A two-stage dication pool strategy using alkenyl thianthrenium intermediates has been developed for anti-Markovnikov hydrofunctionalization. This method differs from previous approaches in its...

It is known that NICS values can be misinterpreted to indicate aromaticity (or antiaromaticity) when measured in nonaromatic rings next to antiaromatic (or aromatic) ones. But how does this effect...

The synthesis of naphthannulated S-, O-, and N-heteroaryl compounds from isomeric ethynylbiaryl starting materials using a PtCl2-catalyzed cyclization reaction is reported.

A concise, bioinspired, and enantioselective synthesis of (−)-hunterine A, an unusual 6/7/6/6/5 pentacyclic natural compound, is reported through an aspidosperma precursor, employing a late-stage...

The partial reduction of esters to aldehydes is a fundamentally important transformation for the synthesis of numerous fine chemicals and consumer goods. However, despite the many efforts, limitati...

Structural Chemistry - Molecular complexes based on donor-acceptor interactions that involve π-systems with antiaromatic character are rarely studied. Herein, we report the synthesis of...

Aromaticity and antiaromaticity are pivotal concepts in chemistry, with significant implications for molecular properties and reactivity. In particular, thanks to their increased conductivity and...

Nature Synthesis - Metal–π interactions typically hinder metal-catalysed C–H functionalization reactions involving large π-conjugated systems. Now, an iron-catalysed...

The two-step, modular and scalable construction of amino-oxetanes for the purpose of bioisosteric incorporation has been developed using Katritzky's benzotriazole chemistry. This simple and user-fr...