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Practical Neurology

@PracticalNeuro

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Practical Neurology® magazine covers neurologic advances in epilepsy, stroke, dementia, movement disorders, headache, ALS, breaking neurology news & more.

Joined October 2011
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@PracticalNeuro
Practical Neurology
12 hours
Behavioral and psychiatric comorbidities are common in #epilepsy. Dr. Waldron (@dgsomucla) reviews evidence-based options, from SSRIs and antipsychotics, to #ADHD medications and ASMs that support mood and behavior. https://t.co/xtQY5sPuXN @amepilepsysoc @UCLAHealth
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@PracticalNeuro
Practical Neurology
2 days
DEE-SWAS remains difficult to treat, with heterogeneous presentations, variable responses, and urgent need for standardized approaches to therapy and outcome measurement. In a new review article, Drs. Rao (@lmraomd), Stowe, Kelley, Pavuluri, Liu, & Patel examine current
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@PracticalNeuro
Practical Neurology
4 days
Minimally invasive surgery within 72 hrs did not significantly improve 6-month disability or reduce 30-day mortality vs medical management alone in patients with supratentorial #ICH. Data published in @JAMANeuro. https://t.co/DRfDCp1Hml @EVToday @WorldStrokeOrg @American_Heart
practicalneurology.com
According to results from the MIND clinical trial (NCT03342664) published in JAMA Neurology, minimally invasive surgery within 72 hours using the Artemis …
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@PracticalNeuro
Practical Neurology
8 days
Treatment with the anti-#tau antibody #etalanetug in people with dominantly inherited #Alzheimer disease was associated with substantial reductions in the novel #biomarker eMTBR-tau243, indicating strong target engagement. #CTAD2025 https://t.co/Zunbh9xip4 @ctadconference
practicalneurology.com
Treatment with the investigational anti-tau antibody etalanetug (E2814; Eisai, Tokyo, Japan) for individuals with dominantly inherited Alzheimer disease (…
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@PracticalNeuro
Practical Neurology
8 days
LM11A-31, a p75 neurotrophin receptor modulator, reduced p-#tau217 and preserved visuospatial function in #Alzheimer disease, with proteomic changes linked to synaptic biology. Data presented at #CTAD2025. https://t.co/awEdQmLfae @CTADConference @alzassociation @AANmember
practicalneurology.com
Modulation of the p75 neurotrophin receptor using LM11A-31 (PharmatrophiX, Menlo Park, CA), an investigational small molecule agent, may slow disease-rela…
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@PracticalNeuro
Practical Neurology
9 days
An oral #amyloid oligomer-targeting treatment was associated with cognitive and functional benefits in APOE ε4 homozygotes with MCI, according to results presented at #CTAD2025 https://t.co/gi3CaYwnzv @Alzheon @CTADconference @alzassociation
practicalneurology.com
Results of a study evaluating the efficacy and safety of the oral amyloid oligomer-targeting agent ALZ-801 (valiltramiprosate; Alzheon, Framingham, MA) in…
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@PracticalNeuro
Practical Neurology
12 days
In Lennox-Gastaut syndrome, #neuromodulation approaches—including #VNS, #DBS, and #RNS—offer substantial, durable #seizure reduction when medications fail. Dr Edmonds (@Edmondsbd) discusses these strategies in an article: https://t.co/QHE4pvsnt5 @amepilepsysoc @AANmember
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@sentdm
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One API. Send messages on all channels.
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@PracticalNeuro
Practical Neurology
13 days
An individual with progressive gait, cognitive, & cranial nerve symptoms had imaging consistent with intracranial hypotension, but repeated CTM/DSM found no #CSF leak. A fractured #cranioplasty implant was identified as the cause in a case report by Drs. Kushwah, Tiwari, Chhabra,
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@PracticalNeuro
Practical Neurology
15 days
Strategies for managing drug-resistant #epilepsy are expanding with advances in less-invasive surgery—innovations in #SEEG, laser ablation, and #neuromodulation are broadening candidacy. Drs. Gallagher and Fallah (@a__fallah) review these technologies and their applications:
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@PracticalNeuro
Practical Neurology
18 days
#Neuroinflammation plays a key role in refractory/super-refractory status #epilepticus. Drs. Silverman, Nagesh, Ho, and Santoro (@Drjonsantoro) outline the current understanding of immunotherapeutic and #immunomodulatory agents for the management of RSE. https://t.co/kpWMOkUrXm
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