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Meaghan Morris Profile
Meaghan Morris

@MeaghanOMorris

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Neuropathologist/Neuroscientist at Hopkins studying Aging, Alzheimer's and Neurodegeneration

Joined August 2021
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@rafeequemavoor
Rafeeque Mavoor
1 year
Free scientific illustrations for biologists! 😍 @NIH has released a library of 500+ free scientific illustrations to create figures, presentations, and illustrations! all freely available in the public domain. Retweet and spread the message! https://t.co/p1bD1kxO7H
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@HopkinsGiving
Johns Hopkins Giving
1 year
Dr. Charles Eberhart (@NeuroEyepath) has spent 15 years researching pediatric brain tumors to identify new therapies that will improve post-treatment outcomes. Visit https://t.co/H5XofgYvwr to learn more about Dr. Eberhart, @JHUPath, and support for his work. #FacultyFriday
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@RikOssenkoppele
RikOssenkoppele
1 year
Flortaucipir PET has limited ability to detect PART Very important study by the Mayo Clinic group using an impressive post-mortem dataset of 248 individuals who underwent Tau (and amyloid) PET ~2 years prior to death. Among many interesting results, this study convincingly
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@JHUPath
Johns Hopkins Pathology
1 year
Congratulations to Hopkins GI pathology @JBirkness for being selected as an @ASCP_Chicago 40 under 40! Vote for her here for the top 5: https://t.co/LtJv4fXEUW
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woobox.com
Recognize the brightest emerging leaders and innovators of pathology, laboratory medicine, and ASCP by voting!
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@ZhuBokai
Bokai Zhu
1 year
1🔬/ Excited to share our latest preprint led by @ShuxiaoC , @Shenggao10 , @GarryPNolan , @SizunJ , @ZongmingMa , and with help from @shaleklab, Scott and more! https://t.co/PhBbSrI1la
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@DenaDubal
Dena Dubal
1 year
We are hiring postdoctoral fellows to study the longevity factor klotho and brain resilience in aging and Alzheimer's – using cellular, molecular, behavioral, and bioinformatic approaches! Please DM me if interested. Example of our work is below:
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nature.com
Nature Aging - The authors found that klotho, a longevity and cognition-enhancing factor, can increase the levels of multiple platelet factors in plasma, including PF4. PF4 treatment, which...
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@MeaghanOMorris
Meaghan Morris
2 years
A wonderful celebration of great science and mentoring at the @_BrightFocus event at @SfNtweets 2023!
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@seokheo1
Seok Heo
2 years
Final version released. 'Experience-induced remodeling of the hippocampal post-synaptic proteome and phosphoproteome' - Thanks Taewook, @alexei_bygrave, Martin and @rhuganir
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mcponline.org
In BriefHeo et al. characterized the remodeling of postsynaptic proteome and phosphoproteome using quantitative proteomics and phosphoproteomics combined with subcellular protein fractionation and...
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@MeaghanOMorris
Meaghan Morris
2 years
Synaptic genes were specifically dysregulated in tau-positive neurons and gene expression changes were similar in PART and AD
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@MeaghanOMorris
Meaghan Morris
2 years
The newest preprint from our lab using spatial transcriptomics to identify transcriptional changes in neurons with tau pathology in Primary Age-related Tauopathy and Alzheimer's disease
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medrxiv.org
Background Tau pathology is common in age-related neurodegenerative diseases. Tau pathology in primary age-related tauopathy (PART) and in Alzheimer’s disease (AD) has a similar biochemical structure...
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@tinakim_neuro
tina kim
2 years
Excited to share the first paper from our lab! https://t.co/sqfHd5couA We engineered a new kind of time-gated calcium integrator, CaST, that can rapidly and non-invasively tag activated neurons in vivo with a small, biochemical handle. What makes this tool special and unique? 1/6
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@JHUPath
Johns Hopkins Pathology
2 years
Hippocampal synaptic alterations associated with tau pathology in primary age-related tauopathy Newly published by Hopkins pathologist @MeaghanOMorris and colleagues https://t.co/lHTEAcfOzA
academic.oup.com
Abstract. Primary age-related tauopathy (PART) is characterized by aggregation of tau in the mesial temporal lobe in older individuals. High pathologic tau
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@LizEGerber
Liz Gerber
2 years
Excited this is finally out! Mouse models of SYNGAP1-related intellectual disability | PNAS
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pnas.org
SYNGAP1 is a Ras-GTPase-activating protein highly enriched at excitatory synapses in the brain. De novo loss-of-function mutations in SYNGAP1 are a...
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@HopkinsKavli
Kavli NDI Hopkins
2 years
“Synaptic Dysregulation Associated with Tau Pathology in Aging and Alzheimer's Disease”. Thank you @MeaghanOMorris  for the engaging presentation and discussion at our monthly breakfast meeting.
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@Karisa_Schreck
Dr. Schreck
3 years
So excited to see our work characterizing #BRAF #glioma in adults finally out in the world! I couldn't have asked for a better partner-in-research than @wenyalindabi and collaborators @CPratilasMD @NeuroEyepath among others. https://t.co/NOY6bvBtrW @Nature_NPJ @hopkinskimmel
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@MeaghanOMorris
Meaghan Morris
3 years
I may be a little biased, but the images are beautiful!
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@ScienceofPD
The Science of Parkinson's
3 years
An unusual case of a 91-year-old man with a clinical diagnosis of #Parkinsons, but whose autopsy findings showed a ubiquitin-positive astrogliopathy without significant neuronal loss in the substantia nigra - from @MeaghanOMorris & @JohnsHopkins colleagues https://t.co/tud3LQhdNi
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