Martin Wühr
@MartinWuhr
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Thrilled to announce our new study in Nature Cell Biology! In collaboration with @brangwynnelab, we've discovered a large fraction of the proteome forms mesoscale biomolecular condensates:
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RT @JonikasLab: Congrats @KafriMoshe and team including @WPatena, @LianyongW, @ASirkejyan, @AsaelRoichman, @clairemcwhite, @MartinWuhr!.Sys….
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Thrilled to share our study with Z. Gitai, N. Wingreen & T. Silhavy. We measured degradation of ~3.2k E. coli proteins in various conditions, finding cytoplasmic proteins recycle under nitrogen-limitation. #Proteomics #ProteinTurnover #EcoliResearch.
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RT @PastelBio: Super-Resolution Mass Spectrometry Enables Rapid, Accurate, and Highly Multiplexed Proteomics at the MS2 Level | https://t.c….
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RT @JonikasLab: Excited to share our latest preprint: Systematic identification and characterization of novel genes in the regulation and b….
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RT @biorxivpreprint: Super-resolution mass spectrometry enables rapid, accurate, and highly-multiplexed proteomics at the MS2-level https:….
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RT @xianfeng_zeng: Glad to share some of my grad work. Using in vivo isotope tracing and proteomics, we quantified gut bacterial nutrient p….
biorxiv.org
Great progress has been made in understanding gut microbiome’s products and their effects on health and disease. Less attention, however, has been given to the inputs that gut bacteria consume. Here...
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Our preprint on identifying mesoscopic condensates on a proteome-wide scale is out, @brangwynnelab, @FelixKeber:
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Our paper on how proteins access the nucleus and regulate timing of transcription in early development is out on bioRxiv Great work from @thaonguyen0210 @AAAmodeo @GatlinLab #development #proteomics #xenopus #generegulation.
biorxiv.org
The development of a fertilized egg to an embryo requires the proper temporal control of gene expression[1][1]-[6][2]. During cell differentiation, timing is often controlled via cascades of transc...
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RT @nchembio: A new paper from Ralph Kleiner and co-workers @PrincetonChem developed a chemoproteomic strategy to profile RNA-modifying enz….
nature.com
Nature Chemical Biology - A chemoproteomic strategy called RNA-mediated activity-based protein profiling (RNABPP) was developed to profile RNA-modifying enzymes in live cells and uncover the RNA...
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Our paper on "Evaluating the Arrhenius equation for developmental processes" just came out in Molecular Systems Biology .Paper resulted from discussions during freshman "Integrated Science Curriculum". The first author was a student in this class.
embopress.org
Time‐lapse analysis of frog and fruit fly embryogenesis combined with mathematical modeling is performed to examine how well the simple Arrhenius equation predicts complex multi‐step biological...
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RT @JProteomeRes: TMTpro for complementary ion quantification: TMTproC enables accurate and sensitive quantification on the MS2-level. Pape….
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TMTPro is exquisitely suited for Accurate Multiplexed Proteomics at the MS2 level via the complementary ion approach:
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RT @imprs_mpicbg: Fully-funded PhD position available @brugueslab @mpicbg @csbdresden to work on Self-organization of biological structures….
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Our paper on using the simple Arrhenius Equation to describe temperature dependence of complex developmental processes is out on bioRxiv:
biorxiv.org
The famous Arrhenius equation is well motivated to describe the temperature dependence of chemical reactions but has also been used for complicated biological processes. Here, we evaluate how well...
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Our protocol papers on proteomics experiments in Xenopus are out:
link.springer.com
The oocytes, embryos, and cell-free lysates of the frog Xenopus laevis have emerged as powerful models for quantitative proteomic experiments. In the accompanying paper (Chapter 13) we describe how...
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