Michele Ardolino
@QFKC
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Tumor immunologist, President of CSKA Tuscano and evolutionary successful
Ottawa, Ontario
Joined January 2013
Shout out to twitter less rockstars Kathy McCoy, Seb Talbot and Nicolas Jacquelot!!!
🩺 Why do immunotherapies—treatments that mobilize the body’s own immune system to fight cancer—succeed for some patients but fail for others? A bold new research collaboration led by Dr. Michele Ardolino at the University of Ottawa Faculty of Medicine aims to uncover the hidden
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Congratulations to the 7 recipients of the CRS’ 2025 Next Generation of Scientists Awards! They represent the future of cancer research in Canada. 🔬 Learn more: https://t.co/BNxYfSDtiu
#Cancer #Research #NextGenerationOfScientistsAwards
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True, but @CIHR_IRSC please say yes when we ask you to go back to in person panels
🔬💰 Shape the future of research! CIHR needs peer reviewers to evaluate Fall 2025 Project Grant applications. Say “YES” when asked to #PeerReview! https://t.co/1AXYMzxCEZ
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From the lab to the pages of Science! 🧬 Congratulations to Dr. Baenziger on the publication of “Asynchronous subunit transitions prime acetylcholine receptor activation.” https://t.co/q5sfNKjeOR
#CIHR #NSERC
science.org
Communication at synapses is facilitated by postsynaptic receptors, which convert a chemical signal into an electrical response. For ligand-gated ion channels, agonist binding triggers rapid transi...
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In a #TopRead from August, @LabWaggoner from @CincyResearch discovered that the transcription factor ASCL2 is required for recruitment of NK cells into the spleen and white pulp providing novel insights into NK cell biology. Read more: https://t.co/UtnkVTkJAw
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The best conferences are always the small, intimate, focused ones where ideas fly freely. This one is a premier example!!! Looking forward to seeing everyone there and brainstorming on the hottest topic in immunology!
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Congratulations to Dr. Alarcón for being named one of Canada’s most inspiring immigrants! Born in Chile, he now leads groundbreaking research at the @HeartInstitute, contributing to foster more accessible environments for researchers with disabilities:
📣 Congratulations to our researcher Emilio Alarcón, PhD (@EmilioIAlarcon1), for being named one of the Top 25 Canadian Immigrants of 2025! 👏 Read more 🔽 https://t.co/szD3ioSta7
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wondering what ILCs do in cancer? so do we! take a peak at this minireview Sara and Megan wrote https://t.co/wRqOSoXy6h
@uOttawaMed @uOttawaBMI @OttawaHospital
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Intra-Tumoral Treg Ablation Unleashes NK Cell-Mediated Control of CD8 T Cell-Resistant Tumors https://t.co/zJlEZMLAqq
#biorxiv_immuno
biorxiv.org
Cancer cells frequently lose MHC I to evade CD8+ T cell recognition. While Natural Killer (NK) cells are poised to target MHC I-deficient cancer cells, MHC I loss alone is often insufficient to...
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Hodgins et al. of the Ardolino Lab show that PD-L1 promotes oncolytic virus infection via a metabolic shift that inhibits the type I IFN pathway. https://t.co/njSLu8BkDn 📘 In our #Immunometabolism 2025 collection: https://t.co/PmqGpK64oP
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Refined cell transfer model reveals roles for Ascl2 and Cxcr3 in splenic localization of mouse NK cells during virus infection https://t.co/YOVS7oMyKu
#biorxiv_immuno
biorxiv.org
Cell transfer experiments complement the rigorous investigation of antiviral and antitumor functions of natural killer (NK) cells. Success in these endeavors is enhanced by expansion of small numbers...
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~<3
Online Now: The Terry Fox Research Institute Marathon of Hope Cancer Centres Network: A pan-Canadian precision oncology initiative https://t.co/9vjT8wQWlv
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True, but also important trying to reintroduce in person panels.
Shape the future of research! 🔬💰 CIHR needs peer reviewers to evaluate the Spring 2025 Project Grant applications. Say “YES” when asked to #PeerReview
https://t.co/8WS1jP9W99
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Jonathan’s paper was highlighted in the tumor #metabolism collection :)
.@darwinsbro, @QFKC et al. @ArdolinoLab show that PD-L1 promotes oncolytic virus infection via a metabolic shift that inhibits the type I IFN pathway. https://t.co/HrqjfbSjeJ 📘 In Tumor #Metabolism 2025: https://t.co/xND9s10p4g
#KSTumorMetab25
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Immune-molecular interactions in high-grade serous ovarian cancer distinguish long-term survivors: https://t.co/HL7FsSli3I
@JeanetteEB @DalhousieU comments on Nelson et al. ( https://t.co/xr8hIR3qA1)
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Don’t miss out! A Conversation About Creating Tomorrow episode 2 with Dr. Rebecca Auer shares how the new hospital campus is bringing cutting-edge research to the bedside. Watch now: https://t.co/4GXHR4sWP7
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🎓✨ Curious about graduate studies @uOttawaMed? Join us for our #OpenHouse! 🗓️ November 29, 2024 📍 Roger Guindon Hall 🔗 Register now: https://t.co/BSdIuTf4Ru
#GraduateStudies #uOttawa
uottawa.ca
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