Edward Pimentel
@EdwardBPimentel
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Chemist, Dad. (he/him) Loves Bikes, Books and Plants 🇺🇸 🇧🇦 🇷🇴 🇳🇱 🇸🇩 🇧🇪
Joined December 2021
Hot off the press! Our @Martell_Group mini-review on DNA-scaffolded catalysis just dropped in @TrendsChemistry. An interesting look at this unique intersection of catalysis, supramolecular chem, and DNA nanotechnology. Read here:
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New preprint from the Soh lab! Nice work by my labmate Haji - new highly specific steroid aptamers identified using our modified sequencer platform. I've used the progesterone aptamer myself and can vouch for it! #chemtwitter @ChemRxiv
biorxiv.org
Aptamer-based biosensors offer several advantages for detecting small molecules, including chemical stability and compatibility with diverse sensing formats. However, developing highly specific DNA...
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At #ACSFall2025, we caught up with Tejas Shah, who is automating chemistry to ensure food security: https://t.co/vkJe3VT8zg
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A new album!!!! “The Light For Days”, out October 10th 💡 Presave here: https://t.co/HK7X3VvWLb
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Using protein native backbone as ligand for organometallic catalysts without attaching ligands to protein is long sought after. Our MPAA ligand provides a perfect avenue to achieve this, showing high mono-selectivity: Nature Catalysis: https://t.co/c6NFzx8rfa
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Super cool to have our VHPO-catalyzed thioketal cleavage highlighted in OPRD! Thanks so much for the highlight! https://t.co/AyrygF08cX
pubs.acs.org
KFB Lab Alert: Our latest work applying enzymatic halide recycling to thioketal cleavage is now available @ChemRxiv! Congratulations to @ManiksharmaASR and Yue Li on this work! https://t.co/RUIRpPXMkB
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Cool grant program by @AmerChemSociety that supports graduate students whose Masters/PhD is being impacted by canceled grants:
acs.org
To support graduate students (M.S. and Ph.D.), within one year of degree completion, whose education and training were disrupted due to recent termination or cancellation of research grants.The grant...
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Check out the latest preprint from the @Martell_Group: we combined DNA-scaffolded catalysis with DNA-encoded libraries to perform >500,000 parallel reactions on attomole scale! 🧬🧪 Shout out to Caleb and @JeffChem and all of our amazing coauthors! https://t.co/ZKknvF57Dd
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Really great article about teaching undergraduate chemistry the sets a higher bar for the "unknown puzzles" we all remember solving (some fondly, other not so much)! This authentic chemistry learning approach made being a TA at UW-Madison really great!
pubs.acs.org
We present example assessments featuring spectroscopic unknown puzzles, where the solution to the puzzle is the outcome of a known chemical reaction. These spectroscopic exercises engage students in...
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We built a DNA-scaffolded and DNA-encoded high-throughput reaction screening platform that runs 500,000+ reactions in <3 days and can generated data to train predictive models! 🧬🧪 Proud to finally share the preprint: 🔗 https://t.co/ZKknvF57Dd
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I'm grateful to have been recognized as one of the Top 100 applicants for the 2025 #CASFutureLeaders. Congrats to all of the amazing chemists who were selected! 🧪🧬 And thanks to @petercarlton for organizing this awesome program!
Join us in congratulating the 2025 #CASFutureLeaders! We look forward to welcoming these exceptional Ph.D. students and postdoctoral scholars to Columbus, Ohio, and Washington, DC, this August. https://t.co/59m5gdePaD
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When an unusual late-night lab observation leads to something more! Swellable cross-linked protein crystals as a support for enzymes and catalysts, now in @ACS_AMI. H/t Jed, @Ethan_Hartman97, and Eli for all of their work on this! @Martell_Group
https://t.co/E72mOfMHpN
pubs.acs.org
Scaffolding catalytic reactions within porous materials is a powerful strategy to enhance the reaction rates of multicatalytic systems. However, it remains challenging to develop materials with high...
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Doing good science is 90% finding a science buddy to constantly talk to about the project.
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The unreasonable effectiveness of plasmid sequencing as a service (Plasmidsaurus) https://t.co/kWOd8oNOnz i cover @plasmidsaurus, the plasmid sequencing company they are one of the most interesting startups ive ever stumbled across and this essay explains why (3.8k words)
owlposting.com
3.8k words, 18 minutes reading time
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Radical Polarity | Journal of the American Chemical Society @nagiblab @OhioState @TotalSyntheses #Radical #Polarity
pubs.acs.org
The polarity of a radical intermediate profoundly impacts its reactivity and selectivity. To quantify this influence and predict its effects, the electrophilicity/nucleophilicity of >500 radicals has...
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Excited to be working in the @HTSohLab!
#TraineeSpotlight: Edward is a postdoc who researches natural/non-natural aptamers to target analytes that can't be targeted with conventional antibodies. Outside of lab, @EdwardBPimentel likes to read, bake, and spend time with his wife and two daughters (photo @lawrencehallsci)
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Check out this neat paper on photocatalyst activation at cell-cell contacts by my former labmate and fellow DNA enthusiast @XuZhou_102! It's great to see this published!
Check out our new paper! DNA-Directed Activation of Photocatalytic Labeling at Cell–Cell Contact Sites. Congrats to @XuZhou_102, who led this work. Xu just started his own lab at Nanjing University–keep a lookout for his group's exciting DNA nanotech work! https://t.co/aj7CX3kCRw
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Take a look at a cool new perspective looking at biosensors for #ParkinsonsDisease by @gmmaddocks
Out today from the @HTSohLab, this critical perspective on biosensors for #ParkinsonsDisease seeks to pinpoint necessary changes for new sensors to translate into impact for PD patients.
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Out today from the @HTSohLab, this critical perspective on biosensors for #ParkinsonsDisease seeks to pinpoint necessary changes for new sensors to translate into impact for PD patients.
pubs.acs.org
Parkinson’s Disease is the second most common neurological disease in the United States, yet there is no cure, no pinpointed cause, and no definitive diagnostic procedure. Parkinson’s is typically...
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