor in radical borylation of styrenes and imines to form novel sp3-organoboron materials directly applicable in Suzuki-Miyaura cross-coupling. https://t.co/GyLAsWKz5i
pubs.acs.org
Alkyl organoborons are powerful materials for the construction of C(sp3)–C(sp2) bonds, predominantly via Suzuki–Miyaura cross-coupling. These species are generally assembled using 2-electron proces...
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Congrats on the amazing defense, Dr. kao!! @SCK64778810 I am so grateful for your amazing contributions to our group and it was a true pleasure to support you in this journey and beyond!! Excited for your next steps @OxfordChemistry!! #PhDone
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Excited to share our latest discovery, now published in the @J_A_C_S ! This study unveils a powerful combination of iron and organocatalysis for achieving enantioselective α-amidation of aldehydes. https://t.co/CzSXr7xhnH
pubs.acs.org
The strategic integration of organocatalysis with transition-metal catalysis to achieve otherwise unattainable stereoselective transformations may serve as a powerful synthetic tool. Herein, we...
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Directed Hydrogen Atom Transfer for Selective Reactions of Polyenols | Journal of the American Chemical Society @TotalSyntheses @UCIrvine #HAT #Polyenols
pubs.acs.org
Directed hydrogen atom transfer to alkenes is described. The process is catalyzed by iron complexes and allows for the site-selective hydrofunctionalization of polyenols. Experimental data suggest...
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Enantioselective Synthesis of Allylic Sulfones via Rhodium-Catalyzed Direct Hydrosulfonylation of Allenes & Alkynes | Journal of the American Chemical Society @AponickGroup @UF #Enantioselective #Allylic #Sulfones #Rh #Hydrosulfonylation #Allenes #Alkynes
pubs.acs.org
A highly regio- and enantioselective hydrosulfonylation using commercially available sodium sulfinates is reported, providing the first direct asymmetric rhodium-catalyzed hydrosulfonylation of...
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Fe/Thiol Cooperative HAT Olefin Hydrogenation: Mechanistic Insights That Inform Enantioselective Catalysis | JACS @pushingarrows @RiceUniversity @Yale @YaleChem #FeThiol #HAT #Olefin #Hydrogenation #Enantioselective #Catalysis #Cooperative #Mechansim
pubs.acs.org
Asymmetric hydrogenation of activated olefins using transition metal catalysis is a powerful tool for the synthesis of complex molecules, but traditional metal catalysts have difficulty with enanti...
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Excited to share the first application of Stack ligand in Rh-catalyzed reaction. The direct asymmetric hydrosulfonylation with allenes/alkynes has been an unsolved mystery for 10 years, and (Rax,S,S)-StackPhim is the answer for it! @AponickGroup @J_A_C_S
https://t.co/mYLr4taUff
pubs.acs.org
A highly regio- and enantioselective hydrosulfonylation using commercially available sodium sulfinates is reported, providing the first direct asymmetric rhodium-catalyzed hydrosulfonylation of...
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Fe/Thiol Cooperative Hydrogen Atom Transfer Olefin Hydrogenation: Mechanistic Insights That Inform Enantioselective Catalysis @J_A_C_S #Chemistry #Chemed #Science #TechnologyNews #news #technology #AcademicTwitter #ResearchPapers
https://t.co/aHQmkUN7aW
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Enantioselective Synthesis of Allylic Sulfones via Rhodium-Catalyzed Direct Hydrosulfonylation of Allenes and Alkynes @J_A_C_S #Chemistry #Chemed #Science #TechnologyNews #news #technology #AcademicTwitter #ResearchPapers
https://t.co/VVvuyWkkbr
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Mechanism of Ni-Catalyzed Photochemical Halogen Atom-Mediated C(sp3)–H Arylation | Journal of the American Chemical Society @UCLA @uclachem #Mechanism #Ni #Photochemical #Arylation #CHFunctionalization #Halogen @TotalSyntheses
pubs.acs.org
Within the context of Ni photoredox catalysis, halogen atom photoelimination from Ni has emerged as a fruitful strategy for enabling hydrogen atom transfer (HAT)-mediated C(sp3)–H functionalization....
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Asymmetric photoredox catalytic formal de Mayo reaction enabled by sensitization-initiated electron transfer
nature.com
Nature Chemistry - The redox properties of visible-light-absorbing photosensitizers are limited by the energy of visible photons, but methods using sensitization-initiated electron transfer have...
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Now online: Article by Yunfang Yang, @MarcGBQ, @xiongyih & co-authors Engineering non-haem iron enzymes for enantioselective C(sp3)–F bond formation via radical fluorine transfer https://t.co/0HRt81IJFI ($)
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Synthesis of Collidine from Dinitrogen via a Tungsten Nitride @J_A_C_S #Chemistry #Chemed #Science #TechnologyNews #news #technology #AcademicTwitter #AcademicChatter
https://t.co/EkM4SY0uho
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!! Our group's first publication is now available in the J. Am. Chem. Soc.! We developed a scalable, iron-catalyzed cross-electrophile coupling and used it in a number of applications! We sincerely thank reviewers for strengthening our report. Please join me in congratulating
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A call for sustainable chemistry! Discover water to make photoreactions with commercial Fe(II)/Fe(III) salts by adding ligands that favour LMCT transitions! An inspiring rewiew from Jessica! @green_rsc
https://t.co/LwcvhroUUH
pubs.rsc.org
Iron, mostly as Fe2+ or Fe3+ bound in oxides, is the second most common element in the Earth's crust after aluminium. Salts of the d-block metal are cheap and commercially available and have already...
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Our efforts to unlock the potential of Sulfinyl-Smiles for asymmetric alkene difunctionalizations now out in @NatureChemistry. Big👏to this incredible, tireless team for making it happen💪! #Asymmetry❤️Alkenes @UZH_Chemistry @UZH_Science
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