
Luca Del Prete MD
@LucaDelPrete9
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HPB and Liver Transplant Surgeon - Policlinico Hospital, Milan, Italy; Research Fellow in Liver Transplantation at the Cleveland Clinic, Cleveland - OH
Italy
Joined November 2020
🎉 Our brilliant new #SurgOnc clinical fellows have already been at work for a month! Welcome to Toronto and the program @aleborghiMD 🇮🇹 @DrShellyLuu 🇨🇦 @julielaMD 🇨🇦 & Alberto Riojas 🇲🇽🌟
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Major step forward toward cure for diabetes in trial led by Dr Trevor Reichman, Director of Pancreas & Islet Transplant Program @UHNTransplant @UHN_Surgery @UHN_Research @UHN
nejm.org
Zimislecel is an allogeneic stem cell–derived islet-cell therapy. Data on the safety and efficacy of zimislecel in persons with type 1 diabetes are needed. We conducted a phase 1–2 study of zimisle...
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🧒🩺 New from Drs. @AmandaJensenMD & Carlos Esquivel in @LTxJournal: In pediatric liver transplants, choledochoduodenostomy (CD) had the fewest biliary complications—lower stricture & leak rates than traditional options. CD is safe & may be superior. 🔗:
journals.lww.com
struction in pediatric liver transplants. We hypothesized that CD is a safe alternative for pediatric liver transplantation. Between January 2017 and February 2024, 186 consecutive primary liver...
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IPMN 🍇 without HRS and long term risk of cancer development 🇯🇵 2.5k pts > 5 years surveillance 🫧 IPMN size and growth predict cancer within 5 years 🤏 MPD diameter at 5 years predicts cancer after 5 years https://t.co/dNeBthc6QU
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Pancreatic cancer, often linked to smoking, obesity and diabetes, is predicted to become the 2nd leading cause of cancer-related death by 2030. A recent Seminar discusses the need for novel therapies & future directions for research: https://t.co/IQNCCl8FJY
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Deceased donor liver utilisation & assessment, consensus guidelines from ELITA including practical considerations/recommendations on: 🚧 adverse outcomes to be used to define suitability for #transplantation with conventional SCS alone ⚖️ donor & graft factors to define liver
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Normothermic regional perfusion (NRP) boosts organ recovery, but ethical concerns slow adoption. A scoping freely downloadable review explores key debates on donor harm, consent, trust, & justice. Can ethical challenges be resolved? #TXPforAll #OpenAccess
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Update on Portopulmonary hypertension guideline by International liver transplantation society 📌Hemodynamic definitions 📌Management approaches 📌POPH MELD exception criteria 📌Long-term outcomes #livertwitter
https://t.co/lJFuzY9gF1
@AnjanaPillaiMD
@HowardTLeeMD
@LizzieAbyMD
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The hard part of the whipple is done 💪time for the H-J !!! But do not let the attention drop… it can be tricky! 😅 🎥 Video grading bile duct anastomoses during robot PD 🐸 Bile leak rate 7% predicted by video! 🤖 Tool for teaching / learning curve https://t.co/LLUg7rysIA
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Co-producing a health advocate intervention for pediatric liver transplant recipients using human-centered design @UCSFLiverCenter @DoctorSharad @johnbucuvalas @JVittorioMD
https://t.co/RwnYzv8C5M
journals.lww.com
pediatric liver transplantation. We used human-centered design methods, eliciting the perspectives of caregivers and transplant team members, to design a navigator role for pediatric liver transpla...
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ChatGPT-4 demonstrates strong accuracy in grading surgical complications using the Clavien-Dindo classification. While it holds promise for automating postoperative data analysis, human oversight is still critical. https://t.co/GmUWWYc0VV
journals.lww.com
and precise application in dynamic clinical settings is challenging. AI offers a potential solution for efficient automated grading. Methods: ChatGPT’s accuracy in defining the CDC, generating...
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Treating livers ex-situ before LT using a MSC bioreactor: ⛑️ avoid MSC direct administration 🎯 reduce IRI in LT pathway ☄️ organ NMP treatment with a proven multistep experimental approach A great collaborative study @policlinicoMI & @HPDsurgery
https://t.co/GsPni8a3KC
nature.com
Nature Communications - MSCs-based therapies have broad application potential in reducing ischemia/reperfusion injury, but their use for treating isolated organs before transplantation remains...
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Long term natural history of BD IPMN 🍇 beyond 10 years of follow-up 🧐 316 patients 🇺🇸 median FU 13 years 🚨 At 10 years 24% WF / 8% Malignancy 📈 Risk of cancer overall 9X population 🎞️ Dynamic evaluation needed to stratify risk! https://t.co/MNJmmYKbSq
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Thrilled that my project "Epa-Rity" has been selected for @FondCariplo grant 'Inequalities Research.' Because "réparer les vivants" requires more than just technology and medicine—it means ensuring access to care for everyone and identifying where the system falls short
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New Review - The liver–brain axis in metabolic dysfunction-associated steatotic liver disease https://t.co/SvLIg7642j
#LiverTwitter #MedTwitter
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🆕EASL Clinical Practice Guidelines on the management of #hepatocellularcarcinoma❗️ ✅Updated advice for managing patients with #HCC & comprehensive review of pertinent data Full text👉 https://t.co/IAMvBDv0CT
#CPGs
#LiverTwitter
@EASLnews
@EASLedu
@AleksanderKrag
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🆕EASL Clinical Practice Guidelines on #LiverTransplantation❗️ ✅Focus on developments since the previous EASL guidelines published in 2016 Full text👉 https://t.co/PhHhCpXCUv
#CPGs
#LiverTwitter
@EASLnews
@EASLedu
@AleksanderKrag
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REVIEW Zanuso V et al. The rapidly evolving landscape of HCC: Selecting the optimal systemic therapy. #LiverTwitter
https://t.co/vnLBr1FosF
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And best poster with dr. Loglio from BG Hospital in a collaborative study with @policlinicoMI . Thanks to all the colleagues that took part to the study! Especially to @LucaDelPrete9 and @elo_franchi
Great days at @#ELITASummit @ESOTtransplant, presenting our works on ACLF, talking all about viability assessment, meeting old and new friends. Best Oral for @policlinicoMI with @daniele_dondo!
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REVIEW Obesity management for the hepatologist—What to do, how to do it and why? by @kymwatt @mqkMD et al. #LiverTwitter
https://t.co/WrOY1h405f
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