David Margolis
@MargolisLab
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https://t.co/9nqGlCuvB0 Neuroscience lab interested in imaging neural circuit activity in mice
Rutgers, New Brunswick
Joined May 2013
So happy to see this work out! We studied when brain connectomes can be used to accurately predict neural activity, and when they can't. Happy to chat more about it, please do reach out if interested. https://t.co/ZRTzBRpUV7
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How does the brain balance learning new things without overwriting what it already knows? Our new paper tackles this long-standing stability–plasticity dilemma during active navigation. With @Adrinnenberg from the @KarlDeisseroth lab. (1/8) https://t.co/vBZbzs73Qn
@lisa_giocomo
biorxiv.org
In novel environments, animals quickly learn to navigate, and position-correlated spatial representations rapidly emerge in both the retrosplenial cortex (RSC) and primary visual cortex (V1)....
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Must read: Cortical glutamatergic and GABAergic inputs support learning-driven hippocampal stability | Science
science.org
Flexibility and stability of neuronal ensembles are crucial features of brain function. Little is known about how these properties of local circuits are influenced by long-range inputs. We show that...
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Thrilled to share our latest work showing spatially segregated Ca2+ signals of NMDAR and mGluR5 have opposing effects to maintain synapse homeostasis, with implications towards rapid antidepressant action (1/3) https://t.co/eVx9VmKPWX
pnas.org
Major depressive disorder affects millions worldwide, yet current treatments require prolonged administration. In contrast, ketamine produces rapid...
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Our politics MUST become this again, if we are to survive as a country...
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Vaccines are not magic. None are perfect. Some work better than others. Some have serious and occasionally lethal side effects. We don’t understand the downsides of vaccines perfectly. Not everyone needs every vaccine. Some are pushed for profit. The regulatory system around them
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ICYMI: Good news! The House rejected the proposed 40% NIH funding cut. The bill released has NIH funded at $48 billion, almost identical to the Senate’s number of $48.7 billion.
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Taxpayers: you reap enormous rewards from your modest investment in scientific research. American science is in grave peril. https://t.co/qupotRQSAl
nytimes.com
They hoped to make tomorrow’s medicines. Then came Trump.
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I'm Jewish. I got my PhD in neuroscience from Columbia in 2014. The biomedical research isn't even on the same campus as the protests. The Joint Task Force to Combat "anti-Semitism" will go down in infamy alongside HUAC. It makes me sick.
Today #NIH is terminating more than $250 million in funding—including more than 400 grants—to Columbia University following directives from the Trump Administration’s Joint Task Force to Combat Anti-Semitism. The cancellations are due to Columbia University’s continued inaction
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NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report
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NIH funding grows the economy while saving lives!!! First Do No Harm!!! NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report via @forbes
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Also confirmed this from several sources. The T32 that supported my post-residency work at Columbia is now…gone. These illegal cuts will have a devastating impact on the development of new treatments #MedX #MedTwitter
NEW: Columbia has begun notifying faculty of cancelled grants. From an internal source there: “Grant cancellation notices flowing in now. Labs shutting down. Layoffs imminent. Faculty apoplectic at Katrina Armstrong for letting it get to this point. She has to fix this fast.”
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As far as I can tell, Khalil has still not been charged & his attorney/family still don’t know where he is. Any Jew who thinks this is going to start & stop with a few Palestinian activists is fooling themself. Our community is not an excuse to upend democracy & the rule of law.
The Trump admin is exploiting real concerns about antisemitism to undercut democracy: from gutting education funding to deporting students to attacking diversity, equity, & inclusion. As we’ve repeatedly said: this makes Jews - & many others - less safe.
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LISTEN TO EVERY WORD. YES IT IS 12 MIN BUT HE SPEAKS THE TRUTH
President Trump and Elon Musk’s funding cuts to groundbreaking medical research do NOT Make America Great. That’s why I’m on the Senate floor introducing a resolution pledging support for NIH & asking for immediate passage. Watch.
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Measles is surging in Texas, with the vast number of cases among unvaccinated people & kids—124 cases & 1 child dead. Now, @US_FDA has cancelled a meeting of experts to plan for next year’s flu vaccine. This Admin’s silence on the importance of vaccines is deafening,
An FDA vaccine advisory committee meeting that was set to discuss what flu strains to include in next season's flu vaccine has been canceled, multiple sources told ABC News.
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