M. Brent Hawkins
@Homeobox
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Post doc in the Harris lab. Genes, bones, and fishes. Harvard Medical School // Museum of Comparative Zoology // Boston Children's Hospital. he/him/his.
Boston, MA
Joined May 2009
Can a fin (still) become a limb? . To find out, @fishyskeleton, @khenke2012, and I performed genetic studies in the zebrafish & found the remarkable hidden ability of fins to become more limb-like. Look below for a quick summary of our findings!.
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RT @ceri_weber: Looking forward to #2025SDB #2025ICDB this week! I'll be presenting on my mammal tail research during the 'Role of Scaling….
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RT @Dev_journal: The sclerotome is the source of the dorsal and anal fin skeleton and its expansion is required for median fin development….
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RT @NicholsLab: This a special one for us, I found this weird mutant without a dorsal fin close to 15 years ago while a postdoc with Chuck….
journals.biologists.com
Summary: The sclerotome, an embryonic structure within the somites, is the source of median fin cells and is reduced in smoothback mutant embryos, which do not form dorsal fins as adults.
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RT @ceri_weber: I am very excited to share the first preprint from my postdoc with @UCSDCooperLab ! Read along to learn about tails and ver….
biorxiv.org
Despite the functional importance of the vertebral skeleton, little is known about how individual vertebrae elongate or achieve disproportionate lengths as in the giraffe neck. Rodent tails are an...
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Holy cow! A beautiful phenotype matched with excellent analysis! Congratulations @TanakaY_evodevo and all the authors. Zebrafish fins can be elaborated across multiple axes to produce new skeletal patterns
Our new paper about the fin evolution in teleosts is finally out. Fin elaboration via anterior-posterior constraint by hhip on Hedgehog signaling in teleosts
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RT @biorxiv_evobio: Plasticity in the pectoral fin skeleton is induced by altered foraging regime in a South American cichlid https://t.co….
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RT @tetsuyanakamu: Fish shoulder girdle is weird and fascinating evo-devo model. Multiple cell populations come together and make one compo….
nature.com
Nature Communications - The embryonic origins of the pectoral girdle in fish remain unexplored. Here they show that the zebrafish pectoral girdle develops as an amalgam of four distinct cell...
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Latent ancestral developmental potential.
Starring Frank Grillo, Werewolves will be unleashed in theaters December 6, 2024. "A supermoon event triggers a latent gene in every human on the planet, turning anyone who enters the moonlight into a werewolf for one night."
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"I would like to begin by thanking The Organizer".
Don’t miss this exceptional event: Self-Organization in Biology: 100 years of the Spemann-Mangold Experiment. Abstract submission deadline extended to May 17th. Slots for talks still open. Spread the word! #DevBio #CellDifferentiation #StemCells
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The implied homology between cloaca and digits is intriguing 🤔.
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RT @HintermannAurl1: I am super excited to see our work on #bioRxiv 🤩!! Special thanks to @Duboule and @chasebolt, it was a lot - of fun -….
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RT @Duboule: Of limbs, fins, genitals and cloaca; the unexpected evolution of a regulatory landscape @BioRxiv 🙏to Aurélie @Hintermannaurl &….
biorxiv.org
The transition from fins to limbs has been a rich source of discussion for more than a century. One open and important issue is understanding how the mechanisms that pattern digits arose during...
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RT @NeilShubin: Looking for a fully paid postdoc, with research funds, in developmental genetics, embryology and/or paleontology in my lab?….
biologicalsciences.uchicago.edu
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