ReichertLab
@ReichertLab
Followers
2K
Following
569
Media
15
Statuses
413
Mitochondrial research, Heinrich Heine University Düsseldorf, Germany
Düsseldorf, Germany
Joined June 2019
A long journey which started more than 10 years ago and finally is out. Great team work with the Escobar-Henriques Lab.
Online Now: Ubiquitin precursor with C-terminal extension promotes proteostasis and longevity https://t.co/GkHutY4Qaa
0
4
8
Have a look at our joint study with the #Philipp Lang Lab @HHU_de @MedHHU @KondadiLab revealing how cristae morphology affects viral replication, immune metabolism and immunity. Thanks to all collaborators.
cell.com
Katahira et al. show scRNA-seq indicating roles of mitochondrial membrane architecture during VSV infection. Altered mitochondrial structure-metabolism by F1FO ATP synthase inhibition, inducing...
1
7
28
Have a look at our joint study with the #Philipp Lang Lab @HHU_de @MedHHU @KondadiLab revealing how cristae morphology affects viral replication, immune metabolism and immunity. Thanks to all collaborators.
cell.com
Katahira et al. show scRNA-seq indicating roles of mitochondrial membrane architecture during VSV infection. Altered mitochondrial structure-metabolism by F1FO ATP synthase inhibition, inducing...
1
7
28
Noga Preminger @Noga_Preminger, Ben Zucker, Sarah Hassdenteufel, Michael Kozlov, Maya Schuldiner & colleagues identify mitochondrial inner membrane remodelling as a driving force of organelle shaping using their data-driven biophysical model. https://t.co/wtJwqtWape
#OpenAccess
2
4
12
Also honored to see our work highlighted in @Nature! Huge thanks to Navdeep S. Chandel and Ram P. Chakrabarty for the fantastic News & Views piece, describing the unexpected role of Ogdh and alpha-ketoglutarate in intestinal healing https://t.co/UJM6ydFjdf
nature.com
Nature - A key component of the TCA cycle, a series of reactions that occurs in energy-generating organelles called mitochondria, can dictate the fate of intestinal stem cells.
4
25
167
Thrilled to share our newest publication in Materials & Design https://t.co/MehZfLeWMx: combinational treatment of the antimalarial drug chloroquine and nanoceria selectively kills triple negative breast cancer (TNBC) cells in a 2D and 3D cell system. To all authors: well done
1
3
5
What is the fate of mitochondria shed in migrasomes? While disposal of dysfunctional mito promote cellular health, the process is responsible for DAMPs eg. N-formyl peptides & cardiolipin, that trigger innate immune responses. #Aging 👨🏼🦳#inflammation 🔥
cell.com
Mechanisms by which cells remove damaged mitochondria extracellularly are unclear. Recent work by Jiao and colleagues in Cell shows that migrating cells expel dysfunctional mitochondria in membrane...
0
28
87
What complex are you if you have the most versatile company in close proximity? The MICOS Complex. Presenting the MINDNet: Proximity Proteomics @ReichertLab @HHU_de @UniklinikDUS. The work was done by talented Yulia Schaumkessel.
MINDNet: Proximity interactome of the MICOS complex revealing a multifaceted network orchestrating mitochondrial biogenesis https://t.co/91IIbgKA9C
#biorxiv_cellbio
0
7
20
Preconditioning of human iPSCs with doxorubicin causes genome-wide transcriptional reprogramming in iPSC-derived cardiomyocytes ... https://t.co/9YPoNJLd45
#biorxiv_cellbio
biorxiv.org
Background The anthracycline doxorubicin (Dox) is a widely used genotoxic chemotherapeutic drug with known dose-limiting cardiotoxic effects. How Dox-induced damage either to cardiomyocytes or to...
0
1
5
We show that preconditioning of iPSCs with low pulse- treatment with a chemotherapeutic drug, doxorubicin, alters the fate of cardiomyocytes that originated from such treated cells. They become transcriptionally reprogrammed in a way that impaires cardiac muscle regeneration.
Preconditioning of human iPSCs with doxorubicin causes genome-wide transcriptional reprogramming in iPSC-derived cardiomyocytes ... https://t.co/9YPoNJLd45
#biorxiv_cellbio
0
3
11
Excited to share our latest paper in @ScienceAdvances! We finally dissected a new pathway for mitochondrial quality control upon mtDNA replication stress! Let’s start a short thread! 🧵 https://t.co/YPb6TMTitu
science.org
Lysosomal uptake of mtDNA controls mitochondrial quality.
5
31
104
Are u tired of reading about tariffs? Then take a look to our last work! @ScienceAdvances
https://t.co/YPb6TMTitu
science.org
Lysosomal uptake of mtDNA controls mitochondrial quality.
0
6
26
Congrats! Very important study.
Are u tired of reading about tariffs? Then take a look to our last work! @ScienceAdvances
https://t.co/YPb6TMTitu
0
0
1
There is still the chance to register for the webinar with Nils Wiedemann, Agnieszka Chacinska, Toni Barrientos, Jan Riemer and myself next Tuesday! 250 mitochondria lovers already signed up! @Riemerlab @A_Chacinska @Antonio41949078 @Mito_News
⌛️Hurry up and register to our free webinar ❓Find out more about the beating heart of the eukaryotic cell! 📅 Tuesday Nov 19 🕒15:00 GMT / 16:00 CET 👉Register here: https://t.co/n3WdZdJ0z4
#PhDChat #PhDForum #ECRchat #PostDocChat #PostDoc #PostGrad
@FEBSnews
1
9
22
The newly founded study group on Cellular Organelles of the German Society for Biochemistry and Molecular Biology @GBM_eV had its first symposium in Kaiserslautern. Exciting meeting with excellent talks and posters! So much fun! Next year, we organelle lovers meet in Düsseldorf!
3
6
65
Still time to register and join for this exciting meeting in Düsseldorf, Germany, on “Climate change: consequences and possible solutions“ organized by the #BMFZ @WeberLab_HHU @HHU_de @MedHHU #Klimaschutz
https://t.co/0z26ljlaE9
0
4
3
For all the metabolism lovers, we are excited to demonstrate that mitochondrial apolipoprotein MIC26 is a metabolic rheostat regulating central cellular fuel pathways! @melissalubeck10 @WeberLab_HHU @ReichertLab @ruchikancbs @UniklinikDUS @HHU_de
life-science-alliance.org
Mitochondria play central roles in metabolism and metabolic disorders such as type 2 diabetes. MIC26, a mitochondrial contact site and cristae organising system complex subunit, was linked to...
2
7
22
Accumulating evidence indicates that #mitochondria are not only the powerhouses driving the heart’s function, but also play a critical role in regulating mammalian embryonic heart development through non-energetic #metabolic processes. https://t.co/8axjKinUZ5
3
61
213