Yuval Nir 💔
@LabNir
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Studying sleep, anesthesia, neuromodulation, memory, and sensory processing, combining human and animal models, Tel Aviv University | @labnir.bsky.social
Joined February 2019
1/14 .How does sleep help memory? we developed closed-loop deep brain stimulation during sleep in human prefrontal cortex w/ timing based on hippocampal activity.TLDR: boosting hippocampus-cortex coordination improves memory.@NatureNeuro |
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Human hippocampal ripples align new experiences with a grid-like schema: Neuron
cell.com
Xiao et al. show that brief bursts of hippocampal activity (ripples) help the brain link new experiences into an internal “mental map.” During rest, ripples engage a medial frontal brain region that...
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Enhancement of Sleep Slow Wave Activity using Transcranial Electrical Stimulation with Temporal Interference
medrxiv.org
Slow waves mediate restorative functions of non-rapid eye movement (NREM) sleep. To enhance slow wave activity (SWA, 0.5-4 Hz) non-invasively, we employed a novel neuromodulatory tool, Transcranial...
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RT @CommsPsychol: Anticipatory eye movements during repeated movie viewing reveal when and what is remembered. Gaze patterns correlate with….
nature.com
Communications Psychology - Anticipatory eye movements during repeated movie viewing reveal when and what is remembered. Gaze patterns correlate with explicit reports, offering a method to detect...
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Anticipatory Eye Gaze as a Marker of Memory. Our new study presents a NO-REPORT method for studying episodic memory w/ eye tracking. Kudos to amazing team @FlavioSchmidig @YaminEtAl @omerxsharon @JonNir3 @CharanRanganath.
Happy and proud to finally see this out!.I am excited about our new approach to collect episodic memories independent of verbal report. Please reach out if interested!. It was a pleasure creating this monster with @LabNir @YaminEtAl @omerxsharon @CharanRanganath . img© Ana Yael
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How interesting! Activity patterns in individual neurons drift over time, even in subcortical sleep- and wake-promoting regions -- while populations remain stable. Beautiful work from @Tidis__ @CaroGHerrera: .
researchsquare.com
Correlative and causal evidence implicate distinct genetically-defined and evolutionary-conserved hypothalamic neurons in regulating wakefulness, non-rapid eye movement (NREM), and rapid eye movement...
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Closed-loop electrical stimulation prevents focal epilepsy progression and long-term memory impairment:.
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Sleep-like Slow Waves During Wakefulness Mediate Attention and Vigilance Difficulties in Adult ADHD.
biorxiv.org
Background Attention-Deficit/Hyperactivity Disorder (ADHD) is characterised by behavioural variability and heightened inattention associated with increased mind wandering (MW) and mind blanking (MB)....
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RT @NatureNeuro: Cortical closed-loop electrical stimulation can prevent pathological hippocampal-cortical communication and preserve long-….
nature.com
Nature Neuroscience - Pathological neural communication drives the spread of the epileptic network and contributes to memory impairment in focal epilepsy. The authors show that closed-loop...
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Sleep need–dependent plasticity of a thalamic circuit promotes homeostatic recovery sleep | Science
science.org
Prolonged wakefulness leads to persistent, deep recovery sleep (RS). However, the neuronal circuits that mediate this process remain elusive. From a circuit screen in mice, we identified a group of...
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Had a brilliant time at #SXSWLondon organized by @CNSfund discussing the future of sleep - issues ranging from monitoring health, through unique interventions, recording EEG via earbuds, to disengaging from ruminations falling asleep & lucid dreaming @lustenca @simon_joe50
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So very proud of our own @OmerBenBarak1 who received the prestigious Sieratzki PhD scholarship for her research on pupillometry and gaze imaging in closed eye conditions, well done Omer!
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Astrocytes. we haven't been paying enough attention:.
science.org
Locus ceruleus (LC)–derived norepinephrine (NE) drives network and behavioral adaptations to environmental saliencies by reconfiguring circuit functional connectivity, but the underlying synapse-le...
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RT @marcaurelbusche: Our latest work, published in @CellCellPress, identifies a rare soluble #tau species in human #Alzheimer’s brain that….
cell.com
In mouse models, tau impairs neuronal complex spike bursting and associated network processes in hippocampus CA1 alongside CaV2.3 downregulation. Soluble high-molecular-weight tau species drive these...
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Our latest: SleepEEGpy - check it out !.
Tired of spending months teaching every new student how to clean and analyze sleep EEG? 🧠💤.We were too. @LabNir .That's why we built SleepEEGpy- a simple open-source pipeline to make sleep EEG research faster, easier, and standardized! 👇.
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RT @DavidOmer_: Nachum's new book Natural Neuroscience is out! A fresh take on how brains work in the real world—well worth a read. https:/….
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A time window for memory consolidation during NREM sleep revealed by cAMP oscillation: Neuron
cell.com
Sleep is crucial for memory formation. Deng et al. find that cAMP levels in mice oscillate with a 1-min cycle during slow-wave sleep, and hippocampal activity at the peak of these oscillations is...
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