PatWilsonLab
@PatWilsonLab1
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Joined March 2023
Congratulations and completely expected to @victora_lab for becoming an HHMI investigator https://t.co/yZAXja8Qfj
hhmi.org
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Gut of newborns has unique bacteria that produce serotonin and promote the development of immune cells that may prevent allergic reactions to food and beneficial gut microbes, according to a preclinical study from @WCMpeds. https://t.co/3fnTZy14ZD
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Great job Josh! This was a "hunch" project that turned out to be so interesting once Josh dug in. In a nutshell: How do you balance the need for maximum antibody diversity and adaptability with the requirement for maintaining the ability of an antibody to express well?
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This is an amazing and intuitive approach as @stutangye has done so well for decades
Absolutely thrilled to lead a team of amazing CIs & AIs who together will aim to improve outcomes for ppl with inborn errors immunity
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A curated set of human immunoglobulin germline genes/alleles for better annotation of sequences encoding antibodies and antibody repertoires. It has potential to solve annotation problems you have not been aware of! #antibody #AIRRseq #repertoire
biorxiv.org
Analysis of an individual’s immunoglobulin (IG) gene repertoire requires the use of high-quality germline gene Reference Sets. The Adaptive Immune Receptor Repertoire-Community (AIRR-C) Reference...
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Antibodies are the product of evolution on two timescales: over millions of years in vertebrate populations, and within weeks of infection or 💉 in populations of B cells. We ask how those timescales interact in our paper out in @PLOSPathogens 🧵 1/n
journals.plos.org
Author summary Antibodies arise as B cell receptors encoded by the stochastic recombination of immunoglobulin genes. While those genes evolve over millions of years, the receptors themselves evolve...
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2/ Hi friends - please RT the following 2 ads. We are looking for talented people to join our HI3 team. Help us prepare for future pandemics
jobs.utoronto.ca
Administrative & Financial Assistant, HI3
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1/ Hi friends - please RT the following 2 ads. We are looking for talented people to join our HI3 team. Help us prepare for future pandemics!
jobs.utoronto.ca
Program Manager, HI3
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Many thanks to the thoughtful and comprehensive commentary from @ShivPillai4 on our paper led by @SirirukCh about broadly protective mAbs against SARS-CoV-2, both out today in the JCI: Comment: https://t.co/VlVfhaHjRU Paper: https://t.co/6vjkn52trk
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What a cool paper. I wonder if there are any active mutator mechanisms involved, analogous to AID in B cells.
Somatic mutations accumulate in “normal” non-cancerous tissues (blood, skin, liver). But why are mutant clones selected? Do they merely proliferate more, selfishly? Or can clones adapt to disease? Could they protect tissues? We shed light on this: https://t.co/Vu1d4U3stc 1/10
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Great to see you hanging out behind my apartment! Haha lets grab lunch or dinner or at least a beer: pcw4001@med.cornell.edu
🎶 “start spreading the news, we’re leaving today….” Off to NYC 🗽 today for HKS meeting at Rockefeller Uni. And catch ups w long time friends. Got some great travelling companions!!
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Check out our new paper led by @SirirukCh in collaboration with @HalfmannPeter from Yoshi Kawaoka's lab and Hejun Liu from Ina Wilson's lab describing a broadly cross reactive mAb to all SARS-CoV-2 variants. Overview: https://t.co/EfE28c7Ul6 paper:
news.weill.cornell.edu
A team led by researchers at Weill Cornell Medicine, the University of Wisconsin-Madison; Scripps Research and the University of Chicago has identified an antibody that appears to block infection by...
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Congrats Florian!
In case you missed it, Dr. Florian Krammer (@florian_krammer), co-PI of SEM CIVIC, was recently elected to the American Academy of Microbiology for his achievements in vaccinology and influenza biology! Check out our CIVICs News post to learn more:
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Celebrating the new boss, @SesmaLab ! With @VivianaSimonLab @jeanklim @mschotsaert and many others from our department. Cheers to Ana and to a bright future for Mount Sinai Microbiology! Thanks to Daniel Caughey for organizing this!
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Thanks Florian and Viviana for organizing it! I could not be happier about the opportunity to lead this AMAZING department! Feeling supported by this great group of colleagues is wonderful 🥰. Taking the torch from the great Peter Palese and carrying it forward! #SinaiMicro
Celebrating the new boss, @SesmaLab ! With @VivianaSimonLab @jeanklim @mschotsaert and many others from our department. Cheers to Ana and to a bright future for Mount Sinai Microbiology! Thanks to Daniel Caughey for organizing this!
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