Centre for Evolutionary Therapy
@EvolTherapy
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Our mission is to develop & deploy the next generation of cancer therapy through the integration of mathematical models, patient data & evolutionary principles.
Tampa, FL
Joined March 2018
Todays @EvolTherapy seminar is from our own @ReneeBradyPhD discussing results from pilot funding provided by our Center of Excellence on, Using PROs to optimize treatment timing @mathonco @MoffittNews
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Interested in the evolution of drug resistance? Or working with animal models & clinical data to implement new a @EvolTherapy for NSCLC? The #AndersonLab is hiring a postdoc to work in @mathonco on our @NCIsysbio U54: The Delta Ecology of NSCLC. More here: https://t.co/cbNEA4IXVb
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Insightful new @CR_AACR paper led by #AndersonLab rising star @SciKit_G on using DRL to uncover more personalised adaptive therapies. Key takeaway: Every patient should have their own treatment switch threshold! Also the cover that could have been but never was, maybe next time👇
Could we use deep learning to personalize cancer treatment schedules? We explore this in castrate-resistant prostate cancer, in a new paper out in Cancer Research @CR_AACR: https://t.co/XDTZIuYwYy A tweetorial (or should I now say an eXposition?) [1/11]
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Could we use deep learning to personalize cancer treatment schedules? We explore this in castrate-resistant prostate cancer, in a new paper out in Cancer Research @CR_AACR: https://t.co/XDTZIuYwYy A tweetorial (or should I now say an eXposition?) [1/11]
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We are on the cover of @CellSystemsCP! Cool collaborative paper led by the brilliant @StroblMAR with @mehdiDamaghi @PhilipMaini
@RMWenham @mathoncbro @jillagal @markrt_ @GatenbyLab. A special shout out @EvolTherapy for partially funding this project! @mathonco @MoffittNews
Our June issue is online! On the cover: Illustration showing simulations of tumor growth arranged as the two strands of a DNA helix, shattered by the emblematic double strand break induced by PARP inhibitors https://t.co/CUmFA92QIR
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Could adaptive therapy improve PARPi maintenance for ovarian cancer? I’m very happy and proud to share our new paper, now out in Cell Systems: https://t.co/yfo2azHGcZ A tweetorial [1/12]
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Very happy to share our beautiful integrated @CellSystemsCP paper led by the brilliant @StroblMAR doing both the modelling and experiments, To modulate or to skip: De-escalating PARP inhibitor maintenance therapy in ovarian cancer using adaptive therapy https://t.co/827D4I6INo
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Today is the #MoffittScientificSymposium and the #AndersonLab had posters from @jillagal & @masud_math on our @EvolTherapy trial with @genentech on Basal Cell Carcinoma, as well as a poster from new PhD student Agata Xella on plasticity and drug resistance @mathonco @MoffittNews
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Todays @mathonco research in progress is from #AndersonLab veteran and creative guru @jillagal presenting new results from our on going @EvolTherapy trial: Developing a data to decision support pipeline for advanced basal cell carcinoma adaptive therapy.
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Today we kick off our new joint @EvolTherapy and @NCIsysbio Center seminar series: Quantitative delta ecology and evolution or #QDelta for short. Our 1st seminar is from Dr. Masanobu Komatsu: Drug induction of tertiary lymphoid structure in tumors and its therapeutic benefit.
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Today’s @EvolTherapy seminar is from a collaboration between @mathoncbro & @luddyka along with @GatenbyLab & @ClionaOfarrelly discussing, Evolutionary double-bind treatment using radiotherapy and NK cell-based immunotherapy in prostate cancer @mathonco @MoffittNews
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Super excited to share our new paper in @Annals_Oncology on why, Treatment of evolving cancers will require dynamic decision support. An #AndersonLab collab led by the brilliant @StroblMAR & @jillagal with @markrt_ & @mathoncbro. Very proud of this piece! https://t.co/SPJzYuRk5r
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Thanks to an incredible collaborative team of scientists including Bob #Gatenby @dbasanta @AndriyMarusyk Amer Beg @markrt_ @Sciurusniger @JhanelleGray @ReneeBradyPhD @mathoncbro @sandhya212 @cgatenbee & more, @mathonco will be part of the @NCIsysbio program for the next 5 years!
"While many see cancer evolution as a sequence of genetic changes or mutations, our team believes that to truly understand cancer evolution, you must also consider its dynamic ecology." https://t.co/DmYGkrQ7T7
@EvolTherapy
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Registration for the 11th @mathonco workshop: STEERING Cancer Evolution/Extinction is open https://t.co/n9DfqxZFYW! Held onsite @MoffittNews Oct 29-Nov 3 #MoffittIMO. Thanks to @evoltherapy deluxe travel awards are available on a competitive basis. Apply by 9/30 to be considered!
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This week in #MathOnco 269: IMO Workshop and more... Artwork by @ara_anderson, @jillagal, @cgatenbee 😎💯 Sign up for the newsletter here: https://t.co/RASvJNhauC
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Excited to announce that registration for the 11th @mathonco workshop: STEERING Cancer Evolution/Extinction is open! Held onsite @MoffittNews Oct 29-Nov 3 #MoffittIMO more details: https://t.co/n9DfqxZFYW. Deluxe travel awards are available on a competitive basis, apply by 09/30!
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Todays @mathonco research is from #AndersonLab coder and gui-guru Paul Llamas presenting, Automated Modeling Framework for Lesion and Treatment Analysis @EvolTherapy @MoffittNews
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Then it's our very own Bob #Gatenby @mathonco @MoffittNews presenting, Integrating evolutionary mathematical models into clinical trials. Highlighting results from his @EvolTherapy pilot trial on Metastatic castrate resistant prostate cancer #TranslationalSysBio
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Todays @EvolTherapy seminar was a double act led by our very own Joel Brown @Sciurusniger and Ken Tsai @KYTsaiLab presenting an update on a pilot project funded through the CoE: A UV-induced skin cancer mouse model for testing evolutionary therapies. @mathonco @MoffittNews
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Excited to shared our recent piece in @JCO_ASCO on Evolutionary Dynamics and 'Intermittent Therapy'Â for Metastatic Cancers https://t.co/FGAvy3mEKq with @JadChahoud @Sciurusniger and Bob #Gatenby where we discuss the impact of the induction period @MoffittNews @EvolTherapy
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