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Population and Statistical Genetics Group at UCPH Profile
Population and Statistical Genetics Group at UCPH

@PopGenDK

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Metagroup of labs working with population, medical, statistical, and conservation genetics at @uni_copenhagen

Copenhagen, Denmark
Joined March 2021
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@PopGenDK
Population and Statistical Genetics Group at UCPH
1 month
Highlights from this month’s #EPIC seminar series! Dinah Parker and @VizuetaJoel shared their fascinating work on #pathogenic #fungi 🍄and vision in #ants 🐜
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@PopGenDK
Population and Statistical Genetics Group at UCPH
2 months
So far we used the European #rabbit & #mountain #hare #assemblies.
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@PopGenDK
Population and Statistical Genetics Group at UCPH
2 months
Hi #popgen & #consgen we know #bimodal distribution in #sequencing data can happen but we see it in GC both pre- & post- #mapping in arctic #hares. We see the same trend when mapping to different reference genomes & in our own & published samples. Any insights are super welcome!
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@PopGenDK
Population and Statistical Genetics Group at UCPH
2 months
Alex Brown from the @TheKids_AU gave a great talk on indigenous genomics and how to address health inequality in these communities!.Thanks for joining us!
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@PopGenDK
Population and Statistical Genetics Group at UCPH
2 months
RT @EPICconference: Just a few more days left to sign up for the EPIC conference 2025! Join us in Aarhus this August 🥳.✍️Registration deadl….
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@PopGenDK
Population and Statistical Genetics Group at UCPH
3 months
This is a physical course but an online version will be available for those who can’t attend. We especially encourage students from African institutions to join online as this is offered as part of the African BioGenome Project Open Institute East&Central Africa Regional Workshop.
@PopGenDK
Population and Statistical Genetics Group at UCPH
3 months
Our population genetics PhD summer course 2025 @PopGenDK @Globe_UCPH is now open for registration! Featuring lectures & talks by Martin Sikora, @ShyamGlobe, @KBougiouri , Fernando Racimo, @idamoltke , @A_Albrechtsen. For more info:
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@PopGenDK
Population and Statistical Genetics Group at UCPH
3 months
Combining these two populations could reduce the otherwise high realized genetic load and increase species viability.
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@PopGenDK
Population and Statistical Genetics Group at UCPH
3 months
We also found that the gradual decline caused extremely low genetic diversity and strong purging of genetic load.
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@PopGenDK
Population and Statistical Genetics Group at UCPH
3 months
We generate a de novo genome sequence for a male saola and sequenced 26 recently discovered and near-extinct saola samples. We found two highly differentiated populations that diverged and gradually declined over >5,000 years ago.
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@PopGenDK
Population and Statistical Genetics Group at UCPH
3 months
We sequenced and analyzed the world's rarest large mammal, the #saola. That turned into a cool paper substantially increasing what we know about this elusive animal, its evolutionary history, population structure, and long-term decline. Check it out here:
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cell.com
The generation of whole-genome sequencing data from 26 saolas provides insights into the phylogenetic placement, population structure, historical decline, and genetic diversity in one of the world’s...
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@PopGenDK
Population and Statistical Genetics Group at UCPH
3 months
RT @EPICconference: Are you an evolutionary/population geneticist in Denmark? The EPIC conference is back and it will take place on 11-12 A….
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@PopGenDK
Population and Statistical Genetics Group at UCPH
3 months
Our population genetics PhD summer course 2025 @PopGenDK @Globe_UCPH is now open for registration! Featuring lectures & talks by Martin Sikora, @ShyamGlobe, @KBougiouri , Fernando Racimo, @idamoltke , @A_Albrechtsen. For more info:
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@PopGenDK
Population and Statistical Genetics Group at UCPH
3 months
Welcome back to our monthly #EPIC seminars! .We started today with our two speakers Evelyn Todd and @MartaCiucani talking about their research on #Scandinavian #wolves 🐺 and African forest #hogs 🐗 . Next seminar 🔜 May 21st.
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@PopGenDK
Population and Statistical Genetics Group at UCPH
4 months
PopGenDK is now of course also on Bluesky 🦋.
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@PopGenDK
Population and Statistical Genetics Group at UCPH
4 months
RT @NatureNV: Including under-represented groups in population genomics data could reduce inequalities in genetics-based clinical care and….
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nature.com
Nature - Population genetics for the Greenlandic Inuit.
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@PopGenDK
Population and Statistical Genetics Group at UCPH
4 months
RT @Nature: Nature research paper: Genetic architecture in Greenland is shaped by demography, structure and selection. .
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nature.com
Nature - We illustrate that including data from Greenlandic Inuit can greatly reduce inequity in genomic-based healthcare in Greenland and other indigenous Arctic populations.
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@PopGenDK
Population and Statistical Genetics Group at UCPH
4 months
The study is the result of a long and close collaboration with Steno Diabetes Center Greenland, Centre for Public Health in Greenland, and the University of Copenhagen. Also read the @NatureNV news and views: and News 🧵6/6.
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nature.com
Nature - Centuries of isolation have given Greenlanders a genetic profile that includes Arctic-specific variants.
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@PopGenDK
Population and Statistical Genetics Group at UCPH
4 months
Increased proportion of common variants results in twice as many high impact associations in Greenland compared to Europe. Many of these are Arctic-specific. The impact is measured as variance explained; a combination of allele frequency and effect size. 🧵5/6
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@PopGenDK
Population and Statistical Genetics Group at UCPH
4 months
The variant distribution is different: Overall fewer variants in the Greenlandic population but a larger proportion of common variants. At the same time, the additive genetic burden is comparable between all populations. 🧵4/6
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@PopGenDK
Population and Statistical Genetics Group at UCPH
4 months
Representation of Greenlandic summary data drastically improves the expected outcome of clinical screenings and the predictive power of polygenic scores. 🧵3/6
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