Practical Neurology
@PracticalNeuro
Followers
18K
Following
177
Media
1K
Statuses
5K
Practical Neurology® magazine covers neurologic advances in epilepsy, stroke, dementia, movement disorders, headache, ALS, breaking neurology news & more.
Joined October 2011
Behavioral and psychiatric comorbidities are common in #epilepsy. Dr. Waldron (@dgsomucla) reviews evidence-based options, from SSRIs and antipsychotics, to #ADHD medications and ASMs that support mood and behavior. https://t.co/xtQY5sPuXN
@amepilepsysoc @UCLAHealth
0
0
3
DEE-SWAS remains difficult to treat, with heterogeneous presentations, variable responses, and urgent need for standardized approaches to therapy and outcome measurement. In a new review article, Drs. Rao (@lmraomd), Stowe, Kelley, Pavuluri, Liu, & Patel examine current
0
2
5
New adapted clinical practice #guidelines for the outpatient management of #TBI have been published in @AnnFamMed. https://t.co/dhZo8qlaCC
@biaamerica @AANmember @I_B_I_A @ACPIMPhysicians
practicalneurology.com
New adapted clinical practice guidelines for the outpatient management of traumatic brain injury (TBI) have been published in Annals of Family Medicine. D…
1
2
12
The @US_FDA has granted Fast Track Designation to #cladribine capsules (@EMDGroup) for the treatment of people with generalized #Myasthenia #Gravis. https://t.co/giHDfRn5On
@MyastheniaOrg @AANEMorg @AANmember #gMG
practicalneurology.com
The Food and Drug Administration (FDA) has granted Fast Track Designation to cladribine capsules (EMD Serono, Boston, MA) for the treatment of individuals…
0
1
16
Minimally invasive surgery within 72 hrs did not significantly improve 6-month disability or reduce 30-day mortality vs medical management alone in patients with supratentorial #ICH. Data published in @JAMANeuro. https://t.co/DRfDCp1Hml
@EVToday @WorldStrokeOrg @American_Heart
practicalneurology.com
According to results from the MIND clinical trial (NCT03342664) published in JAMA Neurology, minimally invasive surgery within 72 hours using the Artemis …
0
0
6
New findings from ancillary US #POINTER studies show structured lifestyle interventions linked to #sleep apnea, #neurovascular health, and #cognitive resilience in older adults at risk for #Alzheimer’s—#CTAD2025
https://t.co/jH2nm0pdyW
@ctadconference @alzassociation @AANmember
practicalneurology.com
New findings from 3 ancillary studies to the US POINTER trial (NCT03688126)—presented at the 18th annual Clinical Trials in Alzheimer’s Disease (CTAD) con…
1
2
6
The diagnostic accuracy of #Fujirebio's #Lumipulse plasma assay for #Alzheimer's pathology was assessed in a real-world cohort in a study presented at #CTAD2025. https://t.co/YhkL4yITnX
@US_FDA @ctadconference @AANmember @Alzassociation
practicalneurology.com
A study presented at the 18th annual Clinical Trials on Alzheimer’s Disease (CTAD) conference evaluated the Food and Drug Administration (FDA)-cleared and…
0
0
1
Treatment with the anti-#tau antibody #etalanetug in people with dominantly inherited #Alzheimer disease was associated with substantial reductions in the novel #biomarker eMTBR-tau243, indicating strong target engagement. #CTAD2025
https://t.co/Zunbh9xip4
@ctadconference
practicalneurology.com
Treatment with the investigational anti-tau antibody etalanetug (E2814; Eisai, Tokyo, Japan) for individuals with dominantly inherited Alzheimer disease (…
1
6
23
LM11A-31, a p75 neurotrophin receptor modulator, reduced p-#tau217 and preserved visuospatial function in #Alzheimer disease, with proteomic changes linked to synaptic biology. Data presented at #CTAD2025. https://t.co/awEdQmLfae
@CTADConference @alzassociation @AANmember
practicalneurology.com
Modulation of the p75 neurotrophin receptor using LM11A-31 (PharmatrophiX, Menlo Park, CA), an investigational small molecule agent, may slow disease-rela…
0
5
9
At #CTAD2025, Takeshi Iwatsubo, MD, PhD was honored as the recipient of this year’s Lifetime Achievement Award in #Alzheimer’s Disease Therapeutic Research. https://t.co/XxI4J8BB4p
@CTADconference @alzassociation @NCNP_PR
practicalneurology.com
Takeshi Iwatsubo, MD, PhD was recognized at the 18th annual Clinical Trials on Alzheimer’s Disease (CTAD) conference as the recipient of this year’s Lifet…
0
0
6
An oral #amyloid oligomer-targeting treatment was associated with cognitive and functional benefits in APOE ε4 homozygotes with MCI, according to results presented at #CTAD2025
https://t.co/gi3CaYwnzv
@Alzheon @CTADconference @alzassociation
practicalneurology.com
Results of a study evaluating the efficacy and safety of the oral amyloid oligomer-targeting agent ALZ-801 (valiltramiprosate; Alzheon, Framingham, MA) in…
2
3
9
In Lennox-Gastaut syndrome, #neuromodulation approaches—including #VNS, #DBS, and #RNS—offer substantial, durable #seizure reduction when medications fail. Dr Edmonds (@Edmondsbd) discusses these strategies in an article: https://t.co/QHE4pvsnt5
@amepilepsysoc @AANmember
2
4
27
An individual with progressive gait, cognitive, & cranial nerve symptoms had imaging consistent with intracranial hypotension, but repeated CTM/DSM found no #CSF leak. A fractured #cranioplasty implant was identified as the cause in a case report by Drs. Kushwah, Tiwari, Chhabra,
1
4
10
The @US_FDA has approved #Itvisma (@Novartis) for people aged ≥2 years with #spinalmuscularatrophy and an SMN1 mutation—expanding gene-replacement therapy options for #SMA. https://t.co/ct9ecoEPSA
@CureSMA @SMANewsToday @AANmember @ChildNeuroSoc
practicalneurology.com
The Food and Drug Administration has approved Itvisma (onasemnogene abeparvovec-brve; Novartis, Basel, Switzerland) for the treatment of people aged 2 yea…
0
2
10
Once-daily #asundexian + #antiplatelet therapy reduced #ischemic #stroke risk vs placebo with no rise in ISTH major bleeding in people with noncardioembolic ischemic stroke or high-risk TIA. https://t.co/QXKzMLuHjI
@WorldStrokeOrg @American_Stroke @EVToday
practicalneurology.com
For people with noncardioembolic ischemic stroke or high-risk transient ischemic attack (TIA), once-daily treatment with asundexian (Bayer, Berlin, German…
1
0
6
Strategies for managing drug-resistant #epilepsy are expanding with advances in less-invasive surgery—innovations in #SEEG, laser ablation, and #neuromodulation are broadening candidacy. Drs. Gallagher and Fallah (@a__fallah) review these technologies and their applications:
0
0
13
Updated consensus guidelines for the use of peripheral nerve stimulation in chronic #pain and certain #neurologic indications have been published by @ASPN_PainNeuro in @JPainResearch. https://t.co/2KyI2BnT3E
@AANmember
practicalneurology.com
A multidisciplinary expert panel convened by the American Society of Pain and Neuroscience has released updated consensus guidelines on the use of periphe…
0
2
12
Treatment with @VyeptiHCP (#eptinezumab; @LundbeckUS) was shown to significantly reduce monthly #migraine days vs placebo in adults with chronic migraine, according to data published in @JCephalagia. https://t.co/Hnq0VqFhDe
@ahsheadache @amfmigraine @AANmember
practicalneurology.com
Treatment with Vyepti (eptinezumab-jjmr; Lundbeck, Copenhagen, Denmark) was shown to significantly reduce monthly migraine days (MMDs) compared with place…
0
0
4
#Neuroinflammation plays a key role in refractory/super-refractory status #epilepticus. Drs. Silverman, Nagesh, Ho, and Santoro (@Drjonsantoro) outline the current understanding of immunotherapeutic and #immunomodulatory agents for the management of RSE. https://t.co/kpWMOkUrXm
1
7
24
The @US_FDA has granted 510(k) clearance to 2 devices developed by @Vesaliocom for use in peripheral and neurovascular #thrombectomy aspiration. https://t.co/otlhCFnYXU
@EVToday @AANmember @WorldStrokeOrg #Stroke
practicalneurology.com
The Food and Drug Administration (FDA) has granted 510(k) clearance to 2 devices developed by Vesalio (Plano, TX) designed to be used for aspiration durin…
1
2
2