Infection & Immunity
@InfImmAg
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Microbial pathogenicity, host defence, immunity to infection, vaccines and immune-therapy. BSI Infection and Immunity Affinity Group.
United Kingdom
Joined May 2015
Important differences. AN EPIDEMIC is a disease that affects a large number of people within a community, population, or region. A PANDEMIC is an epidemic that’s spread over multiple countries or continents. ENDEMIC is something that belongs to a particular people or country.
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In this study, @MiyuMoriyama et al investigate how well SARS-CoV-2 variants of concern (VOC) suppress MHC I needed for recognition by cytotoxic T cells. This question is important to understand how well the virus limits CD8 killing 🧵(1/) @biorxivpreprint
https://t.co/TLvnB7NotN
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From ONS death certificates, 16,000 people have died so far in the Omicron wave. While this is far lower than the pre-vax Alpha wave in Jan 2021, it's almost the same as died during Delta wave - despite vaccination & in shorter time period. High nums of infections matter 6/14
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@jneill This is how Boris Johnson’s government wants to “live with Covid”, leaving thousands of emergency patients waiting for hours. This is criminal, but the public seems fine with it or maybe they don’t understand the issue.
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99% of the world now lives in polio-free countries. The finish line for #polio eradication is in sight Join the Global Polio Eradication Initiative to learn about the support needed to deliver on our promise to #EndPolio by 2026 Register now: https://t.co/VuX4WWNxQU 🗓️26 April
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📅 Tuesday 5 April 18:30-19:30 Join our next event with Prof Sharon Peacock and Dr @KaterinaGalai, who will talk about the impact of genome sequencing on the #COVID19 pandemic response in the UK and beyond. #CamFest @CamInfectDis Register now👇 https://t.co/lcURX55cje
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A #booster #COVIDvaccine is the best protection against severe #COVID19 🦠💉 With the spring booster programme underway, it’s a good time to explore why booster doses are safe & effective at enhancing the immune response 💪 Download this infographic 👉 https://t.co/tSUTqKxF27
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We're joining forces with @TheCrick & @NatImmunol to celebrate the #DayOfImmunology with a free hybrid event 🥳 An expert panel will explore why the #immunesystem attacks the body’s own cells & tissues in #autoimmune diseases on 28 April 💭 🗓 Register: https://t.co/q9RnhqmM5I
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THREAD: State of the pandemic in the UK (esp England) Hospital admissions are best way to compare waves right back to start - we are on wave 7 now! 4 of which happened since last July. So cases & admissions are rising - why? does it matter? where are we 2 years in? 1/13
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New work from LJI researchers makes it possible to tell the difference between T cell responses to #SARSCoV2 infection and T cell responses to a #COVID19 vaccine https://t.co/b3tStCfjds
@cellhostmicrobe
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Immunologists agree 100%. Vaccines work and vaccines are everyone's best chance of not becoming I'll from #Covid19 and vaccines also reduce the chance of someone else being infected. Please get vaccinated (1 + 2 + booster). #VaccinesWork
#BoosterJab
#GetBoosted
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“a virus does not become endemic just because a government wants it to happen, and certainly not at a point when infections are running at their highest ever level.” Sky News
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🆕💥💥💥The first and the best peer review article to date from SA scientists that describes the genomic molecular profile, mutations and early transmission dynamics of ⭕micron, highlighting Transmissibility, immune evasion and infectiousness #IDTwitter
https://t.co/ulgCrEEgcq
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Coronavirus: excellent public engagement resources from @britsocimm including on vaccines https://t.co/PipZpLgUgo
#Covid19UK
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Nonetheless numbers are really rising. Tuesday 868, Weds 1,275, and since I posted the first tweet Thursday’s figure has come out: 2,465. Which means the wave chart now looks like this:
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Potential implications for antibody responses: 5/ https://t.co/A6978YOjOP
Here's how mutations in #SARSCoV2 Nu variant (B.1.1.529) will affect polyclonal and monoclonal antibodies targeting RBD. These assessments based on deep-mutational scanning experiments; underlying data can be explored interactively at https://t.co/uP3IKvnDw0 (1/n)
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Breakdown of mutation profile: 4/ https://t.co/ik3oAk7Tsc
Took a look at the spike mutations in B.1.1.529 this evening, and colour coded them (details below)...there is...not much green.🧵
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The brand new UK #COVIDVaccine #Research Hub celebrates the huge contribution of UK scientists to our understanding of how #vaccines can best protect us from #COVID19 🦠💉🔬 Funded by @UKRI_News Find out more here 👉 https://t.co/nIrKoc2Tg4
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🆕 Now online in our new edition of #Immunology News – we get the inside scoop from BSI member Dr John Tregoning @DrTregoning about his new book Infectious! Find out how the book pays homage to the #scientific innovations of the past century 👉 https://t.co/Hp0rWic9uV
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