Kevin Alexander
@KMAlexanderMD
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Physician-scientist, advanced heart failure and transplant cardiologist, amyloidosis specialist
Stanford, CA
Joined April 2018
This was fun to do with Dan Judge, @MasriAhmadMD @KMAlexanderMD
It’s almost time! ⏰ Join HFSA tonight for CardioAbstracts: New ATTR-CM Data, a live discussion unpacking newly presented clinical trial findings and what they mean for practice. 🗓️ October 29 | 5:30 PM ET 💬 Ask questions. Gain insights. Stay ahead of the latest in heart
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Acoramidis 📉 cumulative CV outcomes in #ATTRCM vs placebo, w/ numerical differences by month 1 & 📈 through month 30 (53 events avoided/100 pts). Nearly 1/4 of events occurred in the first 6 months, underscoring the need for timely Tx https://t.co/MOo8sZYmtF
#HFSA2025 #JACC
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@KMAlexanderMD presents data on acoramidis reduction of CV mortality/outcomes in ATTRibute and its OLE #ESC2025
#CardioTwitter
#MedIQESCCongress
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High Sensitivity Troponin for Contemporary Risk Stratification in Wild-Type ATTR Amyloidosis @KMAlexanderMD #AHAJournals
ahajournals.org
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Read our latest contemporary review on polygenic risk in venous thromboembolism. Polygenic risk score improves risk prediction, guides anticoagulant use, and helps tailor prevention. @AqamarMD @MananPareekMD @KMAlexanderMD Link:
rpthjournal.org
Venous thromboembolism (VTE) is a significant global health concern, with >1 million cases annually in the United States, making it a leading cause of preventable hospital-related deaths. Advances in...
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Proud to share our review on transthyretin amyloid cardiomyopathy! https://t.co/giACwEptSR We break down the current treatments, what’s in the pipeline, and what’s next. @UreyTony @UCSDCardiology
link.springer.com
Cardiology and Therapy - Transthyretin amyloid cardiomyopathy (ATTR-CM) is a progressive disease caused by the deposition of insoluble amyloid fibrils derived from misfolded transthyretin (TTR)....
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Another disappointment for #AL #amyloidosis #depleters: CARES didn’t meet its primary endpoint. What exactly was the prespecified subgroup that showed benefit? 🤔 Does this mean anything for #ATTR depleters? Time (and full data) will tell.
reuters.com
AstraZeneca's experimental therapy anselamimab did not meet the main goal of a late-stage study for the treatment of a rare condition that causes a buildup of protein deposits in the body, the...
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🎉 Kudos to Dr. Alexander for an outstanding presentation! 🧩 The "Thick Heart Puzzle" — Cardiac Amyloidosis vs. HCM. Insightful, impactful, and eye-opening! ❤️🩺 #InnovationsincardiologyHawaii @KMAlexanderMD
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🥳🙌 Congratulations to @Stanford_HF's graduating HF fellows Ibrahim Alfaris, Leon Zhou, and Ricardo Chi Li! Great work and best of luck‼️ @KiranKhush1 @SunnyVMD @EldrinL @alyelezaby @KMAlexanderMD @stanfordctsurg @euanashley @Ron_Witteles @ATSandhu @vnparikh
@ISHLT @HFSA
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New research featuring #StanDOM's @graciafahed, @KMAlexanderMD, @Ron_Witteles, Francois Haddad & Gabriela Spencer-Bonilla, highlights how socioeconomic disparities hinder early detection of transthyretin cardiac amyloidosis. https://t.co/Cfxe3bk3Oz
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👑 @MariannaFonta11 new data at #HeartFailure2025 from #ATTRibuteCM Exploring effects of acoramidis on functional capacity & QOL in patients with variant ATTR-CM 6-minute walking distance - 87m (!) mean increase KCCQ health status gain - 20pt (!) mean increase #MedIQHF2025
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How do patients with #ATTRCM die? New insights from #ATTRibuteCM at #HeartFailure2025 @KMAlexanderMD @MasriAhmadMD #MedIQHF2025
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New data from #ATTRibuteCM presented at #HeartFailure2025 Intriguing analysis by @KMAlexanderMD High-affinity TTR stabilizer acoramidis potentially associated with lower risks of AF/AFL events in #ATTRCM
#MedIQHF2025
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Establishing repeatability, reproducibility, & accuracy of imaging metrics is paramount for use in pivotal multicenter #amyloidosis trials. https://t.co/iShF56NNLn
#JACCIMG #cvImaging #CardioTwitter #CardioOnc @DorbalaSharmila @KMAlexanderMD @MicheleEmdin
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Incredibly proud of the @Stanford_HF team, with so many impactful presentations at #ISHLT2025. Honored to work with such a talented group! @JeffTeuteberg @ErikHenricksen @CODonnell1130 @KMAlexanderMD
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19a) A final analysis from #ATTRibute_CM, led by @KMAlexanderMD, evaluated the stability & improvement in #NYHA class on acoramidis vs placebo. At 30mo, 35.9% of pts in the #acoramidis group and 53.0% of pts in the placebo group had worsened in NYHA Class or had missing values.
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Please share this exciting and interactive Amyloid case based seminar w/your fellow Amyloid champions and trainees. @BrettSperryMD @maz_hanna @MelissaLyleMD @MarthaGrogan1 @MasriAhmadMD @YevgeniyBr @MKIttlesonMD @Ron_Witteles @Rfonsi1 @KMAlexanderMD
Amyloidosis Mysteries: Cracking the Toughest Cases 📅 Tuesday, May 13, 2025 12:00 PM EDT Join us for an engaging online case study session with insights from expert discussions on diagnosing of amyloidosis. #MedicalEducation #Amyloidosis #ISA_Amyloidosis
https://t.co/lZTwH5DhgY
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Systemic efforts are needed for early diagnosis, enabling all populations to benefit from breakthrough treatments. For more details: 1) https://t.co/OYnbifyB7I 2) https://t.co/DZuZKSwoTX
@KMAlexanderMD @Ron_Witteles @Katrina488555
@JACCJournals #JACCHF
jacc.org
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🫀Therapeutic options for ATTR-CM are expanding rapidly, yet diagnostic delays remain significant.👇Our latest @JACCJournals studies uncover geographic, socioeconomic and racial disparities in timely ATTR-CM diagnosis and outcomes, across both Stanford and national CDC cohorts.
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