Andrew Steele
@ReeleSteele
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Post-doc in the Shen lab at Scripps Florida. Former @wuestlab member. Interested in natural product total/biosynthesis!
Jupiter, FL
Joined January 2017
Tap/process water can also act very different as antisolvent in crystallizations compared to miliQ.
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Check out our characterization of a novel PKS domain responsible for persulfide formation! https://t.co/8DjDDLAvU1 congrats to authors Song, @ReeleSteele, Wei, @Kalkreuter, and the past members who helped make this happen!
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Hot off the press! We characterized a persulfide intermediate in the biosynthesis of a family of natural products that has puzzled the Shen lab and the community for decades.
nature.com
Nature Communications - Enzymes installing an intact hydropersulfide (-SSH) group into natural products have so far not been identified. Here, the authors report the characterization of an...
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A look at a 1/4 of the strains we harvested this week for the NPDC @lab_shen @scrippsresearch #bacteria #microbiology #genomesequencing
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Check out our latest collaboration with our neighbors in Renata lab @hanzyduzit. Great job to all invovled! 🧫🧪
By hijacking enzymes from bacterial strains in Scripps Research’s Natural Products Discovery Center, Profs. Hans Renata & Ben Shen have been able to make complex, medicinal molecules that are usually only obtainable from plants https://t.co/NKeMUdWbEH
@ScienceMagazine @hanzyduzit
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We are currently looking for postdoc(s) to join our lab with experience in bioinformatics, genome mining, and development of technologies for BGC activation in native and heterologous hosts for NP discovery. See full listing here ( https://t.co/af8kkuED3L)
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We are currently looking for a motivated postdoc to lead our lab's structural biology initiative. Experience with natural product biosynthesis is preferred. Exceptional candidates with extensive independent research experience may be appointed to the rank of staff scientist.
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Really exciting work from @Dawson_Group and @BaranLabReads and my former labmate @KyleKnouse - custom DNA probes in a matter of 2 days and less $ than a steak dinner.
In this latest addition of collaborative work with @baranlabreads, we present SENDR with this shared tweet thread! https://t.co/e2IrE4aFBE
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So honored to have gotten this great news yesterday!
Congrats to fellow postdoc Andrew (@ReeleSteele)for receiving the Division of Medicinal Chemistry 2020 Scarborough Postdoctoral Award! @scrippsresearch
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Behind the scenes part 4: extracts & fractions. We recently dissolved and transferred >30,000 samples from 1,388 24-well plates to 347 96-well plates (soon to also be in 384 format) for future metabolics and HTS 🎉 #naturalproducts #NPDC @scrippsresearch #drugdiscovery
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This is the best time in history to be studying #naturalproducts and the best place to study them @lab_shen!
wpbf.com
Walking into a cold shed on the Scripps Research Jupiter campus is like walking back in time.
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new enediyne BGC and enediyne-related compounds from a strain of Micromonospora 👀 @lab_shen @cnteijaro
https://t.co/jg7pAz15nl
pubs.acs.org
We report the genome-guided discovery of sungeidines, a class of microbial secondary metabolites with unique structural features. Despite evolutionary relationships with dynemicin-type enediynes, the...
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Time to help these little bacteria make a huge difference! #naturalproducts
New decade, new naturals products!🎉 #naturalproducts #drugdiscovery #straincollection
https://t.co/9JUaD47id2
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I was talking about grad school last night and accidentally called @wmwuest "dad" instead of "bill".... 😳
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Today we shed blood, sweat, and paint together!
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Congrats @cnteijaro! I know the team has been di-yne to get this published!
Checkout our latest work in enediyne biosynthesis @JOC_OL
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No sleep till.... Publication! #WuestieBoys
Congrats to @ReeleSteele, Erika, and Maddie on their latest paper with our collaborators at @BrownUniversity and @harvardmed! We show that ntzdpa (a PPAR agonist) is also an effective antibiotic against persistent MRSA ( https://t.co/Cqx6iEoKTV)!
@EmoryChem @CFAtlanta
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"Bad science" pre-prints and open access articles can cause unnecessary panic! @cnteijaro he mentions the evil GMO article we presented the other day 😵 https://t.co/4mlvi9C7Pj)
nature.com
Nature - The scientific community must take measures to keep preprints from distorting the public’s understanding of science, says Tom Sheldon.
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