
Nucleic Acids Chemical Biology Lab, IIT Bombay
@NACB_IITB
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Research group of Prof. Pradeepkumar P.I. at @IITBombay. We specialize in the synthesis, biophysical, cellular and molecular dynamics studies of nucleic acids.
Mumbai
Joined May 2022
We are looking for two RAs having PhD degrees with good synthetic skills to do Nucleoside Chemistry for drug discovery projects. Prior experience in nucleoside Chemistry is preferred but not necessary. You may send your CV with research summary to pradeepkumar@iitb.ac.in.
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RT @HoebartnerLab: #SAMURI is a new #ribozyme for RNA-catalyzed labeling of RNA. It uses a new cell-permeable SAM analogue and generates a….
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Our new work in collaboration with the group of Prof. Kiran Kondabagil at IIT Bombay @KiranKondabagil .Human Translesion Synthesis Polymerases polκ and polη Perform Error-Free Replication across N2-dG Methyleugenol and Estragole DNA Adducts
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Work carried out in collaboration with @SGSrivatsan1 Lab. Probing juxtaposed G-quadruplex and hairpin motifs using a responsive nucleoside probe: a unique scaffold for chemotherapy - now published in Chemical Science
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Our new paper published in @jbiolchem .A collaborative effort with Gagnon Lab and @DamhaLab .Binding to the conserved and stably folded guide RNA pseudoknot induce.
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Our work on G-quadruplex have been published in @BiochemistryACS .Targeting Parallel Topology of G-Quadruplex Structures by Indole- Fused Quindoline Scaffolds
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Bisindolylmaleimide Ligands Stabilize c-MYC G-Quadruplex DNA Structure and Downregulate Gene Expression @BiochemistryACS .
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