TangLab
@NetPharMed
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Network Pharmacology for Precision Medicine Research Group @helsinkiuni @amchelsinki
Helsinki, Finland
Joined June 2018
RT @Dtrip4H10795: 👏 Presenting the amazing team behind the project!.Meet our consortium of partners spanning 23 organizations from 14 diffe….
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Great to be part of the consortium to develop digital twin models for cancer drug discovery! #digitaltwins.
✨ 📢 A new chapter begins! On January 1st, 2025, the DTRIP4H project, funded by the European Research Executive Agency (REA), took its first step toward a new initiative in Europe called “Decentralized Health Digital Twin Ecosystem consisting of Research Infrastructures”.
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Congratulations on defending your dissertation on the multi-omics analysis of drug resistance in #MultipleMyeloma, Alina! A firm testimony of endurance through hardship. Big thanks to the opponent Dr. @CascioneLuciano for making it happen! @ISBSIB @FIMM_UH @OrionPharma #oncosys
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It's great to know that our group has been granted funding from @Syopajarjestot @Syopasaatio! Thank you for entrusting us with our projects on combating drug resistance in cancer.
@Syopasaatio And congrats to #oncosys researchers @annimariav and @NetPharMed for research grants! As well as #oncosys young researchers @ntn_mai, Jun Dai and Sanna Pikkusaari for PhD grants.
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Consider to submit your next bioinformatics paper to GPB@GPBees!.
Exciting news! 🎉 Our journal "Genomics, Proteomics & Bioinformatics" (GPB) has achieved an impressive 2-year Impact Factor of 11.5 and a 5-year Impact Factor of 10.3! 🧬🧪 #Genomics #Proteomics #Bioinformatics #ImpactFactor Follow us on Twitter: @GPBees
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Warmest congratulations to @JehadAldahdooh on the successful PhD defense! Your hard work and persistence have paid off well. It has been a great honor to be the supervisor! Wish you all the success ahead!.
I successfully defended my PhD on Friday! Immense gratitude to Prof. Hong-Gee Kim for the insightful feedback and to Dr. Jing Tang and Dr. Ziaurrehman Tanoli for their unwavering support. Thank you to everyone who cheered me on throughout this journey @NetPharMed @UnivHelsinkiCS
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We are organizing the edition of 'Methodological developments in systems biology'. Your articles on the modeling of treatment responses and clinical outcomes are particularly welcomed! @Nature_NPJ.
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Finally out! We proposed a top-performing model to predict the survival of lung cancer patients for the Anti-PD1 treatment. @DR_E_A_M @bmsnews #Immunotherapy .Check the details of the model here:
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Let us rebuild hope through our small actions, even though it seems faint. Blessed are those who can give!.
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RT @AnnaVaharautio: Press release of our recent @NatureComms published study:.Sister cells uncover pre-existing resistant states in cancer….
helsinki.fi
In many cancers, such as ovarian cancer, each round of chemotherapy kills the majority of cancer cells, while a small population of them survives through treatment. These cells are typically more...
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Thrilled to co-announce our paper's acceptance in Nature Communications! 4-years of persistence in collaboration pays off finally😇. Stay tuned for more discoveries in cancer treatment!👍.
How do #cancer cells with resistant fates differ from the sensitive, already before the treatment? To answer this, we developed ReSisTrace, a cellular time-travel method that uses the similarity of sister cells to trace back pre-existing resistance.
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Nice to be part of the great consortium to implement FAIR principles for life sciences data! We are committed to the FAIR principles in our method development. @DrugComb @SynergyFinder
Celebrating the creation of #DataSpace for the #LifeSciences at the 4th & final EOSC-Life AGM (#eosclifeAGM23) in Brussels!.🥳.Partners shared tools, resources, & services, plus how these are being carried over into new projects like:.➡️@BYCOVID_eu.➡️@EOSC4Cancer.➡️@GDI_EUproject
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Generosity is a profound blessing that requires the courage/faith to act upon it. - summarized by ChatGPT😅.
Toxic cultures exploit generosity. Takers impose extra work on givers, and no good deed goes unpunished. Healthy cultures reward generosity. People protect givers from takers, and cream rises to the top. Helpfulness is not a weakness to target. It's a strength to safeguard.
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Congratulations on the success of the Compound Solubility Prediction Challenge! We would like to thank Wenyu, our exceptional PhD student, for his invaluable contributions to the organizing team!.
Congratulations 👏.
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Happy to learn that our paper has been selected for the PLOS Showcase collection! Understand the meridian theory in traditional Chinese Medicine by AI via @growkudos.
growkudos.com
Traditional Chinese Medicine (TCM) has been practicing unique and individualized methodologies for treating diseases, which have been developed over the course of many years of clinical experience....
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Happy to introduce a new R package for dose-response curve fitting! With drda, it is possible to fit models by the method of least squares, perform goodness of fit tests, and conduct model selection. User feedback is appreciated!
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Join our colleague's lab for exciting systems chemistry research!.
Interested in Supramolecular (Systems) Chemistry? Want to make functional chemical systems? Here is a three-year opportunity of working with us as a postdoc in these field.
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Well done @b_zagidullin for the interpretable prognostic modeling of endometrial cancer! Nice collaboration within the #oncosys program.
we published a paper! 1/n if you wanna do survival analysis, make sure to assess both model discrimination and calibration, using eg C-index and Brier score. Especially if you are using fancier ML methods.
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however, if a patient's TMB is higher than 242, then the antiPD1 treatment response is related to the PDL1 expression level (i.e. higher PDL1 expression suggests a better response to the antiPD1 treatment).
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