Kordasti_lab
@KordastiL
Followers
716
Following
1K
Media
157
Statuses
612
The main focus of our research group is the role of immune system, in particular Tregs, in the pathophysiology of Myeloid malignancies, including MDS & MPN.
London, England
Joined February 2020
Mesenchymal stromal cells from JAK2V617F myeloproliferative neoplasms support healthy and malignant hematopoiesis in a humanized scaffold model in vivo https://t.co/IJsEUBTe5n
#MPNsm #MDSsm #microenvironment @Hemasphere_EHA @KordastiL @harrisoncn1 @TheCrick @MPN_Hub @MDS_Hub
1
2
16
Our new paper out! β¨ We built a humanized mouse model of JAK2-mutated MPN by embedding patient MSCs & progenitors in a gelatin scaffold to recreate bone marrow. It preserves disease genetics and enables research on immune response & immunotherapies. π Link in first comment
3
1
21
Check out our paper looking at QRISK3 score as a predictor of thrombotic risk in MPN patients . Great collaborative work led by Patrick Harrington and Andrea Duminuco @ADuminuco #mpn
https://t.co/H9ps0VGdjW
nature.com
Leukemia - QRISK3 score is predictive of thrombotic risk in patients with myeloproliferative neoplasms
0
2
15
#EHA2025 #EHA25 || πGreat to meet up with all-stars π myeloid malignancy research @doctorpemm @Ramikomrokji Dr. Santini @KordastiL @sanamloghavi ||
0
1
29
#EHA2025 #EHA25 ||| Wonderful catch-up with @doctorpemm @KordastiL & @sanamloghavi | #MPNSM #inflammation #hemepath
0
3
34
Excited to share our @nih_nhlbi work led by Alice Wu in collaboration with @KingsCollegeLon published in @NatureComms using scRNAseq and CyTOF to explore pathophysiology of immune #aplasticanemia pre and post IST. https://t.co/xswXd8cIKy
@NealSYoung1 @bhavishap29 @KordastiL
1
7
26
Dear friends, This account will be deactivated and deleted in about a month. Join us on Bluesky Social for updates and discussions. See you there! πΏπ¬ https://t.co/QthLhn1wkF
0
0
1
Friends, I am at a loss of words for how devastating it would be to lose the entire intramural #NIH program. Some of the biggest medical and scientific breakthroughs have come from scientists in the NIH Intramural program. #SaveTheNIH
https://t.co/UlkCDfHD7f
science.org
Policy follows firings of tenure-track scientists and suspension of training programs
46
475
1K
Immune-monitoring of myelodysplastic neoplasms: Recommendations from the #i4MDS consortium https://t.co/YedhhlvgCM
@Hemasphere_EHA @KordastiL #MDSsm
@aamdsif @ic_MDS @MDS_Hub @MDSAlliance @MDSFoundation
0
8
26
In past 2 days, we had our annual #i4MDS meeting in The Hague. Great discussions with colleagues about the role of the immune system in MDS and novel findings. Three years ago, when we founded this group, I never expected this level of progress and collaboration. Truly delighted.
0
6
20
It was great to have @Dr_AmerZeidan in our annual #i4MDS meeting at the Hague (virtually). He gave an excellent talk on the future of ICI in #MDS. Many thanks Amer for the great talk!
0
1
5
I spent the past three days in Bergen university, Norway, giving a lecture for the Haemato-Oncology group and conducting a research methodology workshop for medical students. I thoroughly enjoyed the scientific discussions and exchanges with the students and colleagues.
1
0
19
Huge congratulations to Antonio Curti and his team for this remarkable work. The research proposes EV-based liquid biopsy as a noninvasive tool for metabolic stratification, and targeting the glutathione-GPX4 axis and metabolic dependencies in #AML. https://t.co/h7hjo08Xa6
nature.com
Nature Communications - The role of metabolism in acute myeloid leukaemia (AML) onset remains to be explored. Here, the authors explore the metabolic landscape of AML cells and the signature of...
0
4
17
How can T cells revolutionise cancer treatment? Discover how in the latest episode of the Hema Now podcast, featuring Dr @SKordasti, @KordastiL, @KingsCollegeLon: https://t.co/J7lZX1fzr8
0
3
3
In this podcast, hosted by Dr. Jonathan Sackier and published today in the EMJ, I discussed various advancements in the field of cancer immunotherapy. At the beginning, I also talked a little about myself and how I became interested in this field. https://t.co/yff8DZ9Xum
emjreviews.com
Discover the immunobiology of Myelodysplastic syndrome and Aplastic anaemia, the role of CD4+ T cells in myeloid malignancies, and more.
1
3
18
Happy New Year! Wishing you all a wonderful year ahead, filled with joy and happiness ππ
1
0
12
And the last clinic before Christmas! Wishing you all a very happy holiday season!
0
0
11
Excellent talk from colleague Zhijie Wu who presented our labβs data on T-cell clonality and dynamics after IST in #SAA. #ASH24 @ASH_hematology @NealSYoung1 @KordastiL @bhavishap29 @nih_nhlbi
0
1
7