
Rob Wiesheu
@RobWiesheu
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Postdoc at Dana-Farber Cancer Institute / Harvard Medical School, PhD @CRUK_SI @CoffeltLab. Interested in all things cancer immunotherapy. First gen
Boston, MA
Joined May 2019
Happy to see this commentary about most recent updates in the gamma delta world from @CoffeltLab and myself out. Happy reading.
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Bittersweet leaving Scotland, Glasgow, @CRUK_SI and @CoffeltLab today. Very grateful for the past 6 years and all the people I’ve met. Also very excited to move over the pond. Buckle up Boston, here I come 🇺🇸
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Excited to share our new publication in @EurJImmunol. We have shown that IL-17A-producing Vγ4 γδ T cells are regulated by PD-1 in the EAE model. Thanks to @MillsKingston for the support and supervision as well as Caroline Sutton and Barry Moran @tcdflow
https://t.co/Orm65rpe60
onlinelibrary.wiley.com
PD-1 signaling suppresses IL-17A production by TCR-activated CD27− Vγ4 γδ T cells. Anti-PD-1 treatment exacerbates experimental autoimmune encephalomyelitis by enhancing IL-17A production by CD27−...
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A more detailed overview of our most previous findings on our favourite immune cells. Many thanks for everyone involved!!!
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From our lab to your journal club. Over the moon to see the bulk of my PhD out in the wild. Massive thanks to @sarah_cedwards, @CoffeltLab and everyone involved.
IL-27 maintains cytotoxic Ly6C+ γδ T cells that arise from immature precursors https://t.co/NkRbZkgXHW
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Thrilled to share our new findings in @NatImmunol on perinatal thymic-derived #CD8ab-expressing #gammadelta T cells that play a role in health and disease. Team work makes the dream work with @DanPennington1 @GJ_Fiala & @BSilva_Santos @blizard_inst @QMUL
https://t.co/Pr8iOGiEiK
nature.com
Nature Immunology - Here the authors identify and characterize the development and function of an IFN-γ-producing CD8αβ+ subset of γδ T cells that contributes to malignancy.
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Agree @AmyShergold, was a fab night with great engagement and discussions, but think gdTcells are still best immune cell. Glad we agree on the coasters though.
Had a great time at @pintofscience with @RobWiesheu and @XimenaRaffo talking about cancer immunology 🍻 I hope I managed to convince everyone that dendritic cells are the coolest of all the immune cells 😉 How cool are audience’s immune-themed coaster designs? 🦠
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With @CoffeltLab, we had fun writing a little perspective for @ImmunityCP on the latest cool work by the @megeblad lab about neutrophils, stress, and metastasis! Neutrophils rock... but can be scary when stressed! 😅 https://t.co/47TjrQQLQv
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Come along to Dow’s bar on the 14th May to hear @XimenaRaffo, @RobWiesheu and I talk all things immune cells in cancer! https://t.co/7Mebc6eTph
pintofscience.co.uk
Our bodies truly are amazing but when things go wrong, we can be left with terrible illnesses, and we all know someone who has suffered from the Big C canc…
✨Tickets for #pint24 are now on sale!✨ 🎟Book here 👉 https://t.co/tA4R5NQ4R9 👈 🐝🧪👩🔬📚🔬👓🧠🐟🫀💫🥼👨🔬🔭🧫🦴 🗓13th-15th May 2024 📍40+ locations across the UK 🗣450+ events
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Beyond thrilled to have ticked this box. Many thanks to @CoffeltLab for all the support and many others along the way. Enjoyed the ride.
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My first first author research paper is finally out! 🤩 Read about how NKG2D can promote cancer progression by modulating IL-17A-producing γδT cells here, in the first issue of @discovimmunol
academic.oup.com
Abstract. γδT cells are unconventional T cells particularly abundant in mucosal tissues that play an important role in tissue surveillance, homeostasis, an
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For everyone liking their T cells unconventional. And everyone else, too.
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Andy & @CRUK_BI are walking in memory of Elaine to raise funds for @BreastCancerNow #WearItPink @CoffeltLab @barbaraalaing @JackieBeesley2 @RobWiesheu
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Single-cell analysis uncovers differential regulation of lung γδ T cell subsets by the co-inhibitory molecules, PD-1 and TIM-3 https://t.co/gYUdd72qMI
#bioRxiv
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Awesome new overview of immunotherapy for metastasis by the pals @sarah_cedwards @WilmaHM2 out today. Check it out.
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Meet researchers from @CRUK_BI in Scotland. Medical research charities provide salary funding for over 17,000 researchers across the UK. Ambitions to improve outcomes for #cancer patients cannot be met without investment. @RishiSunak @HMTreasury will you protect #ResearchAtRisk?
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Great opportunity to discuss how lockdown has impacted my research, and also to raise the profile of the @PancreaticCanUK Future Leaders Academy at @CRUK_BI 💜 @CoffeltLab
A PhD student researching pancreatic cancer, Mark talks about how lockdown has impacted his approach to work
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