🚨 New paper alert 💥 We show @IBDJournals how #IBD-associated 🧬 SNPs can switch 🔄 upstream signals, leading to patient-specific susceptibilities ⚡ ✅ Helping to explain patient heterogeneity ✅ Linking genetics w/ environmental & microbial signals 👉 https://t.co/O2ECV2aphH

@ibdleuven @bverstockt @NickPowellLab @modoslab @johanne_brooks @ImperialMDR We were honored to get an Editorial at the journal highlighting our study and its implications. We are grateful for the great Claudio Fiocchi and Dimitrios Iliopoulos for their insightful summary. https://t.co/nUEb76y8a5

Our findings show how genetic variation reshapes cellular signaling in #IBD (see two patient-specific networks 👇), providing a foundation for #PersonalizedMedicine. Collaborative work with @ibdleuven @bverstockt @NickPowellLab @modoslab @johanne_brooks 🙌 From @ImperialMDR

🔑 Key insights: ✅ Most IBD SNPs lie in non-coding regions, roles unclear until now. ✅ Using our iSNP systems genomics pipeline, we showed SNPs alter TF binding and rewire upstream signaling in patient-specific manner. ✅ Common upstream changes driving IBD identified.

Very happy to announce that I got promoted to Associate Professor (Reader) at Imperial College London @ImperialMDR 🍾 I am grateful for all past and current team members, all our collaborators and direct colleagues for their support and talent.

🎉 The revised version of CORNETO, our unified Python framework for knowledge-driven network inference from omics data, is published in peer reviewed form 🔗 Paper: https://t.co/l2UH0ae9jA 📖 News & Views: https://t.co/0mouNBKXic 💻 Code: https://t.co/DdyOYKh1u9 🧵 Thread 👇

This #GutMicrobes paper has been a nice collaboration w/ Shiv Radhakrishnan, James Alexander & Prof Horace Williams. Our side was led by @martonolbei. Great to finally analyse omics data of a real inception #IBD cohort to capture meaningful signals/markers not masked by therapy.

Excited to share that I started a new chapter in my career as a Teaching Fellow at Imperial College London! I really enjoy teaching, and look forward to the opportunities and challenges ahead.

5 years cancer-free. At 37, I was diagnosed w/ #colorectalcancer. Caught early, treated, & now in remission 🙌 To mark this milestone, I’m running the #RaceForLife 10k on 29 June in Oxford for @CR_UK Please sponsor my run & get checked! It saves lives. 👉

Why to come to this workshop? ✅ Meet & talk to world leading experts, usually not present at the same conference ✅ Grant writing sessions ✅ Career development & mentoring ✅ Collaborative, inclusive, fun ✅ Perfect for PhDs, postdocs + clinician-scientists #ECRs @Y_ECCO_IBD

🔬 The workshop brings together leading scientists & ECRs working on: • Inflammation, IBD, cancer, neurodegeneration • Organoids & gut-on-chip • Host–microbe interactions • Network biology & multi-omics • Precision medicine #Organoids #IBD #Microbiome

🎯 Few places left for a unique scientific event this summer! Join us at the next Signaling Workshop, July 28–31 in Visegrád, a Renaissance town on the Danube. • Real-world group projects • Knights’ Tournament ⚔️ • Childcare program for families 👶 🔗

Huge thanks to sponsors @STEMCELLTech, @QkineBio, @MIMETAS_3D & @TheCrick for making this event possible! 🙌 Next up: join the WORC LION group @OrganoidSphero1 to turn this momentum into real collaboration, training, & exchange programmes! 🧫🤝 #Organoids #BetterTogether

Keynotes from @GrayCampLab & @paolodecoppi highlighted #organoids in evolution & translation. Talks from @GutOrganoid, @christophertape, @VivianLiLab & me showed London’s strengths: organoid biobanks, co-culture, cancer models, and multiomics. #GutOnChip #Microbiome #IBD #Cancer

🦁 The LION had its first roar! We launched the London gastroIntestinal Organoid Network (LION) with 120+ researchers from @imperialcollege, @KingsCollegeLon, @ucl, @TheCrick, @QMUL & beyond. With 40+ on the waiting list, the excitement for gut organoid science is real! 🔬🔥

Inspiring few days on how to identify mechanisms for #MyalgicEncephalomyelitis (ME) / Chronic Fatigue Syndrome. #SystemsBiology session w/ @modoslab #Cytokines w/ @martonolbei #organoids & new #Gutonchip + #microbiome platforms @ImpOrganoid @ImperialMDR Thanks for @Invest_in_ME

Mapping cell-cell communication and its changes upon inflammation and infection Marton Olbei Imperial College London #brmec14 #mecfs #InvestinMEresearch

Calling all lions & lionesses to submit your abstract to this unique launch event of LION, the London gastroIntestinal Organoid Network https://t.co/aCVG8JCFJx by 16 May Be part of the first roar of LION! 🦁 Organised by @imperialcollege @KingsCollegeLon @ucl @TheCrick on 9 June

Final program for this year's Signaling Workshop is live! https://t.co/yoYye2niW0 🎟️ Only 10 spots left! 💡Unique mix of speakers rarely at the same event 🌍Topics: #IBD, #Microbiome, #Organoids,#SystemsBiology, #PrecisionMedicine 🔗Register till 28 April:

Great news! 🍾 We are excited to host + support the @HFSP fellowship of @InezRoegiers at @ImperialMDR @ImperialMed This project to bioprint microbes & #organoids will have revolutionary impact on how we study host-microbe interactions & on the role of the #microbiome in #IBD! 👏