Excited to share our latest work published in @Nature, by grad student @mirazul302, currently on the job market. We uncovered clonal dynamics relating normal to tumor cells using natural and synthetic genetic changes. #SingleCell #DevBio #CRISPR #CRC #HTAN

So glad to be spending a few days with @SKDevStemCell @SK_GGB @SickKidsNews to share great science and friendship! Beautiful Blue Mountain Venue.

Congratulations to @K_Harsim from @KenLauLab for winning the Poster Prize at the Beatson International Cancer Conference 2025! Thanks to @MolOncology for sponsoring this prize #BICC2025

Thank you to @CRUK_SI and @DrPipDunne for a wonderful experience in Scotland for #BICC2025. Congratz to @K_Harsim for receiving the outstanding poster award!

Congratulations to @skotomorph for winning this year's Mentorship Excellence Award! Honored to have such an inspiring individual in our midst! @VUBasicSciences

Proud of @Paige_N_Spencer and @mirazul302 for completing their PhD journeys with me last week. The best is yet to come!

Thank you to Vlaams Instituut voor Biotechnologie (VIB) for inviting me to the conference on Immune Niches in Cancer & Inflammation in beautiful Bruges. Feels like walking into a Disney story. Incredible science!@cell #INCI25

Thank you Yonsei-Severance for hosting a wonderful conference : YONSEI HTAN SCL G1's Lab K-BioX global summit 6. Have great respect for Korean science and tech. @tae_hwang @IamLinghua @DrMingyaoLi

Better late than ever. Awesome to catch up with colleagues and friends at #AACR25! @DrPipDunne

Vanderbilt EBC symposium. Get-together with the polyclonal crew w/ Doug Winton and Christina Curtis.

What drives region-specific Crohn's disease (CD)? Our preprint uncovers how Chlamydia, a pathobionic microbe, triggers ascending colon inflammation, further promoting investigation of conditionally bad-acting microbes in inflammatory diseases #IBD #chronic https://t.co/W5DRbI8mEn

The first successful recruit for the newly launched CCSB: Dr. @tae_hwang from Dept of Surgery - https://t.co/QMNhEQ0HOp #HTAN

Excited to be part of this exciting initiative in systems biology, data science, and AI: https://t.co/3Fg1pKoUCT

Happy Holidays from our lab to yours. Here is to a safe and productive 2025! (Courtesy of @w_janney ).

Everyone should have a Paige clone in their lab! Congratulations to Dr.@Paige_N_Vega for successfully completing her PhD. She is off to MIT. She will be sorely missed. I am proud of her and what we accomplished together! @VanderbiltCDB

Truly excited to start our new journey in @NCIHTAN phase 2, this time with @SpragginsLab using imaging mass spec in 3D #CRC. https://t.co/yxR6gaKElH

Very grateful to receive continued support from the Stanley Cohen Innovation Fund. Congratulations to fellow 10th floor EBC colleague @The_Choi_Lab. https://t.co/t6OQStaG4J

Thank you to all collaborators! @SpragginsLab, @Coffey_EGFR, Lauren Ehlrich , @VUBasicSciences, @vandy_biostat

MILWRM also detected consensus tissue domains in ST data from differently oriented sections of mouse brain. It is an easy-to-use python package that can be run on several mIF images and ST samples together.

MILWRM can identify consensus tissue domains across multiple samples, which is useful for identifying broad tissue classes when studying diseases like cancer. We show this in colon pre-cancer mIF data where MILWRM identified distinct tissue domain in sessile serrated lesions.

By doing so, MILWRM also includes extracellular information missing from cell segmentation analysis. In the paper we demonstrate how MILWRM assisted identification of tissue domains that capture the anatomical features of colon, lymph node and kidney.