Miccio lab
@LabMiccio
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gene therapy, genome editing, lentiviral vectors, sickle cell disease, beta-thalassemia, red blood cell, hematopoietic stem cell
Imagine Institute,INSERM,Paris
Joined May 2022
Happy to share our work published today on Nucleic Acid Research @NAR_Open :."Dissecting the epigenetic regulation of the fetal hemoglobin genes to unravel a novel therapeutic approach for β-hemoglobinopathies".
academic.oup.com
Abstract. Beta-hemoglobinopathies are severe genetic diseases caused by mutations affecting the production of the adult β-globin chain. The clinical severi
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There's still time to register for the CRISPR-Cas9 workshop - registration has been extended. Participate to the second CRISPR-Cas9 workshop in the beautiful city of Sorrento, featuring renowned scientists from around the globe!
meetings.embo.org
A decade of groundbreaking research on bacterial CRISPR-Cas defence systems has culminated in the development of revolutionary editing technologies. This tool has been exploited to create transgenic …
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RT @LabMiccio: We're thrilled to be organizing a CRISPR-Cas9 workshop in the beautiful city of Sorrento, featuring renowned scientists from….
meetings.embo.org
A decade of groundbreaking research on bacterial CRISPR-Cas defence systems has culminated in the development of revolutionary editing technologies. This tool has been exploited to create transgenic …
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It was great to attend the first Genother summit 2025 meeting!Thank you Genother #genother . #GenoTherSummit . #genetherapy
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We're thrilled to be organizing a CRISPR-Cas9 workshop in the beautiful city of Sorrento, featuring renowned scientists from around the globe! .
meetings.embo.org
A decade of groundbreaking research on bacterial CRISPR-Cas defence systems has culminated in the development of revolutionary editing technologies. This tool has been exploited to create transgenic …
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Bye-bye #ASGCT2025 . It was a pleasure to chair the session on Advanced editing tools with Tj Cradick @NucleaseLab organized by the genome editing committee!@ASGCTherapy
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Check out our recent collaborative study on how inflammation influences stem cell engraftment in beta-hemoglobinopathies!. Bravo Steicy Sobrino Emmanuelle Six !!!.
nature.com
Nature Communications - The DREPAGLOBE lentiviral-based gene therapy for sickle cell disease is safe. However, its efficacy depends on the number of infused hematopoietic stem cells (HSCs) and...
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RT @Nature: A paralysed man can stand on his own after receiving an injection of neural stem cells to treat his spinal cord injury. https:/….
nature.com
Nature - Another man also regained some movement, but two others experienced minimal improvement.
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RT @PhBaptiste: L’@InstitutImagine est un exemple de réussite à la française dans le domaine de l’innovation en santé. L’IHU incarne l’exce….
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Happy to participate in the Keystone symposia "Precision Genome Engineering: Translating the Human Genome to the Clinic" #KSGenomeEng25 and share our latest results!
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RT @SETGyC: 🧬 @GeneHumdi COST Action, con la colaboración de @SETGyC, organiza el curso "Optimizing Gene Editing with Advanced Omics: Safet….
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Read our commentary on Cell Stem Cell: Two is better than one: Advancing gene therapy protocols for enhanced safety and efficacy.@CellStemCell .
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RT @g1_guillermo: some heads up, . The @EMBO Workshop "CRISPR-Cas: from biology to therapeutic applications", to be held from 2–5 November….
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Med Sci (Paris) 2025; 41 : 33–39.Une approche CRISPR/Cas pour traiter les β-hémoglobinopathies.A CRISPR/Cas approach to β-haemoglobinopathies.Megane Brusson* et Annarita Miccio**.
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RT @CrisprMedicine: 𝐍𝐞𝐰 𝐓𝐫𝐢𝐩𝐥𝐞-𝐀𝐜𝐭𝐢𝐨𝐧 𝐂𝐑𝐈𝐒𝐏𝐑 𝐓𝐞𝐜𝐡𝐧𝐨𝐥𝐨𝐠𝐲 𝐄𝐧𝐚𝐛𝐥𝐞𝐬 𝐒𝐢𝐦𝐮𝐥𝐭𝐚𝐧𝐞𝐨𝐮𝐬 𝐆𝐞𝐧𝐞 𝐀𝐜𝐭𝐢𝐯𝐚𝐭𝐢𝐨𝐧, 𝐑𝐞𝐩𝐫𝐞𝐬𝐬𝐢𝐨𝐧, 𝐚𝐧𝐝 𝐃𝐞𝐥𝐞𝐭𝐢𝐨𝐧 𝐢𝐧 𝐏𝐫𝐢𝐦𝐚𝐫𝐲 𝐇𝐮𝐦𝐚𝐧 𝐓 𝐂….
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Treating Sickle Cell Disease: Gene Therapy Approaches | Annual Reviews -
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RT @celltherapynews: Drs. Giulia Hardouin, Annarita Miccio (@LabMiccio), and @MeganeBrusson review breakthroughs in gene addition- and geno….
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Discussing Gene therapy for β-thalassemia: current and future options
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RT @InstitutImagine: Nouvelle publication scientifique ! Importance des études de sécurité et d'efficacité pour le traitement de la drépano….
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Discussing "Ex Vivo Genetic Modification and Hematopoietic Cell Transplantation" at the ASH Scientific Workshop on Genomic Toxicities of Gene and Cell Therapies @ASH_hematology
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