Daniel Kim
@ProfDanielKim
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Assistant Professor @BaskinEng @UCSC | Associate Member @CanaryCenter @Stanford | Research Scholar @AmericanCancer | Chair, Media & Communications @RNASociety
San Francisco Bay Area
Joined April 2016
Super excited to share our latest work on #RNA liquid biopsy via @nanopore sequencing for novel biomarker discovery and #cancer early detection!. Thank you @AmericanCancer @ACS_Research for supporting our research!
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RT @ProfDanielKim: Super excited to share our latest work on #RNA liquid biopsy via @nanopore sequencing for novel biomarker discovery and….
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RT @biorxiv_genomic: RNA liquid biopsy via nanopore sequencing for novel biomarker discovery and cancer early detection .
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This work was spearheaded by two amazing grad students, co-first authors Vikas Peddu & Alex Hill, with significant contributions from Sreelakshmi Velandi Maroli & Connor Mattingly, as well as our wonderful collaborators Joshua Gardner, Karen Miga, and Rebecca Fitzgerald!.
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Our study highlights the utility of our long-read sequencing-based RNA liquid biopsy approach for discovering and targeting early stages of disease with molecular precision.
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Through our LOCATE-seq RNA liquid biopsy platform technology, we also discovered potential therapeutic targets, including metabolic, signaling, and immune checkpoint pathways, that are highly upregulated in both precancer and cancer patients.
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Using these novel, unannotated cell-free RNAs, we built a custom transcriptome reference for quantification, feature selection, and machine learning to accurately classify both precancerous Barrett's esophagus with high-grade dysplasia and early-stage esophageal adenocarcinoma.
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We leveraged the power of single-molecule, long-read sequencing of cell-free RNA using Oxford Nanopore Technologies' PromethION platform to discover over 270,000 novel, intergenic cell-free RNAs.
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RT @nanopore: A new study shows how Oxford Nanopore sequencing of cell-free RNA can distinguish healthy, precancerous, and cancerous states….
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RT @ProfDanielKim: Join us in the fight against cancer! Please consider making a gift today to advance the future of cancer early detection….
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Join us in the fight against cancer! Please consider making a gift today to advance the future of cancer early detection & to support the next generation of cancer researchers! .
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RT @RNASociety: Register today for RNA 2025 - the 30th Annual Meeting of the RNA Society! This year’s meeting will be held at the beautiful….
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RT @RNASociety: We are pleased to announce registration for RNA 2025 - the 30th Annual Meeting of the RNA Society - is now open! . https://….
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RT @SCIDirector: SCI member @cncurtis & others found #BreastCancer spans three genomic archetypes: ER+ high-risk tumors with complex amplif….
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RT @ucscbme: Next Wave of Faculty in Genomics Symposium. UC Santa Cruz is hosting a symposium dedicated to celebrating & highlighting outst….
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RT @DrugDiscovNews: Noncoding RNA has increasingly intrigued scientists as a diagnostic and prognostic tool for cancer. In this webinar, D….
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RT @RNASociety: We are excited to announce that the RNA 2025 Annual Meeting website is live! #RNA25. Limited rooms….
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RT @FLGenomics: Later on today we'll be hearing from 3 liquid biopsy researchers as they portray the latest research in detectable #biomark….
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RT @FLGenomics: Did you see our #liquidbiopsy webinar series? Join us next week to move beyond theory into practical advice, guided by 9 ex….
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RT @Joseph_DeSimone: About to kick off “The Early Detection of. Cancer Conference” in San Francisco cosponsored by @CanaryCenter @StanfordC….
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