Conor J Kearney
@Kearney_Lab
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Head, Molecular Immunology Laboratory, ONJCRI, Melbourne, Australia.
Melbourne, Australia
Joined July 2016
Excited to share our latest pre-print identifying TAK1 as a tumour intrinsic checkpoint that limits CTL-derived cytokine-induced cell death and immunotherapy responses. Brilliant collaboration between @Kearney_Lab @ONJCRI and @Vervoort_Lab @WEHI_research. https://t.co/tqcD2QBozx
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A post doc position is available in my lab @ONJCRI 🔬 If you are interested in investigating tumour immune escape using genomics and CRISPR please get in touch!!!
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We’ve known about tolerant CD8+ T cells for >25 yrs – but what are these cells?! Prematurely exhausted, stalled effectors, or something else? Our latest @ImmunityCP paper takes a deep dive into this question with some unexpected results, including a link to cancer… (1/)
Online now: The CD8+ TÂ cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects
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A Post Doc position is available in my Molecular Immunology lab (MIL) @ONJCRI. Co-appointment with @Vervoort_Lab @WEHI_research. If you are interested in new tech (CRISPR and singe cell) to study Cancer Immunology please get in touch!
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🎉 Let’s celebrate #anticancer champions, Conor @Kearney_Lab and Matthias @lab_ernst for securing a collective $4.3 million in @nhmrc funding! Get ready for a new era in cancer treatment options as the team at ONJCRI unite against cancer. Are you with us?
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We celebrated St Patrick's day with a pot of research gold! Dr Conor Kearney and collaborators unveiled ground-breaking findings that significantly contribute to our #Anticancer fight - a finding as thrilling as a jig on a Temple Bar! 🍀 Read more https://t.co/CzLWxcbVQO
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@KalliesLab and I are excited to share our latest study in @NatImmunol dissecting the heterogeneity and function of VAT Tregs. Huge effort from @Santiago_VaTo and Kevin Man @TheDohertyInst @UniMelbMDHS @ONJCRI @LIMSLTU Thanks to all our collaborators!! https://t.co/SK4xHmsH5A
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PRMT1 acts as a suppressor of MHC-I and anti-tumor immunity
cell.com
PRMT1 negatively regulates STAT1-driven MHC-I expression and can be targeted to enhance the efficacy of cancer immunotherapy.
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Congrats to Coner Kearney, Mario Djajawi, and @PijpersLizzy for this beautiful study. Awesome collaboration between @PeterMacRes and @ONJCRI.
cell.com
PRMT1 negatively regulates STAT1-driven MHC-I expression and can be targeted to enhance the efficacy of cancer immunotherapy.
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🥳 Great news! $1.2M @nhmrc Ideas Grant awarded to CI’s Conor Kearney #ONJCRI, Stephin Vervoort @WEHI_research & associate investigators to identify new immune checkpoint targets in #cancer to improve #immunotherapies Congrats @Kearney_Lab @Vervoort_Lab @latrobe [1/2]
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Two weeks left to apply to join the @Vervoort_Lab at @WEHI_research supported by @SnowMedical Do you want to explore the unknown in the field of gene regulation? Do you love #Genomics #CRISPR #Transcription? Then we are looking for you 🫵 Plz share 📥 https://t.co/iRYaibWIYC
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Congratulations to @PijpersLizzy and supervisors @JohnstoneRicky @Vervoort_Lab, a fantastic body of work for a PhD thesis!
Always great when a PhD student from the lab presents their completion seminar. Congrats to @PijpersLizzy from the @JohnstoneLab @PeterMacRes for your hard work, dedication and skill in completing your PhD lab work. Thanks to @conorkearney88 and @Vervoort_Lab for cosupervising.
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Thanks Austin Medical Research Foundation @AustinMRF1 for #grants to further research into breast cancer and predicting colorectal cancer patient outcomes! https://t.co/A6hUG3K0Pg Well done Camilla Reehorst, @conorkearney88 @drbhupinderpal, Jimmy Chan, Amr Allam, Zhipeng Cao
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ATG9A prevents TNF cytotoxicity by an unconventional lysosomal targeting pathway
science.org
ATG9A promotes the LC3-independent lysosomal detoxification of the cytotoxic complex IIa to prevent TNF-induced apoptosis.
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Over at the tumour immunology session- a fabulous presentation by PhD student, @LizzyPijpers from the @PeterMacCC 🙌 #ASI2022MEL
@WEHI_research
@ONJCRI @conorkearney88 @Stephintje @rickyjohnstone
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Really excited about this project!!!
Very excited about this innovative project involving @JohnstoneLab @Stephintje @conorkearney88 and @pfizer. The power of collaborations between @PeterMacRes @WEHI_research and @ONJCRI in Melbourne……Can’t wait to get cracking!
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More thought provoking presentations from A/Prof Michael Hildebrand, A/Prof Rachel Davey, Dr Kylie Quinn @ONJCRI #NBS2022 today 👏. Top analogy of the day from A/Prof Peter Mount - “Acute Kidney Injury is like a car breaking down” @Unimelb @latrobe @RMIT @TheFlorey @TheFlorey
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Congrats to my stellar lab member Izzie, + Edwin & @Stephintje, on their latest pub in @cddpress identifying new epigenetic regulators of B cell fate! @WEHI_research @WEHI_Postdocs
https://t.co/bDIuyzQCmX
nature.com
Cell Death & Differentiation - Epigenetic modulators of B cell fate identified through coupled phenotype-transcriptome analysis
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