Niklas Geue
@GeueNiklas
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Walter-Benjamin Fellow at FU Berlin; Mass Spectrometry, Glycans, Supramolecular Chemistry, Ion Soft-Landing
Manchester, UK
Joined February 2020
Excited to share that I got selected as an Emerging Analytical Scientist and interviewed for the @ChemEurope journal Analytical Science Advances! Thank you to Sebastian Eeltink and @realBioMassSpec for inviting me, and to @MSHeretic for the nomination! https://t.co/IfL8o5Po4f
chemistry-europe.onlinelibrary.wiley.com
Click on the article title to read more.
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Pleased to share our newest paper in Journal of Chemical Education! Many thanks to all the people involved in this group experiment, particularly supervisor Perdita Barran and co-first authors Matthew Venables and Emily Hicks! https://t.co/qfBUxiNdZQ
pubs.acs.org
A course-based undergraduate research experience (CURE) experiment has been developed, which combines electrospray ionization ion mobility mass spectrometry (ESI-IM-MS) with computational modeling...
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Glad to see this paper out!
@GeueNiklas, @vixklen, @PerditaB & teams at @UoMChemistry, @UoMMIB & @mpifkf used ion mobility MS and STM to characterize polymetallic horseshoe oligomers in the gas phase and surfaces #openaccess 🔓
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#EurJOC New work by @pagelgroup, @GeueNiklas, @KimGreis and team! They studied galactosyl and mannosyl cations with levulinoyl groups, showing how the intermediate structure correlates with glycosylation stereoselectivity #openaccess 🔓
chemistry-europe.onlinelibrary.wiley.com
The influence of levulinoyl protecting groups on the glycosylation stereoselectivity and glycosyl cation structure is studied for galactose and mannose building blocks.
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Glad to share our new paper in @an_chem where we distinguish isomeric caffeine metabolites using cryogenic gas-phase infrared spectroscopy through their different protomers and tautomers! Many thanks to all co-authors involved! https://t.co/pD88ufAzEb
pubs.acs.org
Caffeine is metabolized through various pathways in the human body, with the primary two steps yielding isomeric products. Distinguishing these metabolites is crucial for mass spectrometry-based...
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Happy to share our newest preprint in which we distinguish caffeine metabolites using cryogenic gas-phase infrared spectroscopy through the presence of distinct protomers and tautomers! https://t.co/T0tSKQ1k61
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Pleased to share our newest paper on an unexpected family of heterometallic Cr6M2 rings, led by Abdulelah Alsuhaymi and Richard Winpenny! @InorgChem
https://t.co/WMVT4zEwJS
pubs.acs.org
Three heterometallic rings, [Pr2NH2][(Pr2NH2)Cr6IIIM2IIF8(BTFB)16] (M is Ni, Co, or Zn, BTFBH = 3,5-bis(trifluoromethyl)benzoic acid) are reported, templated about a di-n-propylammonium cation. The...
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Check out the new minireview by @GeueNiklas, Marc Safferthal and @pagelgroup, discussing fragmentation mechanisms of oligosaccharides in collision-induced dissociation mass spectrometry! #AngewandteReview #openaccess 🔓
onlinelibrary.wiley.com
Glycan fragmentation with collision-induced dissociation (CID) mass spectrometry (MS) leads to a range of specific disassembly mechanisms, which are being reviewed in detail.
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Our new minireview is out in @angew_chem, discussing the mechanisms of glycan fragmentation in collision-induced dissociation mass spectrometry! Many thanks to Marc Safferthal and @pagelgroup, and to Eunice Moon for designing the frontispiece below! https://t.co/P1jigml3fi
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Pleased to share our newest paper in @ChemCommun, showing how mass spectrometry and density functional theory can decipher the energetics of carboxylate-metal bonds in polymetallic rings. Many thanks to all authors, including @Trujillo_Group! https://t.co/TiegN2qVC8
pubs.rsc.org
Using collision-induced dissociation mass spectrometry and density functional theory, we assess the energetics of polymetallic [Cr7NiF8(O2CR)16]− anions in vacuo, showing how the carboxylate influe...
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Great to share our new book chapter on advanced mass spectrometry methods for glycan characterisation, published in the Handbook of Experimental Pharmacology! Many thanks to co-first author @caitlin_wd, Eleonora Renzi, Mathew Bejoy and Kevin Pagel! https://t.co/bc5ebtz5s1
link.springer.com
Mass spectrometry-based techniques have emerged as a gamechanger for the analysis of carbohydrates. Here, we summarize state-of-the-art glycan analysis in vacuo, demonstrating how mass spectrometry,...
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Thrilled to hear that the German Research foundation funded my proposal "Elucidating the Fragmentation Pathways of Glycans for Clinical Glycomics"! Looking forward to pursue gas-phase glycoscience as a Walther-Benjamin fellow at FU Berlin, mentored by @pagelgroup .
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I am very happy and honored, and would like to thank everyone who supported me during my PhD - in particular my supervisors Perdita Barran and Richard Winpenny.
Congratulations to @GeueNiklas who received the Wolfgang Paul Study Award from the German Society for Mass Spectrometry for his thesis "Formation, Characterisation and Disassembly of Metallosupramolecular Complexes in vacuo". 🥳🎉 @BarranGroup
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Happy to share our latest paper in @PCCP! We characterise a polymetallic seahorse-structure in non-crystalline phases, and found some intriguing cyclisation reactions going on in the gas phase! Many thanks to everyone involved! https://t.co/x0BPBGi6hA
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Delighted to see our HDX-MS study of TDP-43-RNA complexes published online today in JACS!
pubs.acs.org
Deposits of aggregated TAR DNA-binding protein 43 (TDP-43) in the brain are associated with several neurodegenerative diseases. It is well established that binding of RNA/DNA to TDP-43 can prevent...
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Advertising for a PhD student to join the group, working on a collaborative project with @Immunocore to use structural MS to improve the manufacturability of biopharmaceuticals - please pass on details to all who might be interested!
findaphd.com
PhD Project - CASE Project: Overcoming host cell protein contamination in the preparation of biopharmaceuticals at University of Leeds, listed on FindAPhD.com
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Happy to share our next preprint in which we characterise a {Cr12Ni3} "seahorse" chain in non-crystalline phases. Particularly interesting are some unexpected gas-phase rearrangements! Many thanks to all authors, particularly Master student Emily Hicks! https://t.co/LjenlwEHcr
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Check out this article by our own @vixklen, in collaboration with @GeueNiklas and others, on self-assembly, rearrangement and disassembly of polymetallic {Cr6} horseshoes in vacuo and on surfaces! https://t.co/KDVYpdnbed
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Nanohoops Favour Light-Induced Energy Transfer over Charge Separation in Porphyrin/[10]CPP/Fullerene Rotaxanes (Max von Delius and co-workers) @mvdelius @uni_ulm @GeueNiklas @PerditaB #openaccess
onlinelibrary.wiley.com
The two different nanohoops in elaborate porphyrin/(aza)[10]CPP/fullerene [2]rotaxanes (CPP: cycloparaphenylene) have been shown to act as “supramolecular shields” and completely prevent through-sp...
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Very happy to share our newest preprint on self-assembly, rearrangement and disassembly of polymetallic {Cr6} horseshoes in vacuo and on surfaces, in collaboration wiht @vixklen! Many thanks to all co-authors from @UoMChemistry and @mpifkf! https://t.co/lJ8eQh4Vk9
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📢Exciting PhD Opportunity | Part of the MobiliTraIN network | Funded by UKRI/Horizon Europe 🎓Earn a PhD from @OfficialUoM 📍Working @WatersCorp, UK 🔬 Alongside R&D 🚀 Develop novel tech to study virus particles 🤝 Collaborate with experts 📅 Deadline: 15th Nov 2024
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