I am excited to announce several post-doc positions studying gene regulation and cell biology of spirochetes are available in the @NIH Biology of Spirochetes Unit, opening 2025 in Bethesda, MD @NIAIDNews! Join our team and work on the dynamic NIH campus:

Another great Microbial Stress Response GRC! Another fun get together with current and former lab members!

Ptype ATPases 😆

We were kindly asked by #CellCalcium to write a perspective on a paper in @MolecularCell claiming that the TMEM94 protein is a Mg2+transporting P-type ATPase of the ER membrane. Turned into piece with a lot caution - many basic experiments are missing 😬 https://t.co/6j1QuRjDEy

We are looking for a talented postdoc to join us by 8/24 to continue our efforts towards understanding the mechanism of Mg2+-transport & oligomerization of P-type ATPases using molecular biology, biochemistry, structural biology (#cryoem) and MD. Please DM me if interested.

Taking postdoc applications till the end of March. One week left to submit. Please RT!

Congrats @amycamp and her team of amazing undergrads! I look forward to reading.

Finally, we are looking forward to many future structural insights into MgtA/B in their native lipid environments and their regulation by small proteins.

Intriguingly, the extensive dimer interface would not be disrupted by mutagenesis and retain its fold. Additionally, we provide structural insights into ATP binding and transport of mg across the membrane.

To our surprise MgtA was a dimer, the first recorded for this family. Additional work with gentle membrane extractions is warranted for other members of this family!

So what did we find? First, the closest mammalian relative of MgtA is the extensively studied SERCA Ca transporter which is thought to be a monomer by structural work including cryo and x-ray.

Thankful to have had the opportunity to learn various mass spectrometry approaches at the @MpiBrain with Julian Langer’s lab.

I’m excited to share my first postdoctoral work where we captured the first high resolution structure of the bacterial magnesium transporter MgtA! This project allowed me to learn cryo with @DoreenMatthies, molecular simulations with @AlexSodt and function with @storzlab.

We discovered a new B. burgdorferi flagellar assembly factor that is broadly conserved across the bacterial superkingdom! Work by two @NICHD_NIH postbacs: @MaximeZamba & Daniel Soliman, with @storzlab JewettLab @jivarahasya @JunLiuLab P.S. There is no Hfq https://t.co/saM4yNTKni

Interested in RNA, spirochetes and ticks? Consider applying for a fully-funded post-doctoral position in my lab @NIH main campus! For inquires email a CV and the names of three references. #postdocposition #RNA Please share!

Can’t wait to see the amazing things tiara will do during her graduate studies!

Having a little fun in lab is never a bad thing!

Science is hard. Good research makes you feel stupid. You're inadequate for the task at hand. How else would it be? You're pushing the boundaries of knowledge. Get used to it. This process is immensely rewarding.

Such a heavy loss for our NIH community. Christina was incredibly brilliant and will be deeply missed. I admired her not only as a scientist but as an advocate for trainees. Rest in peace friend.

I can’t get enough of this rain coat 🤣… he actually loves it