With @GilbertLab , we designed a pipeline to study communications toward muscle stem cells during tissue regeneration. How do MuSCs re-quiesce? Check the work by our star students @GarciaPaulineJ & @Erik_Jacques_ in our new preprint. https://t.co/floBl7nDDj

I am delighted to share our newest paper. @GarciaPaulineJ found that Setdb1 is absolutely required for muscle tissue regeneration. This by keeping ancient viral elements silenced in muscle stem cells. @EJPRareDiseases @iNeuroMyoGene @AfmPresse

J'ai un dépôt ANR de Schrodinger🐈. J'ai un email qui accuse réception de ma soumission, et un autre email qui me dit que ma soumission ne sera pas évalué car pas reçu. À moins que cela soit une soumission normande🤨?

This work will be presented live, next thursday at the GRC Myogenesis meeting. If you are attending, you should read the preprint so you may (1) Ask well thought-after questions or (2) Skip my talk and go swimming/running instead 😉

Read our preprint, and send us your feedback 😃. We deeply thank to the funding by @EJPRareDiseases @Telethon_France and our collaborator @t_cheung .

ERV de-repression in MuSC leads to aberrant cytokine release in regenerating muscle. This perturbs the inflammatory cells invading the tissue, and leads to macrophage histiocytosis. We found these macrophages inside the myofibers, eating them...

We found Setdb1 expression by MuSCs is necessary for their amplification and survival. Without Setdb1, MuSCs re-express endogenous retroviruses; ancient DNA elements that shall remain silent.

Delighted to share our latest work on BioRxiv. During her PhD, @GarciaPaulineJ relentlessly studied the impact of removing the H3K9 methyltransferase Setdb1 in muscle stem cells. Strikingly she found Setdb1 is absolutely required for regeneration 1/n https://t.co/V6m2gVwE7l

Un poste de gestionnaire financier est à pourvoir au sein de l'INMG. Découvrez l'annonce ci-dessous 👇

You asked for it #myotwitter and @Erik_Jacques_ delivered! A new 3D assay to study regulators of muscle stem cell quiescence and niche repopulation principles 'in a dish'. Our easiest method YET! What questions will you ask?

Check out Nicolas Rose study, out in Biomaterials. He navigated between three labs/co-supervisors during his PhD, and yet successfully created very tiny 3D myotubes between pillars. This is a new tool to measure the force generated by a single human muscle cell in health/disease.

Very enthusiastic to participate to the 8th Cultured Meat conference starting Sunday in Maastricht. Looking forward to learn about the latest developments on how to grow edible muscle "in a dish".

⚠️Only a few weeks left to register to the @humancellatlas Development and Pediatric Cell Atlas Meeting in Paris🇫🇷 . November 20 - 22, 2022 .

Check out our new resource paper @iScience_CP showing dramatic changes in epigenetic and transcriptomic landscapes during muscle stem cell #quiescence exit and #aging. Congrats to @AnqiDong18 and colleagues! #myotwitter https://t.co/XrQlenavhD

FASEB conference on muscle satellite cells @MuSCandReg just started 😎 with @vahabsoleimani @GilbertLab @GarciaPaulineJ

LaLaurie mansion in New Orleans. The Dame was apparently a serial killer from the early 19th century. But her (rebuilt) mansion is a Hallmark of the french quarter.

Arrived in New Orleans, after so many delays. It only took 19hours from Toronto. Aaaaand... they lost my luggage! I have been expecting this 😭

On a completely unrelated topic, I learned today that while one can buy rhum at the airport duty free shop, it is absolutely forbidden to open it before one reaches his/her final destination. I was asking for a friend.

Also is someone connecting in Denver airport today? #nightmarishtravel

This morning, I arrived 3 hours and 30 minutes at the Toronto airport before my flight for New Orleans, and missed it due to spending 3 whole hours in line for the US customs. To colleagues going to @MuSCandReg meeting tomorrow: please be more prepared than me.