Robert Gilchrist
@RG_EggLab
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Prof and NHMRC Fellow at UNSW, Sydney; Head Oocyte Biology Research Unit; Director of Research, SWCH; oocyte and reproductive biologist
Sydney, New South Wales
Joined August 2016
Thanks Claire. Lots of ups and downs along the way but it has been worth it
Wow! I remember when this was your dream Rob People don’t have a clue about how hard it is to get our great science from bench to bedside Congratulations!🙌
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Grateful for this lovely writeup of our work on chemo induced infertility in @EmboMolMed! Many thanks to @norahspears @AgnesStefansd and Adomas Liugaila Can we manipulate the ovary’s own metabolism to protect it from chemotherapy-induced damage?
embopress.org
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Hormone-free infertility treatment....well, here we are finally...it's a clinical reality!! 20 years ago, our old IVM alliance: myself, @jeremygthompso2, Johan Smitz and @MdevosMD made this our aspirational goal. Now Dr Lan Vuong and @TuongMHo got there!!
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Super article that one…ha ha 😁😁
New #openaccess review published as part of the Reproductive Ageing collection: 'Reproductive Ageing: Metabolic contribution to age-related chromosome missegregation in mammalian oocytes' by Bettina P Mihalas et al. Read it here: https://t.co/HCsHcg7Giv
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Some few more pictures that need to de shared #Ssr2024 @SSRepro
@AlbertoMLuciano @RG_EggLab #Johan_Smitz @ufpjhansen @Federic37835007 @GiuliaMusmeci55 @MarcSirard @masroorsagheer2
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What an achievement from @TuongMHo and the @research_hope , completely hormone-free ART with good pregnancy outcomes. Only possible with an advanced IVM system. Awesome - we have been waiting a long time to get to this point. Congrats!!
Hormone-free ART for PCOS women | Presented at ESHRE 2024 to a large audience. It is feasible and efficient. Single blastocyst transfer with good pregnancy outcome.
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Interested in IVM in hyperresponders? 👉 Check our poster on (cori)follitropin priming of antral follicles and the impact on oocyte yield and pregnancy rates #ESHRE2024 @BrusselsIVF @UZBrussel @ESHRE
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fantastic work @TuongMHo @research_hope . OTO-IVM (ex vivo IVM; immature oocytes from ovarian tissue) is a no-brainer for fertility preservation for a lab routinely running IVM for infertility treatment. Easy peasy !!
OTO & CAPA IVM | We retrieved immature oocytes from ovarian tissue, applied biphasic IVM. We got 22 MII oocytes for vitrification in this case. Really potential !
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Ask the Experts - what is IVM? https://t.co/z34KmqTw1N via @YouTube
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This is what mastery of IVM looks like #ESHREjc and with zero patient stimulation!
Another day of IVM in December last year and results. All four were PCO women, without stimulation before OPU.
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Wow..!! Zero stimulation ART is a thing! This is what can be achieved when you have an excellent quality and very experienced IVM clinic. Congrats @TuongMHo and @research_hope
Why stimulation for PCO women? Today we have 4 cases of IVM for PCO. We collected at least 20 oocytes each, without any gonadotropin priming. Our maturation rate is > 60%. > 90% of our IVM cases have blastocysts for transfers.
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@SofiaMakieva @OmarRawi89 @VuongThiNgocLan @krammecc Good question … An inverse relationship between the oocyte developmental status at collection and the length of pre-IVM culture has been hypothesized (Gilchrist et al. 2024) @RG_EggLab. Oocyte developmental status depends on gonadotropin (dose) priming, follicle size. #ESHREjc
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@FlorSR5 @RG_EggLab @SofiaMakieva @krammecc @GLiperis @BortolettoMD @MdevosMD @VuongThiNgocLan @maclaudiaa @juanjo_fraire At least 10% IVF patients should not have ovarian stimulation, to get enough embryos for high accumulative live birth rate per OPU.
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@SofiaMakieva @krammecc @GLiperis @BortolettoMD @RG_EggLab @MdevosMD @VuongThiNgocLan @maclaudiaa @juanjo_fraire I do not believe we should see IVM as replacing IVF. However IVM should be acknowledge for their advantages and should be considered as a complementary tool available for the treatment of a selected groups of patients (hyperresponders) within a conventional IVF program. #ESHREjc
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🛎️Its #ESHREjc o’clock 🛎️ Follow @ESHRE for the discussion threads (aka Questions)! Topic: IVM🥚 Paper: https://t.co/m9ekgHScjY Invited panel: @MdevosMD @FlorSR5 @krammecc @BortolettoMD @VuongThiNgocLan @RG_EggLab Moderators: @maclaudiaa @OmarRawi89 @GLiperis @juanjo_fraire
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@juanjo_fraire
https://t.co/HOZiIZqVwO Good to read about the new IVM system. We have good results with this. More than 800 babies have been born. Three-year follow up of children has been assuring. #ESHREjc
academic.oup.com
AbstractBACKGROUND. While oocyte IVM is practiced sporadically it has not achieved widespread clinical practice globally. However, recently there have been
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For #ESHREjc we feature an excellent paper on IVM 🧫 (tweetorial below) and discuss with @MdevosMD @FlorSR5 @krammecc @BortolettoMD @VuongThiNgocLan and @RG_EggLab! Join us at 5pm CET tomorrow at @ESHRE 🤗 @maclaudiaa @OmarRawi89 @GLiperis @juanjo_fraire @SofiaMakieva
🪩 IVM in all its glory 🪩 The study of Mostinckx et al ( https://t.co/NV42uUeNov) addressed 🧫 In Vitro Maturation (IVM) vs 💉Ovarian Stimulation (OS) for women with high AMH👸🏻 (aka ~PCO aka hyper-responders) Here a 🧵 summary in preparation for #ESHREjc this Friday👇🏻
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Looking forward to joining the expert panel for this #ESHREjc on this afternoon/evening to discuss all aspects of IVM
🪩 IVM in all its glory 🪩 The study of Mostinckx et al ( https://t.co/NV42uUeNov) addressed 🧫 In Vitro Maturation (IVM) vs 💉Ovarian Stimulation (OS) for women with high AMH👸🏻 (aka ~PCO aka hyper-responders) Here a 🧵 summary in preparation for #ESHREjc this Friday👇🏻
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Our new article - Update on IVM. It is a potential alternative in modern ART.
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