annarita
@PatriziLab
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Neurodevelopment@ChoroidPlexus@JuniorGroupdLeader@DKFZ
Heidelberg, Germany
Joined October 2011
Thank you @embojournal for sharing our story about the heterogeneity between choroid plexus tumors!.
Single-nucleus transcriptomes of 24K cells from disease-free human choroid plexus & choroid plexus tumors reveals heterogeneity & critical differences between epithelial cell compartment tumor microenvironment.Resource by @ccortical et al @PatriziLab @DKFZ.
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Excited to share a new paper from our group. A shout-out to Tony Hill (@ccortical ) that spearheaded the first single cell atlas of choroid plexus tumors!.Single-nucleus RNA-seq dissection of choroid plexus tumor cell heterogeneity | The EMBO Journal
embopress.org
imageimageThe genomic, genetic, and cellular events regulating the onset, growth, and survival of choroid plexus tumors remain poorly understood. Detailed single-cell expression transcriptomics...
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RT @MPIforBI: Meet the IMPRS-BI recruiting faculty: Nadine Gogolla @NadineGogolla and her group @mpi_psychiatry study how emotion states ar….
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Thank you @DKFZ ! We are very excited for this paper.
Choroid plexus tumors mainly affect toddlers. Scientists at DKFZ have now been able to show that a permanently activated important signaling pathway of intracellular communication is responsible for the development of these rare brain tumors. @PatriziLab.
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RT @DKFZ: Choroid plexus tumors mainly affect toddlers. Scientists at DKFZ have now been able to show that a permanently activated importan….
dkfz.de
Choroid plexus tumors mainly affect toddlers under one year of age. Scientists at the German Cancer Research Center (DKFZ) have now been able to show that a permanently activated important signaling...
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In this manuscript, we dissected key human molecular pathway underlying rare but devastating choroid plexus tumors and created the first 3D model of the tumor. I hope you will enjoy it. (4/4).
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I also want to thank all the amazing collaborators, many of them twitter less but all of them essential for this work. (3/4).
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A shout-out to Kim Hoa Ho that spearheaded the work and to @MTrapp13615 Trapp, two amazing researchers from my group. (2/4).
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Thrilled to announce our latest paper published in Neuro-Oncology and our first paper on choroid plexus tumor!.Activation of Wnt/β-catenin signaling is critical for the tumorigenesis of choroid plexus | Neuro-Oncology | Oxford Academic ( (1/4).
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Take a look at this super interesting paper from the @Acebron's group. @Acebron , @Anchel_91 , it was a pleasure to collaborate with you.
How does genomic mosaicism arise during development? We identified that embryo patterning signals not only readour genetic blueprints to build organisms, but they also play a critical role in their maintenance. A quick dive into our new paper 1/10
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RT @TheLuolab: Excited to share our paper in @PNASNews To our surprise, the ROSA26iDTR line showed diphtheria toxi….
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Thank you @laupellegrini and @Violesilvar for writing this interesting review with me I also want to thank again all the participants of the #ECSF for creating a great environment and sharing so many upcoming inspiring stories. Stay tuned!.
fluidsbarrierscns.biomedcentral.com
The European Choroid plexus Scientific Forum (ECSF), held in Heidelberg, Germany between the 7th and 9th of November 2023, involved 21 speakers from eight countries. ECSF focused on discussing...
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Congrats @Lena_Kutscher and Fred!.
I’m excited to announce our latest publication out now on bioRxiv, where we examine the role of the Elongator scaffold gene Elp1 in the developing cerebellum!
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RT @roland_imle: Check out our latest pre-print on a novel method 🧬 to model and study 🔬 #sarcoma under a fully competent immune system to….
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Here a fantastic paper from @Lena_Kutscher lab. Can’t wait to read it!.
In our first paper, we examine the gene regulatory networks underlying Group 3/4 medulloblastoma using a single-cell multiome atlas composed of >350,000 cells derived from 38 primary and relapse tumors.
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(1/2) we identified the molecular mechanisms underlying the excitatory and inhibitory synaptic localization of Neuroligin-3 and it includes the first ever imaging of human synapses. Enjoy the reading!.
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(1/1) This is a great way of ending 2023! This work started during my PhD (almost 16 years ago) and I want to thank the Poulopoulos lab for making this possible.
biologicalpsychiatryjournal.com
Neuroligin-3 is a postsynaptic adhesion molecule involved in synapse development and function. It is implicated in rare, monogenic forms of autism, and its shedding is critical to the tumor microen...
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RT @IBENS_ENS: 🥁Out on @Dev_Cell.👉Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage.🔗 https://t….
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