Adam Mulkern
@MulkernAdam
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Postdoc, MacLean lab, high-throughput experimental evolution, AMR 🧬 @UniofOxford
Oxford, England
Joined November 2015
Excited to share something from my previous postdoc with @mgalactus, a collaboration with the @JoergLab using lab evolution to see how different bacterial species develop resistance to programmable antibiotics: https://t.co/894LEV1Oeg
biorxiv.org
The rise of antimicrobial resistance (AMR) among human pathogenic microbes is a serious threat to global health, calling for the development of novel treatment strategies. Antibiotics based on...
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Still buzzing after the @MicrobioSoc meeting on 'Understanding and Predicting Microbial Evolutionary Dynamics' last week. It was great to connect with so many people who share the same type of science. Big thanks to the organisers for the opportunity to present my research too!
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Had a short but sweet visit to Zürich to speak at @ETH_en. Many thanks to @phagemuffin and @AHarms485!
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What a month...I spent June in the US at the @CSHL Advanced Bacterial Genetics course and then the @GordonConf Molecular Mechanisms in Evolution! I met so many cool people along the way — special shoutout to my course lab partner, Max!
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Hopped over to Northern Ireland last week to give a talk at @QUBelfast for their AMR seminar series. Thanks very much to @WheatleyRM, @LindaOyama, and @sharonhuws for hosting me!
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Wrapped up 2024 with the @TypasLab in Heidelberg @embl, doing some evolution experiments with @StefanBassler. Had an incredible time and looking forward to an exciting year of science in 2025!
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Stress-testing #asobiotics…🦠 @MulkernAdam & @mgalactus from TWINCORE, in collaboration with #HIRI’s @JoergLab, have employed in-vitro laboratory evolution to study how different bacteria develop resistance to programmable antibiotics. Check out their preprint to learn more. 👇
We used in-vitro laboratory evolution to "stress test" the next generation class of antibiotics based on antisense oligos ("asobiotics"). Head over to our new preprint to find out more! (links in the next tweets)
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Big shoutout to these 3 from the MacLean Lab, currently in SF, who just launched Evolvere BioSciences on @ycombinator! 'Making next-generation antibiotics that outsmart bacterial evolution' Take a look and drop them an upvote!
ycombinator.com
Y Combinator created a new model for funding early stage startups. Four times a year we invest in a large number of startups.
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Published today in @EvolLetters 🎉🎉 Antibiotic resistance alters the ability of Pseudomonas aeruginosa to invade bacteria from the respiratory microbiome https://t.co/WDcZ92TAmX A short thread 🧵:
academic.oup.com
Abstract. The emergence and spread of antibiotic resistance in bacterial pathogens is a global health threat. One important unanswered question is how anti
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Had a fun day visiting @AdamWinnifrith at @TheCrick and got to check out their epic lab setup!
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After an amazing few years in Germany, I'll soon be starting a postdoc in the MacLean lab @UniofOxford 🧬 Thanks to @mgalactus for the mentorship and I'm very excited for what's ahead!
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The esteemed FEMS Summer School for Postdocs returns, inviting promising postdoctoral researchers in microbiology to partake in a transformative experience. It provides unparalleled opportunities for personal and professional growth. #FSSfP Apply Now: https://t.co/4DmFnH11en
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Our manuscript describing our tool panfeed has now been published in Microbial Genomics (@MicrobioSoc): https://t.co/BFkC17cyIP Head over to our lab website for a quick explainer:
microbiologyresearch.org
Here's a new preprint from the lab presenting panfeed, a tool to improve interpretability of k-mer based microbial GWAS, led by @HanNeb1337
https://t.co/vc4vQJNl3R
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Grateful for the opportunity to share my work @microbesNG popup 🙏🏻
🎥Here's @MulkernAdam's fab flash presentation 'The impact of E.coli genetic background on antimicrobial resistance evolution' showing collateral #AMR resistance 😬😨 https://t.co/TDkBSZTSc9
@mgalactus
@TWINCOREtweets
@MHH_life
@helmholtz_HZI
#MNGPopUp #ECR #MicrobialGenomics
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Squeezing in some final experiments before the @FEMSmicro postdoc school in Split. Excited to meet everyone 🇭🇷
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Pleasure to give a short talk for the #MNGPopUp today at Manchester Uni, met lots of cool people too!
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Very grateful to present my poster at #EESMicrobiology 🧫 The discussions were very engaging and insightful but my eagerness to return to the lab has reached a whole new level!
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