Manuel Gutiérrez-Aguilar
@MitoManny
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Profesor de Bioquímica. Facultad de Química, UNAM.
Tlalpan, Distrito Federal
Joined June 2020
Beautiful paper. Scientists solved the structure of myosin—the protein that forms contractile filaments in muscle cells—in multiple configurations using Cryo-EM. They captured the entire power stroke action (where myosin pulls on actin to shorten the muscle) at4.4 Å resolution.
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Our lab at SLU Medical School seeks a postdoc interested in ion channel biophysics, mechanisms underlying neuropathic pain, and cardiac arrhythmia, supported by NIH grants on cardiac and neuronal ion channels:
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As XIST silences, the lncRNA MAYEX activates the X chromosome in reptiles —the Red Queen and White King of epigenetics! 🐉👑. Diversity in gene regulation at a glance! 🌿 Congrats @d_q_cortez! #lncRNA #Epigenetics
science.org
Long noncoding RNAs (lncRNAs) are essential regulatory elements of sex chromosomes that act to equalize gene expression levels between males and females. XIST, RSX, and roX2 regulate X chromosomes in...
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Job Alert! Our lab is recruiting a Postdoctoral fellow to work on the interplay between mitochondrial morphology, mb contact sites, mtDNA dynamics and quality control. Have a look if interested! @MRC_MBU @Cambridge_Uni
https://t.co/sJ0lINsD4G
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Just how big can proteins get? Wow! Learn more at https://t.co/rZjuFXgP1n
#biology #3D #science #animation #protein
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A breakthrough from the lab! A game-changer and the dawn of a new era in membrane and organelle biophysics and biology. We've generated giant organelle vesicles #GOVs with conserved biochemical activity. @AgenceRecherche @LP_ENS_ @ENS_ULM @NatureComms
https://t.co/2NByLYeSNI 1/6
nature.com
Nature Communications - The biophysical properties of cellular organelles are difficult to study directly. Here, the authors generate and characterize osmotically-expanded giant vesicles of several...
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La Academia Mexicana de Ciencias convoca a los Premios de Investigación para jóvenes 2024. 🔴 Consulta la convocatoria 👉 https://t.co/Ad8bzxRktf 🗓️ Cierre de convocatoria 👉viernes 14 de junio de 2024
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Explore ATP synthesis and proton transport in cellular bioenergetics, from fundamental structures to regulatory mechanisms and disease implications. Introducing our speakers sharing their research on ATPases (F-type, V-type) https://t.co/jUa3FeJISK
#bioenergetics #EBEC2024
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Just updated! We updated our massive database of funding opportunities for POSTDOC fellowships. Each entry (316!), we provide the $ amount, deadline, eligibility criteria, description, and link to funder. Download this database freely here: https://t.co/EbTahdzJ9X
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Going to #APS2024 @APS this week? Come by @KMccommis and my session on Friday at 1:30 pm 104BC. Searching for signals: Interorgan Metabolic Communicators that Control Liver Metabolism.
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🚨 Apply until 8th of April 2024! 📌 Bayer Foundation Fellowships in Agricultural Science, Drug Discovery and for Medical Sciences in Germany 🇩🇪 Applicants are eligible for up to 10,000€ in funding ... Please share and spread the word! For details visit: https://t.co/l2NCBykgYd
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🎉 Let's celebrate another milestone - we've now reached 100 registrations! Do you also want to join the bioenergetics community at EBEC2024? Register now - before Early Bird prices end in a few days! #EBEC2024
https://t.co/2Z6zhQW127
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Secure your spot at #EBEC2024 now and enjoy a fantastic 20 % discount on registration fees. 🐦 But hurry, Early Bird registration ends on the last day of the month! ⏳ Register now: https://t.co/qGwFELWTIp
#bioenergetics #mitochondria #chloroplasts
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We are thrilled that Prof. Hartmut Michel, Nobel Prize winner in Chemistry for the first crystal structure of a photosynthetic reaction center, will be a keynote speaker at #EBEC2024. See the stellar speaker line-up we have so far: https://t.co/kGLHX92vwP
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¿Alguna vez te has imaginado trabajando en un laboratorio y hacer investigación desde tu casa? Buenas noticias: ¡lo puedes hacer y bien fácil! Les comparto un artículo de divulgación que publiqué en la @rdu_unam sobre la ciencia y la cocina.
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Kitsis and Peixoto Labs demonstrate... mitochondrial ATP synthase is a negative regulator of the mitochondrial permeability transition pore | PNAS
pnas.org
The mitochondrial permeability transition pore (mPTP) is a channel in the inner mitochondrial membrane whose sustained opening in response to eleva...
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Thrilled to see this work out in @Cell_Metabolism! We found 1) glycine is CLEARED (not produced) by liver SHMT2 & 2) de novo synthesis flux from glucose of NEAAs serine & glycine is insensitive to dietary levels (homeostasis is by variable consumption!). https://t.co/ZRkfOJwVx7
cell.com
The amino acid glycine is obtained from diet or by folate-mediated enzymatic production from serine. McBride et al. report that the folate pathway in the liver operates in the reverse direction and...
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